c2pfam

AT3G04220.1 :

Domain Description Evalue Bits GA Start End
TIR TIR domain 0 184 21.20 62 239
TIR_2 TIR domain 1.7E-17 55 28.00 65 165
NB-ARC NB-ARC domain 1.5E-25 80 23.50 242 481
TniB Bacterial TniB protein 0.00011 12 20.10 244 286
AAA_16 AAA ATPase domain 2.4E-07 22 32.60 248 335
AAA_7 P-loop containing dynein motor region 0.00049 10 25.80 249 292
ABC_tran ABC transporter 8.9E-06 17 23.10 257 353
ATPase_2 ATPase domain predominantly from Archaea 1.1E-06 19 33.20 257 357
Guanylate_kin Guanylate kinase 0.00025 11 20.60 258 290
Rad17 Rad17 cell cycle checkpoint protein 3.4E-05 14 19.70 258 358
AAA_14 AAA domain 4.3E-05 14 27.00 259 361
AAA_24 AAA domain 1.2E-05 16 27.00 260 292
AAA_18 AAA domain 1.7E-07 23 29.40 261 361
AAA_28 AAA domain 0.00023 12 27.00 261 321
AAA ATPase family associated with various cellular activities (AAA) 8.6E-07 20 20.80 263 286
AAA_22 AAA domain 2.2E-06 19 27.00 263 353
RNA_helicase RNA helicase 8.8E-06 17 21.50 263 334
AAA_33 AAA domain 0.00013 13 27.00 264 297
LRR_5 BspA type Leucine rich repeat region (6 copies) 0.16 3 27.70 597 614
LRR_8 Leucine rich repeat 0.068 4 27.00 597 613
LRR_3 Leucine Rich Repeat 2E-05 15 20.20 655 665
LRR_8 Leucine rich repeat 0.0058 7 27.00 668 722
LRR_4 Leucine Rich repeats (2 copies) 0.0022 9 27.00 669 703
LRR_8 Leucine rich repeat 6.3E-06 17 27.00 692 748
LRR_1 Leucine Rich Repeat 0.014 7 20.60 692 711
LRR_4 Leucine Rich repeats (2 copies) 0.0001 13 27.00 715 751
LRR_5 BspA type Leucine rich repeat region (6 copies) 0.0033 8 27.70 715 777
LRR_1 Leucine Rich Repeat 0.032 6 20.60 716 738
LRR_1 Leucine Rich Repeat 0.0018 10 20.60 740 762
LRR_8 Leucine rich repeat 0.0013 9 27.00 756 796
LRR_4 Leucine Rich repeats (2 copies) 0.045 5 27.00 775 794
LRR_1 Leucine Rich Repeat 0.13 4 20.60 788 810
LRR_8 Leucine rich repeat 3.7E-07 21 27.00 804 845
LRR_5 BspA type Leucine rich repeat region (6 copies) 0.0026 8 27.70 805 864
LRR_4 Leucine Rich repeats (2 copies) 7.5E-05 14 27.00 811 845
LRR_1 Leucine Rich Repeat 0.0097 8 20.60 812 834
LRR_1 Leucine Rich Repeat 0.0046 9 20.60 836 855

867

TIR
TIR_2
NB-ARC
TniB
AAA_16
AAA_7
ABC_tran
ATPase_2
Guanylate_kin
Rad17
AAA_14
AAA_24
AAA_18
AAA_28
AAA
AAA_22
RNA_helicase
AAA_33
LRR_5
LRR_8
LRR_3
LRR_8
LRR_4
LRR_8
LRR_1
LRR_4
LRR_5
LRR_1
LRR_1
LRR_8
LRR_4
LRR_1
LRR_8
LRR_5
LRR_4
LRR_1
LRR_1

References:

AAA_16

AAA_14

ABC_tran
1864505 Homology between proteins controlling Streptomyces fradiae tylosin resistance and ATP-binding transport. Gene 1991;102:27-32.
1977073 Structure and function of haemolysin B,P-glycoprotein and other members of a novel family of membrane translocators. Mol Microbiol 1990;4:873-880.
2229036 Binding protein-dependent transport systems. J Bioenerg Biomembr 1990;22:571-592.
9872322 Crystal structure of the ATP-binding subunit of an ABC transporter. Nature 1998;396:703-707.

AAA
7646486 A 200-amino acid ATPase module in search of a basic function. Bioessays 1995;17:639-650.
9927482 AAA+: A class of chaperone-like ATPases associated with the assembly, operation, and disassembly of protein complexes. Genome Res 1999;9:27-43.

LRR_5

LRR_1
7817399 The leucine-rich repeat: a versatile binding motif. Trends Biochem Sci 1994;19:415-421.
8264799 Crystal structure of porcine ribonuclease inhibitor, a protein with leucine-rich repeats. Nature 1993;366:751-756.

AAA_28

LRR_3
7817399 The leucine-rich repeat: a versatile binding motif. Trends Biochem Sci 1994;19:415-421.
8264799 Crystal structure of porcine ribonuclease inhibitor, a protein with leucine-rich repeats. Nature 1993;366:751-756.

TniB
8195081 Transposon Tn5090 of plasmid R751, which carries an integron, is related to Tn7, Mu, and the retroelements. J Bacteriol 1994;176:3257-3268.
8594337 Four genes, two ends, and a res region are involved in transposition of Tn5053: a paradigm for a novel family of transposons carrying either a mer operon or an integron. Mol Microbiol 1995;17:1189-1200.

NB-ARC
9545207 The NB-ARC domain: a novel signalling motif shared by plant resistance gene products and regulators of cell death in animals. Curr Biol 1998;8:226-227.

LRR_8

AAA_7

LRR_4

ATPase_2

AAA_33

TIR_2

Rad17
10208430 hRAD17, a structural homolog of the Schizosaccharomyces pombe RAD17 cell cycle checkpoint gene, stimulates p53 accumulation. Oncogene 1999;18:1689-1699.

Guanylate_kin
1314905 Refined structure of the complex between guanylate kinase and its substrate GMP at 2.0 A resolution. J Mol Biol 1992;224:1127-1141.

RNA_helicase
2546125 Two related superfamilies of putative helicases involved in replication, recombination, repair and expression of DNA and RNA genomes. Nucleic Acids Res 1989;17:4713-4730.

AAA_24

TIR
9013863 The cloning and characterization of human MyD88: a member of an IL-1 receptor related family. FEBS Lett 1997;402:81-84.
9237759 A human homologue of the Drosophila Toll protein signals activation of adaptive immunity [see comments] Nature 1997;388:394-397.
12186654 Toll-like receptors: a family of pattern-recognition receptors in mammals. Genome Biol 2002;3:REVIEWS3011.

AAA_22

AAA_18

Domain	Description	Evalue	Bits	GA	Start	End
TIR	TIR domain	0	184	21.20	62	239
TIR_2	TIR domain	1.7E-17	55	28.00	65	165
NB-ARC	NB-ARC domain	1.5E-25	80	23.50	242	481
TniB	Bacterial TniB protein	0.00011	12	20.10	244	286
AAA_16	AAA ATPase domain	2.4E-07	22	32.60	248	335
AAA_7	P-loop containing dynein motor region	0.00049	10	25.80	249	292
ABC_tran	ABC transporter	8.9E-06	17	23.10	257	353
ATPase_2	ATPase domain predominantly from Archaea	1.1E-06	19	33.20	257	357
Guanylate_kin	Guanylate kinase	0.00025	11	20.60	258	290
Rad17	Rad17 cell cycle checkpoint protein	3.4E-05	14	19.70	258	358
AAA_14	AAA domain	4.3E-05	14	27.00	259	361
AAA_24	AAA domain	1.2E-05	16	27.00	260	292
AAA_18	AAA domain	1.7E-07	23	29.40	261	361
AAA_28	AAA domain	0.00023	12	27.00	261	321
AAA	ATPase family associated with various cellular activities (AAA)	8.6E-07	20	20.80	263	286
AAA_22	AAA domain	2.2E-06	19	27.00	263	353
RNA_helicase	RNA helicase	8.8E-06	17	21.50	263	334
AAA_33	AAA domain	0.00013	13	27.00	264	297
LRR_5	BspA type Leucine rich repeat region (6 copies)	0.16	3	27.70	597	614
LRR_8	Leucine rich repeat	0.068	4	27.00	597	613
LRR_3	Leucine Rich Repeat	2E-05	15	20.20	655	665
LRR_8	Leucine rich repeat	0.0058	7	27.00	668	722
LRR_4	Leucine Rich repeats (2 copies)	0.0022	9	27.00	669	703
LRR_8	Leucine rich repeat	6.3E-06	17	27.00	692	748
LRR_1	Leucine Rich Repeat	0.014	7	20.60	692	711
LRR_4	Leucine Rich repeats (2 copies)	0.0001	13	27.00	715	751
LRR_5	BspA type Leucine rich repeat region (6 copies)	0.0033	8	27.70	715	777
LRR_1	Leucine Rich Repeat	0.032	6	20.60	716	738
LRR_1	Leucine Rich Repeat	0.0018	10	20.60	740	762
LRR_8	Leucine rich repeat	0.0013	9	27.00	756	796
LRR_4	Leucine Rich repeats (2 copies)	0.045	5	27.00	775	794
LRR_1	Leucine Rich Repeat	0.13	4	20.60	788	810
LRR_8	Leucine rich repeat	3.7E-07	21	27.00	804	845
LRR_5	BspA type Leucine rich repeat region (6 copies)	0.0026	8	27.70	805	864
LRR_4	Leucine Rich repeats (2 copies)	7.5E-05	14	27.00	811	845
LRR_1	Leucine Rich Repeat	0.0097	8	20.60	812	834
LRR_1	Leucine Rich Repeat	0.0046	9	20.60	836	855