c2pfam

AT3G14420.1 :

Domain Description Evalue Bits GA Start End
FMN_dh FMN-dependent dehydrogenase 0 461 22.00 13 355
PA PA domain 0.62 0 21.30 90 104
PA PA domain 0.51 0 21.30 141 157
DUF561 Protein of unknown function (DUF561) 0.001 8 21.60 179 252
DHO_dh Dihydroorotate dehydrogenase 0.0047 6 20.30 205 248
TMP-TENI Thiamine monophosphate synthase/TENI 0.0018 7 20.80 210 252
ThiG Thiazole biosynthesis protein ThiG 0.0071 5 19.90 217 262
DUF561 Protein of unknown function (DUF561) 0.00026 10 21.60 219 277
His_biosynth Histidine biosynthesis protein 0.37 -1 22.90 223 261
NMO Nitronate monooxygenase 7E-09 25 28.00 232 342
PA PA domain 0.00017 11 21.30 235 263
DUF561 Protein of unknown function (DUF561) 0.0003 9 21.60 257 311
TMP-TENI Thiamine monophosphate synthase/TENI 0.041 3 20.80 263 307
DHO_dh Dihydroorotate dehydrogenase 3.8E-06 16 20.30 264 313
IMPDH IMP dehydrogenase / GMP reductase domain 1.5E-09 27 24.00 264 311
His_biosynth Histidine biosynthesis protein 3.5E-06 16 22.90 265 312
ThiG Thiazole biosynthesis protein ThiG 4.2E-05 12 19.90 273 310
Glu_synthase Conserved region in glutamate synthase 5.7E-07 18 19.80 276 315
IMPDH IMP dehydrogenase / GMP reductase domain 0.56 -2 24.00 322 352

367

FMN_dh
PA
PA
DUF561
DHO_dh
TMP-TENI
ThiG
DUF561
His_biosynth
NMO
PA
DUF561
TMP-TENI
DHO_dh
IMPDH
His_biosynth
ThiG
Glu_synthase
IMPDH

References:

Glu_synthase
8923741 Sequence of the GLT1 gene from Saccharomyces cerevisiae reveals the domain structure of yeast glutamate synthase. Yeast 1996;12:1359-1366.

DUF561

His_biosynth
9332345 Paralogous histidine biosynthetic genes: evolutionary analysis of the Saccharomyces cerevisiae HIS6 and HIS7 genes. Gene 1997;197:9-17.
8028028 The evolution of the histidine biosynthetic genes in prokaryotes: a common ancestor for the hisA and hisF genes. J Mol Evol 1994;38:489-495.
8028028 The evolution of the histidine biosynthetic genes in prokaryotes: a common ancestor for the hisA and hisF genes. J Mol Evol 1994;38:489-495.
11054297 Homology among (betaalpha)(8) barrels: implications for the evolution of metabolic pathways. J Mol Biol 2000;303:627-641.

NMO

ThiG
9371431 Expression of thiamin biosynthetic genes (thiCOGE) and production of symbiotic terminal oxidase cbb3 in Rhizobium etli. J Bacteriol 1997;179:6887-6893.

DHO_dh
9655329 The crystal structure of Lactococcus lactis dihydroorotate dehydrogenase A complexed with the enzyme reaction product throws light on its enzymatic function. Protein Sci 1998;7:1269-1279.

IMPDH
9271497 Crystal structure of Tritrichomonas foetus inosine-5'-monophosphate dehydrogenase and the enzyme-product complex. Biochemistry 1997;36:10666-10674.
10200156 Characteristics and crystal structure of bacterial inosine-5'-monophosphate dehydrogenase. Biochemistry 1999;38:4691-4700.

FMN_dh
2681790 Refined structure of spinach glycolate oxidase at 2 A resolution. J Mol Biol 1989;209:151-166.
2329585 Molecular structure of flavocytochrome b2 at 2.4 A resolution. J Mol Biol 1990;212:837-863.

TMP-TENI
9139923 Characterization of the Bacillus subtilis thiC operon involved in thiamine biosynthesis. J Bacteriol 1997;179:3030-3035.

PA
11246007 The protease-associated domain: a homology domain associated with multiple classes of proteases. Trends Biochem Sci 2001;26:147-148.

Domain	Description	Evalue	Bits	GA	Start	End
FMN_dh	FMN-dependent dehydrogenase	0	461	22.00	13	355
PA	PA domain	0.62	0	21.30	90	104
PA	PA domain	0.51	0	21.30	141	157
DUF561	Protein of unknown function (DUF561)	0.001	8	21.60	179	252
DHO_dh	Dihydroorotate dehydrogenase	0.0047	6	20.30	205	248
TMP-TENI	Thiamine monophosphate synthase/TENI	0.0018	7	20.80	210	252
ThiG	Thiazole biosynthesis protein ThiG	0.0071	5	19.90	217	262
DUF561	Protein of unknown function (DUF561)	0.00026	10	21.60	219	277
His_biosynth	Histidine biosynthesis protein	0.37	-1	22.90	223	261
NMO	Nitronate monooxygenase	7E-09	25	28.00	232	342
PA	PA domain	0.00017	11	21.30	235	263
DUF561	Protein of unknown function (DUF561)	0.0003	9	21.60	257	311
TMP-TENI	Thiamine monophosphate synthase/TENI	0.041	3	20.80	263	307
DHO_dh	Dihydroorotate dehydrogenase	3.8E-06	16	20.30	264	313
IMPDH	IMP dehydrogenase / GMP reductase domain	1.5E-09	27	24.00	264	311
His_biosynth	Histidine biosynthesis protein	3.5E-06	16	22.90	265	312
ThiG	Thiazole biosynthesis protein ThiG	4.2E-05	12	19.90	273	310
Glu_synthase	Conserved region in glutamate synthase	5.7E-07	18	19.80	276	315
IMPDH	IMP dehydrogenase / GMP reductase domain	0.56	-2	24.00	322	352