c2pfam

AT3G09350.1 :

Domain Description Evalue Bits GA Start End
V-ATPase_H_N V-ATPase subunit H 8.3E-05 12 20.10 6 197
Fes1 Nucleotide exchange factor Fes1 7.8E-12 36 21.40 10 95
V-ATPase_H_C V-ATPase subunit H 0.0009 10 20.80 10 129
Metal_resist Heavy-metal resistance 0.00018 12 29.10 22 91
Enkurin Calmodulin-binding 0.0019 9 23.60 24 63
DUF438 Family of unknown function (DUF438) 0.0011 9 25.00 61 80
SIL1 Nucleotide exchange factor SIL1 1.1E-08 25 35.50 72 217
RICTOR_N Rapamycin-insensitive companion of mTOR, N-term 2.7E-05 13 28.50 96 212
Arm Armadillo/beta-catenin-like repeat 0.042 4 20.60 99 124
HEAT_EZ HEAT-like repeat 0.1 4 27.00 103 121
HEAT_2 HEAT repeats 0.0011 10 27.70 103 165
HEAT_2 HEAT repeats 0.00048 11 27.70 103 202
HEAT HEAT repeat 0.023 6 23.50 104 128
V-ATPase_H_C V-ATPase subunit H 6.3E-05 13 20.80 104 173
RTP1_C1 Required for nuclear transport of RNA pol II C-terminus 1 0.67 0 25.90 106 148
Adaptin_N Adaptin N terminal region 5.3E-06 15 20.30 106 290
MMS19_N NER and RNAPII transcription protein n terminal 4.8E-05 13 21.40 106 214
DUF3361 Domain of unknown function (DUF3361) 0.00077 10 27.20 107 172
Metal_resist Heavy-metal resistance 0.81 0 29.10 111 144
HEAT_EZ HEAT-like repeat 1.9E-06 19 27.00 114 169
Atx10homo_assoc Spinocerebellar ataxia type 10 protein domain 7.1E-05 13 22.40 116 174
Arm Armadillo/beta-catenin-like repeat 0.012 6 20.60 134 169
HEAT HEAT repeat 0.03 5 23.50 143 171
RTP1_C1 Required for nuclear transport of RNA pol II C-terminus 1 0.0052 7 25.90 152 217
MMS19_N NER and RNAPII transcription protein n terminal 0.09 2 21.40 189 263
Arm Armadillo/beta-catenin-like repeat 0.56 1 20.60 189 211
DUF3361 Domain of unknown function (DUF3361) 0.1 3 27.20 199 247
V-ATPase_H_C V-ATPase subunit H 0.00059 10 20.80 202 251
Arm Armadillo/beta-catenin-like repeat 0.00097 10 20.60 231 255
HEAT HEAT repeat 0.00054 11 23.50 231 254
HEAT_2 HEAT repeats 0.011 6 27.70 231 255
V-ATPase_H_N V-ATPase subunit H 0.81 -1 20.10 231 263
RTP1_C1 Required for nuclear transport of RNA pol II C-terminus 1 0.45 1 25.90 231 264
HEAT_EZ HEAT-like repeat 0.053 4 27.00 234 249
SIL1 Nucleotide exchange factor SIL1 0.27 1 35.50 236 275
Enkurin Calmodulin-binding 0.92 0 23.60 270 293
DUF438 Family of unknown function (DUF438) 0.83 0 25.00 284 296

363

V-ATPase_H_N
Fes1
V-ATPase_H_C
Metal_resist
Enkurin
DUF438
SIL1
RICTOR_N
Arm
HEAT_EZ
HEAT_2
HEAT_2
HEAT
V-ATPase_H_C
RTP1_C1
Adaptin_N
MMS19_N
DUF3361
Metal_resist
HEAT_EZ
Atx10homo_assoc
Arm
HEAT
RTP1_C1
MMS19_N
Arm
DUF3361
V-ATPase_H_C
Arm
HEAT
HEAT_2
V-ATPase_H_N
RTP1_C1
HEAT_EZ
SIL1
Enkurin
DUF438

References:

DUF438

Enkurin

Fes1
12052876 Nucleotide exchange factor for the yeast Hsp70 molecular chaperone Ssa1p. Mol Cell Biol. 2002;22:4677-4689.

HEAT_EZ

Arm
9298899 Three-dimensional structure of the armadillo repeat region of beta-catenin. Cell 1997;90:871-882.
8573337 Signal transduction of beta-catenin. Curr Opin Cell Biol 1995;7:634-640.
9309175 Armadillo and dTCF: a marriage made in the nucleus. Curr Opin Genet Dev 1997;7:459-466.
8259519 Association of the APC tumor suppressor protein with catenins. Science 1993;262:1734-1737.
8259518 Association of the APC gene product with beta-catenin. Science 1993;262:1731-1734.
2261639 The segment polarity gene armadillo encodes a functionally modular protein that is the Drosophila homolog of human plakoglobin. Cell 1990;63:1167-1176.

Adaptin_N
9261055 Linking cargo to vesicle formation: receptor tail interactions with coat proteins. Curr Opin Cell Biol 1997;9:488-495.
2495531 Structural and functional division into two domains of the large (100- to 115-kDa)chains of the clathrin-associated protein complex AP-2. Proc Natl Acad Sci U S A 1989;86:2612-2616.

RICTOR_N

Atx10homo_assoc
15201271 Ataxin-10, the spinocerebellar ataxia type 10 neurodegenerative disorder protein, is essential for survival of cerebellar neurons. J Biol Chem. 2004;279:35542-35550.

MMS19_N
11328871 Cloning the human and mouse MMS19 genes and functional complementation of a yeast mms19 deletion mutant. Nucleic Acids Res. 2001;29:1884-1891.

DUF3361

HEAT
7550332 HEAT repeats in the Huntington's disease protein. Nat Genet 1995;11:115-116.
9989501 The structure of the protein phosphatase 2A PR65/A subunit reveals the conformation of its 15 tandemly repeated HEAT motifs. Cell 1999;96:99-110.

V-ATPase_H_C
10954728 Regulation of yeast ectoapyrase ynd1p activity by activator subunit Vma13p of vacuolar H+-ATPase. J Biol Chem 2000;275:35592-35599.
18708638 Functional characterization of the N-terminal domain of subunit H (Vma13p) of the yeast vacuolar ATPase. J Biol Chem. 2008; [Epub ahead of print]
16141210 Structural and functional separation of the N- and C-terminal domains of the yeast V-ATPase subunit H. J Biol Chem. 2005;280:36978-36985.

SIL1

HEAT_2

V-ATPase_H_N
10954728 Regulation of yeast ectoapyrase ynd1p activity by activator subunit Vma13p of vacuolar H+-ATPase. J Biol Chem 2000;275:35592-35599.
18708638 Functional characterization of the N-terminal domain of subunit H (Vma13p) of the yeast vacuolar ATPase. J Biol Chem. 2008; [Epub ahead of print]
16141210 Structural and functional separation of the N- and C-terminal domains of the yeast V-ATPase subunit H. J Biol Chem. 2005;280:36978-36985.

Metal_resist

RTP1_C1

Domain	Description	Evalue	Bits	GA	Start	End
V-ATPase_H_N	V-ATPase subunit H	8.3E-05	12	20.10	6	197
Fes1	Nucleotide exchange factor Fes1	7.8E-12	36	21.40	10	95
V-ATPase_H_C	V-ATPase subunit H	0.0009	10	20.80	10	129
Metal_resist	Heavy-metal resistance	0.00018	12	29.10	22	91
Enkurin	Calmodulin-binding	0.0019	9	23.60	24	63
DUF438	Family of unknown function (DUF438)	0.0011	9	25.00	61	80
SIL1	Nucleotide exchange factor SIL1	1.1E-08	25	35.50	72	217
RICTOR_N	Rapamycin-insensitive companion of mTOR, N-term	2.7E-05	13	28.50	96	212
Arm	Armadillo/beta-catenin-like repeat	0.042	4	20.60	99	124
HEAT_EZ	HEAT-like repeat	0.1	4	27.00	103	121
HEAT_2	HEAT repeats	0.0011	10	27.70	103	165
HEAT_2	HEAT repeats	0.00048	11	27.70	103	202
HEAT	HEAT repeat	0.023	6	23.50	104	128
V-ATPase_H_C	V-ATPase subunit H	6.3E-05	13	20.80	104	173
RTP1_C1	Required for nuclear transport of RNA pol II C-terminus 1	0.67	0	25.90	106	148
Adaptin_N	Adaptin N terminal region	5.3E-06	15	20.30	106	290
MMS19_N	NER and RNAPII transcription protein n terminal	4.8E-05	13	21.40	106	214
DUF3361	Domain of unknown function (DUF3361)	0.00077	10	27.20	107	172
Metal_resist	Heavy-metal resistance	0.81	0	29.10	111	144
HEAT_EZ	HEAT-like repeat	1.9E-06	19	27.00	114	169
Atx10homo_assoc	Spinocerebellar ataxia type 10 protein domain	7.1E-05	13	22.40	116	174
Arm	Armadillo/beta-catenin-like repeat	0.012	6	20.60	134	169
HEAT	HEAT repeat	0.03	5	23.50	143	171
RTP1_C1	Required for nuclear transport of RNA pol II C-terminus 1	0.0052	7	25.90	152	217
MMS19_N	NER and RNAPII transcription protein n terminal	0.09	2	21.40	189	263
Arm	Armadillo/beta-catenin-like repeat	0.56	1	20.60	189	211
DUF3361	Domain of unknown function (DUF3361)	0.1	3	27.20	199	247
V-ATPase_H_C	V-ATPase subunit H	0.00059	10	20.80	202	251
Arm	Armadillo/beta-catenin-like repeat	0.00097	10	20.60	231	255
HEAT	HEAT repeat	0.00054	11	23.50	231	254
HEAT_2	HEAT repeats	0.011	6	27.70	231	255
V-ATPase_H_N	V-ATPase subunit H	0.81	-1	20.10	231	263
RTP1_C1	Required for nuclear transport of RNA pol II C-terminus 1	0.45	1	25.90	231	264
HEAT_EZ	HEAT-like repeat	0.053	4	27.00	234	249
SIL1	Nucleotide exchange factor SIL1	0.27	1	35.50	236	275
Enkurin	Calmodulin-binding	0.92	0	23.60	270	293
DUF438	Family of unknown function (DUF438)	0.83	0	25.00	284	296