c2pfam

AT3G06060.1 :

Domain Description Evalue Bits GA Start End
adh_short short chain dehydrogenase 0 155 20.50 41 231
RmlD_sub_bind RmlD substrate binding domain 1.1E-05 14 19.80 43 141
KR KR domain 1E-14 44 22.60 43 205
Epimerase NAD dependent epimerase/dehydratase family 1.2E-09 28 20.60 43 156
GDP_Man_Dehyd GDP-mannose 4,6 dehydratase 8.6E-09 25 27.00 43 157
DFP DNA / pantothenate metabolism flavoprotein 2.9E-05 14 25.60 43 86
NAD_binding_10 NAD(P)H-binding 5.2E-06 16 27.20 46 118
ApbA Ketopantoate reductase PanE/ApbA 8.5E-05 12 21.70 47 119
adh_short_C2 Enoyl-(Acyl carrier protein) reductase 2.1E-31 99 27.00 48 253
Sacchrp_dh_NADP Saccharopine dehydrogenase NADP binding domain 5.3E-05 13 25.10 49 118
Glyco_tran_WecB Glycosyl transferase WecB/TagA/CpsF family 2.7E-05 14 24.80 53 130
NAD_binding_10 NAD(P)H-binding 0.61 -1 27.20 236 262

326

adh_short
RmlD_sub_bind
KR
Epimerase
GDP_Man_Dehyd
DFP
NAD_binding_10
ApbA
adh_short_C2
Sacchrp_dh_NADP
Glyco_tran_WecB
NAD_binding_10

References:

KR

adh_short_C2

adh_short
9735295 The refined crystal structure of Drosophila lebanonensis alcohol dehydrogenase at 1.9 A resolution. J Mol Biol 1998;282:383-399.
10387002 Structure of tropinone reductase-II complexed with NADP+ and pseudotropine at 1.9 A resolution: implication for stereospecific substrate binding and catalysis. Biochemistry 1999;38:7630-7637.

GDP_Man_Dehyd

Glyco_tran_WecB

DFP
3123465 beta-Alanine auxotrophy associated with dfp, a locus affecting DNA synthesis in Escherichia coli. J Bacteriol 1988;170:872-876.

Epimerase
9174344 Structural analysis of UDP-sugar binding to UDP-galactose 4-epimerase from Escherichia coli. Biochemistry 1997;36:6294-6304.

ApbA
9488683 ApbA, the ketopantoate reductase enzyme of Salmonella typhimurium is required for the synthesis of thiamine via the alternative pyrimidine biosynthetic pathway. J Biol Chem 1998;273:5572-5576.
9721324 The panE gene, encoding ketopantoate reductase, maps at 10 minutes and is allelic to apbA in Salmonella typhimurium. J Bacteriol 1998;180:4757-4759.

Sacchrp_dh_NADP

NAD_binding_10

RmlD_sub_bind
12057193 Variation on a Theme of SDR. dTDP-6-Deoxy-L- lyxo-4-Hexulose Reductase (RmlD) Shows a New Mg(2+)-Dependent Dimerization Mode. Structure (Camb) 2002;10:773-786.
10802738 RmlC, the third enzyme of dTDP-L-rhamnose pathway, is a new class of epimerase. Nat Struct Biol 2000;7:398-402.

Domain	Description	Evalue	Bits	GA	Start	End
adh_short	short chain dehydrogenase	0	155	20.50	41	231
RmlD_sub_bind	RmlD substrate binding domain	1.1E-05	14	19.80	43	141
KR	KR domain	1E-14	44	22.60	43	205
Epimerase	NAD dependent epimerase/dehydratase family	1.2E-09	28	20.60	43	156
GDP_Man_Dehyd	GDP-mannose 4,6 dehydratase	8.6E-09	25	27.00	43	157
DFP	DNA / pantothenate metabolism flavoprotein	2.9E-05	14	25.60	43	86
NAD_binding_10	NAD(P)H-binding	5.2E-06	16	27.20	46	118
ApbA	Ketopantoate reductase PanE/ApbA	8.5E-05	12	21.70	47	119
adh_short_C2	Enoyl-(Acyl carrier protein) reductase	2.1E-31	99	27.00	48	253
Sacchrp_dh_NADP	Saccharopine dehydrogenase NADP binding domain	5.3E-05	13	25.10	49	118
Glyco_tran_WecB	Glycosyl transferase WecB/TagA/CpsF family	2.7E-05	14	24.80	53	130
NAD_binding_10	NAD(P)H-binding	0.61	-1	27.20	236	262