c2pfam

AT2G47000.1 :

Domain Description Evalue Bits GA Start End
ABC_membrane ABC transporter transmembrane region 0 202 22.00 63 335
AAA_29 P-loop containing region of AAA domain 2.1E-05 16 27.00 402 429
ABC_tran ABC transporter 1.2E-35 114 23.10 404 551
AAA_25 AAA domain 0.0031 8 27.00 404 429
Sigma54_activat Sigma-54 interaction domain 0.012 7 20.20 406 437
AAA_7 P-loop containing dynein motor region 0.0041 8 25.80 406 432
AAA_30 AAA domain 0.00027 12 27.00 408 566
AAA_15 AAA ATPase domain 0.00059 11 32.10 409 468
TsaE Threonylcarbamoyl adenosine biosynthesis protein TsaE 0.088 4 26.60 409 432
AAA_23 AAA domain 0.021 7 27.00 410 431
DEAD DEAD/DEAH box helicase 0.0021 9 20.60 410 568
AAA_16 AAA ATPase domain 3.9E-06 19 32.60 410 567
DLIC Dynein light intermediate chain (DLIC) 0.24 1 19.30 410 441
KAP_NTPase KAP family P-loop domain 0.0043 8 20.00 411 586
APS_kinase Adenylylsulphate kinase 0.0037 9 20.70 412 449
RsgA_GTPase RsgA GTPase 0.00032 12 30.00 412 433
Mg_chelatase Magnesium chelatase, subunit ChlI 0.39 1 20.30 412 433
AAA_22 AAA domain 2.5E-05 16 27.00 413 574
DUF815 Protein of unknown function (DUF815) 0.0012 9 20.10 413 496
AAA_24 AAA domain 0.0068 8 27.00 413 434
NACHT NACHT domain 0.021 6 20.40 414 430
Zeta_toxin Zeta toxin 6.9E-05 14 20.10 414 453
G-alpha G-protein alpha subunit 0.00018 12 20.10 414 439
NB-ARC NB-ARC domain 0.025 5 23.50 414 432
NTPase_1 NTPase 0.04 5 23.90 415 452
DUF87 Domain of unknown function DUF87 0.00044 12 20.90 415 446
AAA_18 AAA domain 0.016 7 29.40 415 434
PRK Phosphoribulokinase / Uridine kinase family 0.013 7 20.60 415 436
Roc Ras of Complex, Roc, domain of DAPkinase 0.08 5 27.00 415 436
AAA_33 AAA domain 0.019 7 27.00 415 430
AAA_5 AAA domain (dynein-related subfamily) 0.0052 8 20.80 415 436
MMR_HSR1 GTPase of unknown function 0.021 6 24.50 415 431
Ploopntkinase3 P-loop Nucleotide Kinase3 0.008 7 27.00 415 437
AAA_21 AAA domain, putative AbiEii toxin, Type IV TA system 0.0038 8 27.00 416 448
RNA_helicase RNA helicase 0.11 4 21.50 416 431
AAA_17 AAA domain 0.015 7 27.00 418 452
SMC_N RecF/RecN/SMC N terminal domain 8E-06 17 40.00 467 595
ABC_ATPase Predicted ATPase of the ABC class 1.6E-05 15 19.30 498 552
SbcCD_C Putative exonuclease SbcCD, C subunit 0.00093 11 27.00 539 566
ABC_membrane ABC transporter transmembrane region 0 213 22.00 720 993
DUF2585 Protein of unknown function (DUF2585) 0.00087 10 25.00 783 874
AAA_29 P-loop containing region of AAA domain 8.5E-06 17 27.00 1060 1087
ABC_tran ABC transporter 4.8E-37 119 23.10 1061 1210
TsaE Threonylcarbamoyl adenosine biosynthesis protein TsaE 0.028 6 26.60 1062 1090
AAA_16 AAA ATPase domain 2.4E-05 16 32.60 1066 1097
DEAD DEAD/DEAH box helicase 0.0002 13 20.60 1066 1227
AAA_7 P-loop containing dynein motor region 0.0019 9 25.80 1066 1094
Sigma54_activat Sigma-54 interaction domain 0.038 5 20.20 1067 1092
AAA_25 AAA domain 0.0078 7 27.00 1067 1088
AAA_15 AAA ATPase domain 0.00059 11 32.10 1067 1097
RsgA_GTPase RsgA GTPase 7.6E-05 14 30.00 1067 1093
DLIC Dynein light intermediate chain (DLIC) 0.0015 9 19.30 1068 1099
KAP_NTPase KAP family P-loop domain 0.018 6 20.00 1069 1233
Mg_chelatase Magnesium chelatase, subunit ChlI 0.0071 7 20.30 1069 1128
AAA_24 AAA domain 0.0017 9 27.00 1070 1108
APS_kinase Adenylylsulphate kinase 0.0043 8 20.70 1070 1109
DUF815 Protein of unknown function (DUF815) 0.0013 9 20.10 1070 1127
AAA_30 AAA domain 0.0016 10 27.00 1071 1101
Zeta_toxin Zeta toxin 0.00091 10 20.10 1071 1110
DUF87 Domain of unknown function DUF87 0.0037 9 20.90 1071 1092
G-alpha G-protein alpha subunit 0.00075 10 20.10 1072 1097
SMC_N RecF/RecN/SMC N terminal domain 0.053 4 40.00 1072 1088
AAA_22 AAA domain 1.5E-05 17 27.00 1072 1223
NACHT NACHT domain 0.013 7 20.40 1072 1088
NB-ARC NB-ARC domain 0.068 4 23.50 1072 1088
AAA_23 AAA domain 0.013 7 27.00 1072 1090
NTPase_1 NTPase 0.13 4 23.90 1073 1091
AAA_18 AAA domain 0.021 7 29.40 1073 1092
PRK Phosphoribulokinase / Uridine kinase family 0.023 6 20.60 1073 1093
Roc Ras of Complex, Roc, domain of DAPkinase 0.04 6 27.00 1073 1091
AAA_33 AAA domain 0.037 6 27.00 1073 1088
AAA_5 AAA domain (dynein-related subfamily) 0.005 8 20.80 1073 1096
MMR_HSR1 GTPase of unknown function 0.01 7 24.50 1073 1090
Ploopntkinase3 P-loop Nucleotide Kinase3 0.0032 9 27.00 1073 1097
AAA_21 AAA domain, putative AbiEii toxin, Type IV TA system 0.0014 10 27.00 1074 1103
RNA_helicase RNA helicase 0.068 5 21.50 1074 1091
AAA_17 AAA domain 0.24 3 27.00 1076 1094
SMC_N RecF/RecN/SMC N terminal domain 3.9E-07 21 40.00 1125 1253
ABC_ATPase Predicted ATPase of the ABC class 0.0034 8 19.30 1160 1212
SbcCD_C Putative exonuclease SbcCD, C subunit 0.0074 8 27.00 1198 1224

1286

ABC_membrane
AAA_29
ABC_tran
AAA_25
Sigma54_activat
AAA_7
AAA_30
AAA_15
TsaE
AAA_23
DEAD
AAA_16
DLIC
KAP_NTPase
APS_kinase
RsgA_GTPase
Mg_chelatase
AAA_22
DUF815
AAA_24
NACHT
Zeta_toxin
G-alpha
NB-ARC
NTPase_1
DUF87
AAA_18
PRK
Roc
AAA_33
AAA_5
MMR_HSR1
Ploopntkinase3
AAA_21
RNA_helicase
AAA_17
SMC_N
ABC_ATPase
SbcCD_C
ABC_membrane
DUF2585
AAA_29
ABC_tran
TsaE
AAA_16
DEAD
AAA_7
Sigma54_activat
AAA_25
AAA_15
RsgA_GTPase
DLIC
KAP_NTPase
Mg_chelatase
AAA_24
APS_kinase
DUF815
AAA_30
Zeta_toxin
DUF87
G-alpha
SMC_N
AAA_22
NACHT
NB-ARC
AAA_23
NTPase_1
AAA_18
PRK
Roc
AAA_33
AAA_5
MMR_HSR1
Ploopntkinase3
AAA_21
RNA_helicase
AAA_17
SMC_N
ABC_ATPase
SbcCD_C

References:

MMR_HSR1
8180467 Structure and evolution of a member of a new subfamily of GTP-binding proteins mapping to the human MHC class I region. Mamm Genome 1994;5:100-105.

RsgA_GTPase

SbcCD_C

Zeta_toxin
12571357 Crystal structure of the plasmid maintenance system epsilon/zeta: functional mechanism of toxin zeta and inactivation by epsilon 2 zeta 2 complex formation. Proc Natl Acad Sci U S A 2003;100:1661-1666.

DUF2585

TsaE

DEAD
10322435 Unwinding RNA in Saccharomyces cerevisiae: DEAD-box proteins and related families. Trends Biochem Sci 1999;24:192-198.
9862990 The DEAD box RNA helicase family in Arabidopsis thaliana. Nucleic Acids Res 1999;27:628-636.

PRK
9548738 The crystal structure of phosphoribulokinase from Rhodobacter sphaeroides reveals a fold similar to that of adenylate kinase. Biochemistry 1998;37:5074-5085.
17143579 Functional characterization of a gene encoding a dual domain for uridine kinase and uracil phosphoribosyltransferase in Arabidopsis thaliana. Plant Mol Biol. 2007;63:465-477.

RNA_helicase
2546125 Two related superfamilies of putative helicases involved in replication, recombination, repair and expression of DNA and RNA genomes. Nucleic Acids Res 1989;17:4713-4730.

G-alpha
8073283 Structures of active conformations of Gi alpha 1 and the mechanism of GTP hydrolysis. Science 1994;265:1405-1412.
8851656 How G proteins work: a continuing story. Trends Biochem Sci 1996;21:41-44.

NTPase_1

DUF815

KAP_NTPase
15128444 A novel family of P-loop NTPases with an unusual phyletic distribution and transmembrane segments inserted within the NTPase domain. Genome Biol 2004;5:R30.

AAA_7

Roc

NACHT
10782090 The NACHT family - a new group of predicted NTPases implicated in apoptosis and MHC transcription activation. Trends Biochem Sci 2000;25:223-224.

AAA_33

Ploopntkinase3

AAA_30

AAA_29

Sigma54_activat
11544185 Binding of transcriptional activators to sigma 54 in the presence of the transition state analog ADP-aluminum fluoride: insights into activator mechanochemical action. Genes Dev 2001;15:2282-2294.
12618438 Domain Architectures of sigma(54)-Dependent Transcriptional Activators. J Bacteriol 2003;185:1757-1767.

AAA_5
7646486 A 200-amino acid ATPase module in search of a basic function. Bioessays 1995;17:639-650.
9927482 AAA+: A class of chaperone-like ATPases associated with the assembly, operation, and disassembly of protein complexes. Genome Res 1999;9:27-43.

AAA_25

AAA_24

AAA_23

AAA_22

AAA_21

AAA_18

AAA_17

AAA_16

AAA_15

APS_kinase
9786849 Adenosine 5'-phosphosulfate kinase from Penicillium chrysogenum. site- directed mutagenesis at putative phosphoryl-accepting and ATP P-loop residues. J Biol Chem 1998;273:28583-28589.

ABC_tran
1864505 Homology between proteins controlling Streptomyces fradiae tylosin resistance and ATP-binding transport. Gene 1991;102:27-32.
1977073 Structure and function of haemolysin B,P-glycoprotein and other members of a novel family of membrane translocators. Mol Microbiol 1990;4:873-880.
2229036 Binding protein-dependent transport systems. J Bioenerg Biomembr 1990;22:571-592.
9872322 Crystal structure of the ATP-binding subunit of an ABC transporter. Nature 1998;396:703-707.

Mg_chelatase
9359397 Mechanism and regulation of Mg-chelatase. Biochem J 1997;327:321-333.
9457877 Reconstitution of an active magnesium chelatase enzyme complex from the bchI, -D, and -H gene products of the green sulfur bacterium Chlorobium vibrioforme expressed in Escherichia coli. J Bacteriol 1998;180:699-704.

ABC_membrane

ABC_ATPase

NB-ARC
9545207 The NB-ARC domain: a novel signalling motif shared by plant resistance gene products and regulators of cell death in animals. Curr Biol 1998;8:226-227.

SMC_N
10429180 Structural maintenance of chromosomes (SMC) proteins: conserved molecular properties for multiple biological functions. Eur J Biochem 1999;263:6-13.
9640531 SMC protein complexes and higher-order chromosome dynamics. Curr Opin Cell Biol 1998;10:317-322.

DUF87

DLIC
10545494 Direct interaction of pericentrin with cytoplasmic dynein light intermediate chain contributes to mitotic spindle organization. J Cell Biol 1999;147:481-492.
10893222 Light intermediate chain 1 defines a functional subfraction of cytoplasmic dynein which binds to pericentrin. J Biol Chem 2000;275:32763-32768.
11907264 Identification of a novel light intermediate chain (D2LIC) for mammalian cytoplasmic dynein 2. Mol Biol Cell 2002;13:817-829.

Domain	Description	Evalue	Bits	GA	Start	End
ABC_membrane	ABC transporter transmembrane region	0	202	22.00	63	335
AAA_29	P-loop containing region of AAA domain	2.1E-05	16	27.00	402	429
ABC_tran	ABC transporter	1.2E-35	114	23.10	404	551
AAA_25	AAA domain	0.0031	8	27.00	404	429
Sigma54_activat	Sigma-54 interaction domain	0.012	7	20.20	406	437
AAA_7	P-loop containing dynein motor region	0.0041	8	25.80	406	432
AAA_30	AAA domain	0.00027	12	27.00	408	566
AAA_15	AAA ATPase domain	0.00059	11	32.10	409	468
TsaE	Threonylcarbamoyl adenosine biosynthesis protein TsaE	0.088	4	26.60	409	432
AAA_23	AAA domain	0.021	7	27.00	410	431
DEAD	DEAD/DEAH box helicase	0.0021	9	20.60	410	568
AAA_16	AAA ATPase domain	3.9E-06	19	32.60	410	567
DLIC	Dynein light intermediate chain (DLIC)	0.24	1	19.30	410	441
KAP_NTPase	KAP family P-loop domain	0.0043	8	20.00	411	586
APS_kinase	Adenylylsulphate kinase	0.0037	9	20.70	412	449
RsgA_GTPase	RsgA GTPase	0.00032	12	30.00	412	433
Mg_chelatase	Magnesium chelatase, subunit ChlI	0.39	1	20.30	412	433
AAA_22	AAA domain	2.5E-05	16	27.00	413	574
DUF815	Protein of unknown function (DUF815)	0.0012	9	20.10	413	496
AAA_24	AAA domain	0.0068	8	27.00	413	434
NACHT	NACHT domain	0.021	6	20.40	414	430
Zeta_toxin	Zeta toxin	6.9E-05	14	20.10	414	453
G-alpha	G-protein alpha subunit	0.00018	12	20.10	414	439
NB-ARC	NB-ARC domain	0.025	5	23.50	414	432
NTPase_1	NTPase	0.04	5	23.90	415	452
DUF87	Domain of unknown function DUF87	0.00044	12	20.90	415	446
AAA_18	AAA domain	0.016	7	29.40	415	434
PRK	Phosphoribulokinase / Uridine kinase family	0.013	7	20.60	415	436
Roc	Ras of Complex, Roc, domain of DAPkinase	0.08	5	27.00	415	436
AAA_33	AAA domain	0.019	7	27.00	415	430
AAA_5	AAA domain (dynein-related subfamily)	0.0052	8	20.80	415	436
MMR_HSR1	GTPase of unknown function	0.021	6	24.50	415	431
Ploopntkinase3	P-loop Nucleotide Kinase3	0.008	7	27.00	415	437
AAA_21	AAA domain, putative AbiEii toxin, Type IV TA system	0.0038	8	27.00	416	448
RNA_helicase	RNA helicase	0.11	4	21.50	416	431
AAA_17	AAA domain	0.015	7	27.00	418	452
SMC_N	RecF/RecN/SMC N terminal domain	8E-06	17	40.00	467	595
ABC_ATPase	Predicted ATPase of the ABC class	1.6E-05	15	19.30	498	552
SbcCD_C	Putative exonuclease SbcCD, C subunit	0.00093	11	27.00	539	566
ABC_membrane	ABC transporter transmembrane region	0	213	22.00	720	993
DUF2585	Protein of unknown function (DUF2585)	0.00087	10	25.00	783	874
AAA_29	P-loop containing region of AAA domain	8.5E-06	17	27.00	1060	1087
ABC_tran	ABC transporter	4.8E-37	119	23.10	1061	1210
TsaE	Threonylcarbamoyl adenosine biosynthesis protein TsaE	0.028	6	26.60	1062	1090
AAA_16	AAA ATPase domain	2.4E-05	16	32.60	1066	1097
DEAD	DEAD/DEAH box helicase	0.0002	13	20.60	1066	1227
AAA_7	P-loop containing dynein motor region	0.0019	9	25.80	1066	1094
Sigma54_activat	Sigma-54 interaction domain	0.038	5	20.20	1067	1092
AAA_25	AAA domain	0.0078	7	27.00	1067	1088
AAA_15	AAA ATPase domain	0.00059	11	32.10	1067	1097
RsgA_GTPase	RsgA GTPase	7.6E-05	14	30.00	1067	1093
DLIC	Dynein light intermediate chain (DLIC)	0.0015	9	19.30	1068	1099
KAP_NTPase	KAP family P-loop domain	0.018	6	20.00	1069	1233
Mg_chelatase	Magnesium chelatase, subunit ChlI	0.0071	7	20.30	1069	1128
AAA_24	AAA domain	0.0017	9	27.00	1070	1108
APS_kinase	Adenylylsulphate kinase	0.0043	8	20.70	1070	1109
DUF815	Protein of unknown function (DUF815)	0.0013	9	20.10	1070	1127
AAA_30	AAA domain	0.0016	10	27.00	1071	1101
Zeta_toxin	Zeta toxin	0.00091	10	20.10	1071	1110
DUF87	Domain of unknown function DUF87	0.0037	9	20.90	1071	1092
G-alpha	G-protein alpha subunit	0.00075	10	20.10	1072	1097
SMC_N	RecF/RecN/SMC N terminal domain	0.053	4	40.00	1072	1088
AAA_22	AAA domain	1.5E-05	17	27.00	1072	1223
NACHT	NACHT domain	0.013	7	20.40	1072	1088
NB-ARC	NB-ARC domain	0.068	4	23.50	1072	1088
AAA_23	AAA domain	0.013	7	27.00	1072	1090
NTPase_1	NTPase	0.13	4	23.90	1073	1091
AAA_18	AAA domain	0.021	7	29.40	1073	1092
PRK	Phosphoribulokinase / Uridine kinase family	0.023	6	20.60	1073	1093
Roc	Ras of Complex, Roc, domain of DAPkinase	0.04	6	27.00	1073	1091
AAA_33	AAA domain	0.037	6	27.00	1073	1088
AAA_5	AAA domain (dynein-related subfamily)	0.005	8	20.80	1073	1096
MMR_HSR1	GTPase of unknown function	0.01	7	24.50	1073	1090
Ploopntkinase3	P-loop Nucleotide Kinase3	0.0032	9	27.00	1073	1097
AAA_21	AAA domain, putative AbiEii toxin, Type IV TA system	0.0014	10	27.00	1074	1103
RNA_helicase	RNA helicase	0.068	5	21.50	1074	1091
AAA_17	AAA domain	0.24	3	27.00	1076	1094
SMC_N	RecF/RecN/SMC N terminal domain	3.9E-07	21	40.00	1125	1253
ABC_ATPase	Predicted ATPase of the ABC class	0.0034	8	19.30	1160	1212
SbcCD_C	Putative exonuclease SbcCD, C subunit	0.0074	8	27.00	1198	1224