c2pfam

AT2G35190.1 :

Domain Description Evalue Bits GA Start End
NPV_P10 Nucleopolyhedrovirus P10 protein 0.0025 10 29.80 3 59
Syntaxin-6_N Syntaxin 6, N-terminal 0.00037 13 24.90 3 95
Seryl_tRNA_N Seryl-tRNA synthetase N-terminal domain 0.096 4 27.90 4 27
YkyA Putative cell-wall binding lipoprotein 0.0023 9 22.00 5 110
DUF948 Bacterial protein of unknown function (DUF948) 0.00045 12 28.10 5 62
Laminin_II Laminin Domain II 0.00038 12 27.70 5 54
DUF148 Domain of unknown function DUF148 0.00072 11 23.50 6 45
DUF2203 Uncharacterized conserved protein (DUF2203) 0.006 9 20.80 7 72
Prominin Prominin 2.9E-06 17 31.00 7 227
Vps53_N Vps53-like, N-terminal 0.0084 6 24.00 7 71
Exonuc_VII_L Exonuclease VII, large subunit 0.00013 13 21.70 7 162
Syntaxin_2 Syntaxin-like protein 0.00056 12 30.50 8 102
TMPIT TMPIT-like protein 0.0016 9 22.10 8 97
JHD Jumonji helical domain 0.00091 11 23.40 9 70
Zw10 Centromere/kinetochore Zw10 0.26 1 19.30 9 61
DUF1759 Protein of unknown function (DUF1759) 0.021 6 21.10 9 58
MCPsignal Methyl-accepting chemotaxis protein (MCP) signaling domain 0.045 5 30.00 9 67
Occludin_ELL Occludin homology domain 5.7E-05 15 25.30 10 64
PilJ Type IV pili methyl-accepting chemotaxis transducer N-term 0.92 1 26.60 10 54
BDV_P24 Borna disease virus P24 protein 0.0076 8 25.00 10 69
HEF_HK HEF_HK domain 0.095 5 24.10 11 34
Sec20 Sec20 0.008 8 27.00 17 71
DUF5089 Domain of unknown function (DUF5089) 0.31 2 36.10 21 99
Helo_like_N Fungal N-terminal domain of STAND proteins 0.0001 13 27.20 22 77
Tropomyosin_1 Tropomyosin like 0.00036 12 34.20 24 80
MutS_III MutS domain III 0.0015 10 22.50 30 203
Endotoxin_N delta endotoxin, N-terminal domain 0.0016 10 20.80 31 102
Cauli_AT Aphid transmission protein 0.003 9 21.10 31 71
BLOC1_2 Biogenesis of lysosome-related organelles complex-1 subunit 2 0.0077 8 25.00 33 71
Seryl_tRNA_N Seryl-tRNA synthetase N-terminal domain 0.021 7 27.90 34 71
DUF3450 Protein of unknown function (DUF3450) 0.015 6 26.90 35 97
HEF_HK HEF_HK domain 0.17 4 24.10 35 71
HisKA His Kinase A (phosphoacceptor) domain 0.0099 7 22.40 35 72
Pex24p Integral peroxisomal membrane peroxin 0.086 3 37.10 35 75
DUF2203 Uncharacterized conserved protein (DUF2203) 0.0065 9 20.80 35 96
Tropomyosin_1 Tropomyosin like 0.0023 10 34.20 37 115
LUC7 LUC7 N_terminus 0.011 7 33.00 39 93
CCDC-167 Coiled-coil domain-containing protein 167 0.017 7 27.00 43 106
DUF5667 Domain of unknown function (DUF5667) 0.7 2 27.00 43 53
DUF745 Protein of unknown function (DUF745) 0.1 4 22.40 45 95
DUF1759 Protein of unknown function (DUF1759) 0.19 3 21.10 45 107
KLRAQ Predicted coiled-coil domain-containing protein 0.055 5 22.40 45 106
PilJ Type IV pili methyl-accepting chemotaxis transducer N-term 0.013 7 26.60 49 90
Cauli_AT Aphid transmission protein 0.00053 11 21.10 89 192
DUF5667 Domain of unknown function (DUF5667) 0.0067 8 27.00 122 190
Zw10 Centromere/kinetochore Zw10 0.00024 11 19.30 129 198
Helo_like_N Fungal N-terminal domain of STAND proteins 0.07 4 27.20 130 196
Syntaxin_2 Syntaxin-like protein 0.081 5 30.50 135 209
LUC7 LUC7 N_terminus 0.00067 11 33.00 136 191
YkyA Putative cell-wall binding lipoprotein 0.019 6 22.00 136 198
DUF3994 Domain of unknown function (DUF3994) 0.00062 12 25.00 137 209
DUF948 Bacterial protein of unknown function (DUF948) 0.14 4 28.10 137 172
Vps53_N Vps53-like, N-terminal 0.00027 11 24.00 138 210
Seryl_tRNA_N Seryl-tRNA synthetase N-terminal domain 0.061 5 27.90 143 187
DUF148 Domain of unknown function DUF148 0.29 3 23.50 144 190
BDV_P24 Borna disease virus P24 protein 0.2 3 25.00 144 213
MCPsignal Methyl-accepting chemotaxis protein (MCP) signaling domain 0.00016 13 30.00 144 211
DUF745 Protein of unknown function (DUF745) 0.0089 7 22.40 145 206
V-SNARE_C Snare region anchored in the vesicle membrane C-terminus 8.1E-08 24 24.80 151 208
DUF3450 Protein of unknown function (DUF3450) 0.0012 10 26.90 151 210
Sec20 Sec20 1.9E-09 29 27.00 152 232
PilJ Type IV pili methyl-accepting chemotaxis transducer N-term 0.12 4 26.60 154 208
Endotoxin_N delta endotoxin, N-terminal domain 0.13 3 20.80 155 196
DUF1759 Protein of unknown function (DUF1759) 0.0044 8 21.10 155 205
Laminin_II Laminin Domain II 0.0064 8 27.70 155 211
TMPIT TMPIT-like protein 0.024 5 22.10 156 217
DUF2203 Uncharacterized conserved protein (DUF2203) 0.21 4 20.80 158 201
DUF5089 Domain of unknown function (DUF5089) 0.0002 13 36.10 158 208
KLRAQ Predicted coiled-coil domain-containing protein 0.0051 9 22.40 160 210
DUF948 Bacterial protein of unknown function (DUF948) 0.017 7 28.10 161 206
NPV_P10 Nucleopolyhedrovirus P10 protein 0.039 6 29.80 162 196
BLOC1_2 Biogenesis of lysosome-related organelles complex-1 subunit 2 0.015 7 25.00 164 196
Seryl_tRNA_N Seryl-tRNA synthetase N-terminal domain 0.23 3 27.90 172 206
Pex24p Integral peroxisomal membrane peroxin 0.0067 7 37.10 174 237
Occludin_ELL Occludin homology domain 0.83 2 25.30 174 210
HisKA His Kinase A (phosphoacceptor) domain 0.66 2 22.40 175 189
CCDC-167 Coiled-coil domain-containing protein 167 0.91 1 27.00 180 199
DUF948 Bacterial protein of unknown function (DUF948) 0.36 3 28.10 218 245

265

NPV_P10
Syntaxin-6_N
Seryl_tRNA_N
YkyA
DUF948
Laminin_II
DUF148
DUF2203
Prominin
Vps53_N
Exonuc_VII_L
Syntaxin_2
TMPIT
JHD
Zw10
DUF1759
MCPsignal
Occludin_ELL
PilJ
BDV_P24
HEF_HK
Sec20
DUF5089
Helo_like_N
Tropomyosin_1
MutS_III
Endotoxin_N
Cauli_AT
BLOC1_2
Seryl_tRNA_N
DUF3450
HEF_HK
HisKA
Pex24p
DUF2203
Tropomyosin_1
LUC7
CCDC-167
DUF5667
DUF745
DUF1759
KLRAQ
PilJ
Cauli_AT
DUF5667
Zw10
Helo_like_N
Syntaxin_2
LUC7
YkyA
DUF3994
DUF948
Vps53_N
Seryl_tRNA_N
DUF148
BDV_P24
MCPsignal
DUF745
V-SNARE_C
DUF3450
Sec20
PilJ
Endotoxin_N
DUF1759
Laminin_II
TMPIT
DUF2203
DUF5089
KLRAQ
DUF948
NPV_P10
BLOC1_2
Seryl_tRNA_N
Pex24p
Occludin_ELL
HisKA
CCDC-167
DUF948

References:

KLRAQ

DUF745

DUF3450

Prominin
11467842 Rat prominin, like its mouse and human orthologues, is a pentaspan membrane glycoprotein. Biochem Biophys Res Commun 2001;285:939-944.
10587575 A frameshift mutation in prominin (mouse)-like 1 causes human retinal degeneration. Hum Mol Genet 2000;9:27-34.

V-SNARE_C
19064671 Binding interactions control SNARE specificity in vivo. J Cell Biol. 2008;183:1089-1100.

MutS_III
9722634 Domain organization and functional analysis of Thermus thermophilus MutS protein [published erratum appears in Nucleic Acids Res 1998 Oct 15;26(20):following 4789] Nucleic Acids Res 1998;26:4153-4159.
8036718 Colon cancer and DNA repair: have mismatches met their match? Trends Genet 1994;10:164-168.
8510668 The yeast gene MSH3 defines a new class of eukaryotic MutS homologues. Mol Gen Genet 1993;239:97-108.
11048710 Crystal structures of mismatch repair protein MutS and its complex with a substrate DNA. Nature 2000;407:703-710.

DUF2203

DUF5667

PilJ

Seryl_tRNA_N
8654381 The crystal structure of the ternary complex of T.thermophilus seryl-tRNA synthetase with tRNA(Ser) and a seryl-adenylate analogue reveals a conformational switch in the active site. EMBO J 1996;15:2834-2842.

Laminin_II
3182802 Laminin, a multidomain protein. The A chain has a unique globular domain and homology with the basement membrane proteoglycan and the laminin B chains. J Biol Chem 1988;263:16536-16544.

HEF_HK

DUF948

LUC7
11804584 Composition and functional characterization of the yeast spliceosomal penta-snRNP. Mol Cell 2002;9:31-44.
10500099 Luc7p, a novel yeast U1 snRNP protein with a role in 5' splice site recognition. Genes Dev 1999;13:2425-2438.
11170747 Characterization of a widely expressed gene (LUC7-LIKE; LUC7L) defining the centromeric boundary of the human alpha-globin domain. Genomics 2001;71:307-314.
10631324 CROP/Luc7A, a novel serine/arginine-rich nuclear protein, isolated from cisplatin-resistant cell line. FEBS Lett 2000;465:153-156.

TMPIT

BDV_P24

Tropomyosin_1

Syntaxin-6_N
12082176 Three-dimensional structure of the amino-terminal domain of syntaxin 6, a SNAP-25 C homolog. Proc Natl Acad Sci U S A. 2002;99:9184-9189.

HisKA
9989504 Structure of CheA, a signal-transducing histidine kinase. Cell 1999;96:131-141.

DUF148

Cauli_AT
10601029 Aphid transmission of cauliflower mosaic virus requires the viral PIII protein. EMBO J 1999;18:7077-7085.
6311674 Aphid transmission and a polypeptide are specified by a defined region of the cauliflower mosaic virus genome. Gene 1983;23:15-23.

CCDC-167

Helo_like_N

Pex24p
12707309 YHR150w and YDR479c encode peroxisomal integral membrane proteins involved in the regulation of peroxisome number, size, and distribution in Saccharomyces cerevisiae. J Cell Biol 2003;161:321-332.

BLOC1_2
15102850 Identification of snapin and three novel proteins (BLOS1, BLOS2, and BLOS3/reduced pigmentation) as subunits of biogenesis of lysosome-related organelles complex-1 (BLOC-1). J Biol Chem. 2004;279:28393-28401.

MCPsignal
1601874 Sequence and characterization of Bacillus subtilis CheW. J Biol Chem 1992;267:12055-12060.

Exonuc_VII_L
6284744 Subunit structure of Escherichia coli exonuclease VII. J Biol Chem 1982;257:8799-8805.

Occludin_ELL
8276896 Occludin: a novel integral membrane protein localizing at tight junctions. J Cell Biol 1993;123:1777-1788.
8596958 An RNA polymerase II elongation factor encoded by the human ELL gene. Science 1996;271:1873-1876.
16081103 Structure of the conserved cytoplasmic C-terminal domain of occludin: identification of the ZO-1 binding surface. J Mol Biol. 2005;352:151-164.

DUF3994

Zw10
11146659 Rough deal and Zw10 are required for the metaphase checkpoint in Drosophila. Nat Cell Biol 2000;2:939-943.
11146660 Human Zw10 and ROD are mitotic checkpoint proteins that bind to kinetochores. Nat Cell Biol 2000;2:944-947.

Syntaxin_2

YkyA
16684363 Conserved genes in a path from commensalism to pathogenicity: comparative phylogenetic profiles of Staphylococcus epidermidis RP62A and ATCC12228. BMC Genomics. 2006;7:112.

JHD

Sec20
8334998 The TIP1 gene of Saccharomyces cerevisiae encodes an 80 kDa cytoplasmic protein that interacts with the cytoplasmic domain of Sec20p. EMBO J 1993;12:2831-2840.

DUF1759

Vps53_N
1063730 A new translocation in chronic myelogenous leukemia. Hum Genet 1976;32:229-232.

Endotoxin_N
1658659 Crystal structure of insecticidal delta-endotoxin from Bacillus thuringiensis at 2.5 angstroms resolution. Nature 1991;353:815-821.
9729609 Bacillus thuringiensis and its pesticidal crystal proteins. Microbiol Mol Biol Rev 1998;62:775-806.

DUF5089

NPV_P10
9634101 The single-nucleocapsid nucleopolyhedrovirus of Buzura suppressaria encodes a P10 protein. J Gen Virol 1998;79:1553-1562.

Domain	Description	Evalue	Bits	GA	Start	End
NPV_P10	Nucleopolyhedrovirus P10 protein	0.0025	10	29.80	3	59
Syntaxin-6_N	Syntaxin 6, N-terminal	0.00037	13	24.90	3	95
Seryl_tRNA_N	Seryl-tRNA synthetase N-terminal domain	0.096	4	27.90	4	27
YkyA	Putative cell-wall binding lipoprotein	0.0023	9	22.00	5	110
DUF948	Bacterial protein of unknown function (DUF948)	0.00045	12	28.10	5	62
Laminin_II	Laminin Domain II	0.00038	12	27.70	5	54
DUF148	Domain of unknown function DUF148	0.00072	11	23.50	6	45
DUF2203	Uncharacterized conserved protein (DUF2203)	0.006	9	20.80	7	72
Prominin	Prominin	2.9E-06	17	31.00	7	227
Vps53_N	Vps53-like, N-terminal	0.0084	6	24.00	7	71
Exonuc_VII_L	Exonuclease VII, large subunit	0.00013	13	21.70	7	162
Syntaxin_2	Syntaxin-like protein	0.00056	12	30.50	8	102
TMPIT	TMPIT-like protein	0.0016	9	22.10	8	97
JHD	Jumonji helical domain	0.00091	11	23.40	9	70
Zw10	Centromere/kinetochore Zw10	0.26	1	19.30	9	61
DUF1759	Protein of unknown function (DUF1759)	0.021	6	21.10	9	58
MCPsignal	Methyl-accepting chemotaxis protein (MCP) signaling domain	0.045	5	30.00	9	67
Occludin_ELL	Occludin homology domain	5.7E-05	15	25.30	10	64
PilJ	Type IV pili methyl-accepting chemotaxis transducer N-term	0.92	1	26.60	10	54
BDV_P24	Borna disease virus P24 protein	0.0076	8	25.00	10	69
HEF_HK	HEF_HK domain	0.095	5	24.10	11	34
Sec20	Sec20	0.008	8	27.00	17	71
DUF5089	Domain of unknown function (DUF5089)	0.31	2	36.10	21	99
Helo_like_N	Fungal N-terminal domain of STAND proteins	0.0001	13	27.20	22	77
Tropomyosin_1	Tropomyosin like	0.00036	12	34.20	24	80
MutS_III	MutS domain III	0.0015	10	22.50	30	203
Endotoxin_N	delta endotoxin, N-terminal domain	0.0016	10	20.80	31	102
Cauli_AT	Aphid transmission protein	0.003	9	21.10	31	71
BLOC1_2	Biogenesis of lysosome-related organelles complex-1 subunit 2	0.0077	8	25.00	33	71
Seryl_tRNA_N	Seryl-tRNA synthetase N-terminal domain	0.021	7	27.90	34	71
DUF3450	Protein of unknown function (DUF3450)	0.015	6	26.90	35	97
HEF_HK	HEF_HK domain	0.17	4	24.10	35	71
HisKA	His Kinase A (phosphoacceptor) domain	0.0099	7	22.40	35	72
Pex24p	Integral peroxisomal membrane peroxin	0.086	3	37.10	35	75
DUF2203	Uncharacterized conserved protein (DUF2203)	0.0065	9	20.80	35	96
Tropomyosin_1	Tropomyosin like	0.0023	10	34.20	37	115
LUC7	LUC7 N_terminus	0.011	7	33.00	39	93
CCDC-167	Coiled-coil domain-containing protein 167	0.017	7	27.00	43	106
DUF5667	Domain of unknown function (DUF5667)	0.7	2	27.00	43	53
DUF745	Protein of unknown function (DUF745)	0.1	4	22.40	45	95
DUF1759	Protein of unknown function (DUF1759)	0.19	3	21.10	45	107
KLRAQ	Predicted coiled-coil domain-containing protein	0.055	5	22.40	45	106
PilJ	Type IV pili methyl-accepting chemotaxis transducer N-term	0.013	7	26.60	49	90
Cauli_AT	Aphid transmission protein	0.00053	11	21.10	89	192
DUF5667	Domain of unknown function (DUF5667)	0.0067	8	27.00	122	190
Zw10	Centromere/kinetochore Zw10	0.00024	11	19.30	129	198
Helo_like_N	Fungal N-terminal domain of STAND proteins	0.07	4	27.20	130	196
Syntaxin_2	Syntaxin-like protein	0.081	5	30.50	135	209
LUC7	LUC7 N_terminus	0.00067	11	33.00	136	191
YkyA	Putative cell-wall binding lipoprotein	0.019	6	22.00	136	198
DUF3994	Domain of unknown function (DUF3994)	0.00062	12	25.00	137	209
DUF948	Bacterial protein of unknown function (DUF948)	0.14	4	28.10	137	172
Vps53_N	Vps53-like, N-terminal	0.00027	11	24.00	138	210
Seryl_tRNA_N	Seryl-tRNA synthetase N-terminal domain	0.061	5	27.90	143	187
DUF148	Domain of unknown function DUF148	0.29	3	23.50	144	190
BDV_P24	Borna disease virus P24 protein	0.2	3	25.00	144	213
MCPsignal	Methyl-accepting chemotaxis protein (MCP) signaling domain	0.00016	13	30.00	144	211
DUF745	Protein of unknown function (DUF745)	0.0089	7	22.40	145	206
V-SNARE_C	Snare region anchored in the vesicle membrane C-terminus	8.1E-08	24	24.80	151	208
DUF3450	Protein of unknown function (DUF3450)	0.0012	10	26.90	151	210
Sec20	Sec20	1.9E-09	29	27.00	152	232
PilJ	Type IV pili methyl-accepting chemotaxis transducer N-term	0.12	4	26.60	154	208
Endotoxin_N	delta endotoxin, N-terminal domain	0.13	3	20.80	155	196
DUF1759	Protein of unknown function (DUF1759)	0.0044	8	21.10	155	205
Laminin_II	Laminin Domain II	0.0064	8	27.70	155	211
TMPIT	TMPIT-like protein	0.024	5	22.10	156	217
DUF2203	Uncharacterized conserved protein (DUF2203)	0.21	4	20.80	158	201
DUF5089	Domain of unknown function (DUF5089)	0.0002	13	36.10	158	208
KLRAQ	Predicted coiled-coil domain-containing protein	0.0051	9	22.40	160	210
DUF948	Bacterial protein of unknown function (DUF948)	0.017	7	28.10	161	206
NPV_P10	Nucleopolyhedrovirus P10 protein	0.039	6	29.80	162	196
BLOC1_2	Biogenesis of lysosome-related organelles complex-1 subunit 2	0.015	7	25.00	164	196
Seryl_tRNA_N	Seryl-tRNA synthetase N-terminal domain	0.23	3	27.90	172	206
Pex24p	Integral peroxisomal membrane peroxin	0.0067	7	37.10	174	237
Occludin_ELL	Occludin homology domain	0.83	2	25.30	174	210
HisKA	His Kinase A (phosphoacceptor) domain	0.66	2	22.40	175	189
CCDC-167	Coiled-coil domain-containing protein 167	0.91	1	27.00	180	199
DUF948	Bacterial protein of unknown function (DUF948)	0.36	3	28.10	218	245