c2pfam

AT3G27960.1 :

Domain Description Evalue Bits GA Start End
TPR_12 Tetratricopeptide repeat 1.5E-06 19 30.10 170 229
DUF3856 Domain of Unknown Function (DUF3856) 0.0022 9 27.00 170 229
TPR_MalT MalT-like TPR region 1.2E-05 15 27.00 172 323
Paf67 RNA polymerase I-associated factor PAF67 0.63 0 19.90 198 226
TPR_17 Tetratricopeptide repeat 0.45 2 24.40 199 219
TPR_10 Tetratricopeptide repeat 1.6E-05 16 27.50 201 229
TPR_7 Tetratricopeptide repeat 5.7E-05 14 27.90 202 229
TPR_4 Tetratricopeptide repeat 0.0095 8 22.00 202 225
TPR_2 Tetratricopeptide repeat 0.00038 11 22.40 203 229
TPR_8 Tetratricopeptide repeat 0.00026 12 25.70 203 229
TPR_14 Tetratricopeptide repeat 0.019 7 23.50 205 228
TPR_19 Tetratricopeptide repeat 0.2 3 25.00 206 226
TPR_16 Tetratricopeptide repeat 0.065 5 32.70 206 227
TPR_1 Tetratricopeptide repeat 0.00066 10 20.40 206 229
TPR_9 Tetratricopeptide repeat 0.21 3 35.00 207 228
TPR_11 TPR repeat 0.25 2 26.80 209 229
TPR_8 Tetratricopeptide repeat 0.0011 10 25.70 246 275
TPR_1 Tetratricopeptide repeat 0.02 6 20.40 246 273
TPR_7 Tetratricopeptide repeat 0.56 1 27.90 247 271
TPR_12 Tetratricopeptide repeat 5.8E-09 27 30.10 247 316
TPR_10 Tetratricopeptide repeat 0.017 6 27.50 248 279
TPR_11 TPR repeat 0.78 0 26.80 250 273
MIT MIT (microtubule interacting and transport) domain 0.59 1 28.30 257 284
Foie-gras_1 Foie gras liver health family 1 0.18 2 23.10 283 311
TPR_19 Tetratricopeptide repeat 0.00063 11 25.00 284 318
14-3-3 14-3-3 protein 0.51 1 20.70 285 315
TPR_2 Tetratricopeptide repeat 0.024 6 22.40 286 317
TPR_7 Tetratricopeptide repeat 0.0096 7 27.90 287 317
TPR_10 Tetratricopeptide repeat 0.0023 9 27.50 288 317
TPR_1 Tetratricopeptide repeat 0.0028 8 20.40 290 317
TPR_14 Tetratricopeptide repeat 0.00047 12 23.50 290 323
Fis1_TPR_C Fis1 C-terminal tetratricopeptide repeat 6.9E-05 14 25.30 290 321
TPR_21 Tetratricopeptide repeat-like domain 4.9E-05 14 25.50 291 420
DUF3856 Domain of Unknown Function (DUF3856) 0.09 4 27.00 292 337
SPO22 Meiosis protein SPO22/ZIP4 like 0.2 2 25.40 292 312
TPR_12 Tetratricopeptide repeat 0.02 6 30.10 329 352
TPR_1 Tetratricopeptide repeat 0.025 5 20.40 334 352
TPR_7 Tetratricopeptide repeat 0.013 7 27.90 335 355
TPR_8 Tetratricopeptide repeat 0.053 5 25.70 335 352
TPR_2 Tetratricopeptide repeat 0.0049 8 22.40 335 352
TPR_MalT MalT-like TPR region 3.3E-10 30 27.00 339 519
MIT MIT (microtubule interacting and transport) domain 0.062 4 28.30 339 355
TPR_11 TPR repeat 0.084 3 26.80 340 352
TPR_19 Tetratricopeptide repeat 0.011 7 25.00 342 397
Paf67 RNA polymerase I-associated factor PAF67 0.00076 9 19.90 343 407
SPO22 Meiosis protein SPO22/ZIP4 like 0.052 4 25.40 362 423
TPR_12 Tetratricopeptide repeat 8E-11 33 30.10 367 442
Foie-gras_1 Foie gras liver health family 1 0.87 0 23.10 368 398
DUF3856 Domain of Unknown Function (DUF3856) 0.00067 10 27.00 372 411
TPR_7 Tetratricopeptide repeat 0.00048 11 27.90 373 398
TPR_1 Tetratricopeptide repeat 2.7E-07 21 20.40 373 398
TPR_8 Tetratricopeptide repeat 4.7E-06 18 25.70 374 397
TPR_2 Tetratricopeptide repeat 2E-06 19 22.40 375 398
TPR_16 Tetratricopeptide repeat 0.019 7 32.70 375 400
TPR_10 Tetratricopeptide repeat 0.039 5 27.50 375 407
TPR_6 Tetratricopeptide repeat 0.099 4 26.30 375 396
TPR_11 TPR repeat 5.2E-05 14 26.80 376 397
TPR_14 Tetratricopeptide repeat 0.00055 12 23.50 376 403
DUF2225 Uncharacterized protein conserved in bacteria (DUF2225) 4.7E-07 20 20.60 378 442
TPR_19 Tetratricopeptide repeat 0.044 5 25.00 385 429
MIT MIT (microtubule interacting and transport) domain 0.0069 7 28.30 385 404
TPR_12 Tetratricopeptide repeat 1.6E-10 32 30.10 410 484
TPR_10 Tetratricopeptide repeat 0.16 3 27.50 411 441
TPR_1 Tetratricopeptide repeat 0.00032 11 20.40 411 440
TPR_2 Tetratricopeptide repeat 0.047 5 22.40 411 441
TPR_17 Tetratricopeptide repeat 0.084 4 24.40 411 429
TPR_8 Tetratricopeptide repeat 2.4E-05 15 25.70 413 441
TPR_7 Tetratricopeptide repeat 0.005 8 27.90 414 440
TPR_6 Tetratricopeptide repeat 0.26 3 26.30 414 441
TPR_21 Tetratricopeptide repeat-like domain 1 0 25.50 448 480
SPO22 Meiosis protein SPO22/ZIP4 like 0.13 2 25.40 451 527
DUF2225 Uncharacterized protein conserved in bacteria (DUF2225) 0.0044 7 20.60 452 521
TPR_12 Tetratricopeptide repeat 4.3E-08 24 30.10 454 522
DUF3856 Domain of Unknown Function (DUF3856) 0.62 1 27.00 455 493
TPR_2 Tetratricopeptide repeat 0.00012 13 22.40 458 485
TPR_8 Tetratricopeptide repeat 0.00057 11 25.70 460 485
TPR_10 Tetratricopeptide repeat 9E-06 16 27.50 460 487
TPR_9 Tetratricopeptide repeat 0.052 5 35.00 461 502
DUF4810 Domain of unknown function (DUF4810) 0.00073 11 34.70 463 528
TPR_6 Tetratricopeptide repeat 0.0055 8 26.30 463 486
TPR_7 Tetratricopeptide repeat 0.0023 9 27.90 463 482
TPR_1 Tetratricopeptide repeat 3.4E-05 14 20.40 463 484
TPR_11 TPR repeat 0.0023 9 26.80 463 487
TPR_16 Tetratricopeptide repeat 0.018 7 32.70 464 488
TPR_19 Tetratricopeptide repeat 0.011 7 25.00 464 486
TPR_14 Tetratricopeptide repeat 0.0035 9 23.50 464 486
Foie-gras_1 Foie gras liver health family 1 0.0012 9 23.10 465 529
TPR_12 Tetratricopeptide repeat 8.1E-06 17 30.10 498 563
Paf67 RNA polymerase I-associated factor PAF67 0.89 -1 19.90 500 527
TPR_1 Tetratricopeptide repeat 0.44 1 20.40 505 523
TPR_2 Tetratricopeptide repeat 0.35 2 22.40 506 526
TPR_6 Tetratricopeptide repeat 0.13 4 26.30 506 528
MIT MIT (microtubule interacting and transport) domain 0.29 2 28.30 509 526
TPR_MalT MalT-like TPR region 7.3E-05 13 27.00 538 633
TPR_12 Tetratricopeptide repeat 4.6E-13 40 30.10 538 603
TPR_10 Tetratricopeptide repeat 1.6E-06 19 27.50 539 577
TPR_1 Tetratricopeptide repeat 0.78 1 20.40 539 565
TPR_2 Tetratricopeptide repeat 0.055 5 22.40 539 564
14-3-3 14-3-3 protein 0.00025 11 20.70 551 632
TPR_19 Tetratricopeptide repeat 3.9E-05 15 25.00 554 603
DUF3856 Domain of Unknown Function (DUF3856) 0.59 1 27.00 559 601
TPR_16 Tetratricopeptide repeat 0.14 4 32.70 573 603
TPR_10 Tetratricopeptide repeat 3.2E-09 27 27.50 578 619
TPR_4 Tetratricopeptide repeat 0.037 6 22.00 580 603
TPR_17 Tetratricopeptide repeat 0.11 4 24.40 581 600
TPR_1 Tetratricopeptide repeat 0.00057 11 20.40 581 600
TPR_2 Tetratricopeptide repeat 0.01 7 22.40 581 603
TPR_8 Tetratricopeptide repeat 0.0011 10 25.70 581 603
TPR_7 Tetratricopeptide repeat 7.7E-05 14 27.90 582 605
TPR_14 Tetratricopeptide repeat 0.091 5 23.50 583 603
TPR_6 Tetratricopeptide repeat 0.18 4 26.30 585 604

663

TPR_12
DUF3856
TPR_MalT
Paf67
TPR_17
TPR_10
TPR_7
TPR_4
TPR_2
TPR_8
TPR_14
TPR_19
TPR_16
TPR_1
TPR_9
TPR_11
TPR_8
TPR_1
TPR_7
TPR_12
TPR_10
TPR_11
MIT
Foie-gras_1
TPR_19
14-3-3
TPR_2
TPR_7
TPR_10
TPR_1
TPR_14
Fis1_TPR_C
TPR_21
DUF3856
SPO22
TPR_12
TPR_1
TPR_7
TPR_8
TPR_2
TPR_MalT
MIT
TPR_11
TPR_19
Paf67
SPO22
TPR_12
Foie-gras_1
DUF3856
TPR_7
TPR_1
TPR_8
TPR_2
TPR_16
TPR_10
TPR_6
TPR_11
TPR_14
DUF2225
TPR_19
MIT
TPR_12
TPR_10
TPR_1
TPR_2
TPR_17
TPR_8
TPR_7
TPR_6
TPR_21
SPO22
DUF2225
TPR_12
DUF3856
TPR_2
TPR_8
TPR_10
TPR_9
DUF4810
TPR_6
TPR_7
TPR_1
TPR_11
TPR_16
TPR_19
TPR_14
Foie-gras_1
TPR_12
Paf67
TPR_1
TPR_2
TPR_6
MIT
TPR_MalT
TPR_12
TPR_10
TPR_1
TPR_2
14-3-3
TPR_19
DUF3856
TPR_16
TPR_10
TPR_4
TPR_17
TPR_1
TPR_2
TPR_8
TPR_7
TPR_14
TPR_6

References:

TPR_7

14-3-3
7603573 Structure of a 14-3-3 protein and implications for coordination of multiple signalling pathways. Nature 1995;376:188-191.
7603574 Crystal structure of the zeta isoform of the 14-3-3 protein. Nature 1995;376:191-194.
8601312 Interaction of 14-3-3 with signaling proteins is mediated by the recognition of phosphoserine. Cell 1996;84:889-897.
9280296 The 14-3-3 protein binds its target proteins with a common site located towards the C-terminus. FEBS Lett 1997;413:273-276.
8798343 Molecular evolution of the 14-3-3 protein family. J Mol Evol 1996;43:384-398.
8684458 Function of 14-3-3 proteins. Nature 1996;382:308-308.
12184815 The 14-3-3s. Genome Biol 2002;3:REVIEWS3010.

TPR_4

TPR_2
7667876 Tetratrico peptide repeat interactions: to TPR or not to TPR? Trends Biochem Sci 1995;20:257-259.
9482716 The structure of the tetratricopeptide repeats of protein phosphatase 5: implications for TPR-mediated protein-protein interactions. EMBO J 1998;17:1192-1199.

DUF3856

TPR_19

MIT
11085978 Identification and characterization of SNX15, a novel sorting nexin involved in protein trafficking. J Biol Chem 2001;276:5074-5084.
16193069 Structural and mechanistic studies of VPS4 proteins. EMBO J. 2005;24:3658-3669.
16174732 Structure and ESCRT-III protein interactions of the MIT domain of human VPS4A. Proc Natl Acad Sci U S A. 2005;102:13813-13818.

TPR_17

TPR_16

TPR_14

TPR_12

TPR_11

TPR_10

Fis1_TPR_C

Paf67
11592397 PAF67, a novel protein that is associated with the initiation-competent form of RNA polymerase I. Biol Chem. 2001;382:1163-1170.

TPR_21

DUF2225

Foie-gras_1
16000385 A genetic screen in zebrafish identifies the mutants vps18, nf2 and foie gras as models of liver disease. Development. 2005;132:3561-3572.

SPO22
16314568 Bioinformatic analyses implicate the collaborating meiotic crossover/chiasma proteins Zip2, Zip3, and Spo22/Zip4 in ubiquitin labeling. Proc Natl Acad Sci U S A. 2005;102:17594-17599.
18369460 ZIP4H (TEX11) Deficiency in the Mouse Impairs Meiotic Double Strand Break Repair and the Regulation of Crossing Over. PLoS Genet. 2008;4:e1000042.
16740482 The meiosis-specific zip4 protein regulates crossover distribution by promoting synaptonemal complex formation together with zip2. Dev Cell. 2006;10:809-819.

DUF4810

TPR_6

TPR_1
7667876 Tetratrico peptide repeat interactions: to TPR or not to TPR? Trends Biochem Sci 1995;20:257-259.
9482716 The structure of the tetratricopeptide repeats of protein phosphatase 5: implications for TPR-mediated protein-protein interactions. EMBO J 1998;17:1192-1199.

TPR_MalT

TPR_9

TPR_8

Domain	Description	Evalue	Bits	GA	Start	End
TPR_12	Tetratricopeptide repeat	1.5E-06	19	30.10	170	229
DUF3856	Domain of Unknown Function (DUF3856)	0.0022	9	27.00	170	229
TPR_MalT	MalT-like TPR region	1.2E-05	15	27.00	172	323
Paf67	RNA polymerase I-associated factor PAF67	0.63	0	19.90	198	226
TPR_17	Tetratricopeptide repeat	0.45	2	24.40	199	219
TPR_10	Tetratricopeptide repeat	1.6E-05	16	27.50	201	229
TPR_7	Tetratricopeptide repeat	5.7E-05	14	27.90	202	229
TPR_4	Tetratricopeptide repeat	0.0095	8	22.00	202	225
TPR_2	Tetratricopeptide repeat	0.00038	11	22.40	203	229
TPR_8	Tetratricopeptide repeat	0.00026	12	25.70	203	229
TPR_14	Tetratricopeptide repeat	0.019	7	23.50	205	228
TPR_19	Tetratricopeptide repeat	0.2	3	25.00	206	226
TPR_16	Tetratricopeptide repeat	0.065	5	32.70	206	227
TPR_1	Tetratricopeptide repeat	0.00066	10	20.40	206	229
TPR_9	Tetratricopeptide repeat	0.21	3	35.00	207	228
TPR_11	TPR repeat	0.25	2	26.80	209	229
TPR_8	Tetratricopeptide repeat	0.0011	10	25.70	246	275
TPR_1	Tetratricopeptide repeat	0.02	6	20.40	246	273
TPR_7	Tetratricopeptide repeat	0.56	1	27.90	247	271
TPR_12	Tetratricopeptide repeat	5.8E-09	27	30.10	247	316
TPR_10	Tetratricopeptide repeat	0.017	6	27.50	248	279
TPR_11	TPR repeat	0.78	0	26.80	250	273
MIT	MIT (microtubule interacting and transport) domain	0.59	1	28.30	257	284
Foie-gras_1	Foie gras liver health family 1	0.18	2	23.10	283	311
TPR_19	Tetratricopeptide repeat	0.00063	11	25.00	284	318
14-3-3	14-3-3 protein	0.51	1	20.70	285	315
TPR_2	Tetratricopeptide repeat	0.024	6	22.40	286	317
TPR_7	Tetratricopeptide repeat	0.0096	7	27.90	287	317
TPR_10	Tetratricopeptide repeat	0.0023	9	27.50	288	317
TPR_1	Tetratricopeptide repeat	0.0028	8	20.40	290	317
TPR_14	Tetratricopeptide repeat	0.00047	12	23.50	290	323
Fis1_TPR_C	Fis1 C-terminal tetratricopeptide repeat	6.9E-05	14	25.30	290	321
TPR_21	Tetratricopeptide repeat-like domain	4.9E-05	14	25.50	291	420
DUF3856	Domain of Unknown Function (DUF3856)	0.09	4	27.00	292	337
SPO22	Meiosis protein SPO22/ZIP4 like	0.2	2	25.40	292	312
TPR_12	Tetratricopeptide repeat	0.02	6	30.10	329	352
TPR_1	Tetratricopeptide repeat	0.025	5	20.40	334	352
TPR_7	Tetratricopeptide repeat	0.013	7	27.90	335	355
TPR_8	Tetratricopeptide repeat	0.053	5	25.70	335	352
TPR_2	Tetratricopeptide repeat	0.0049	8	22.40	335	352
TPR_MalT	MalT-like TPR region	3.3E-10	30	27.00	339	519
MIT	MIT (microtubule interacting and transport) domain	0.062	4	28.30	339	355
TPR_11	TPR repeat	0.084	3	26.80	340	352
TPR_19	Tetratricopeptide repeat	0.011	7	25.00	342	397
Paf67	RNA polymerase I-associated factor PAF67	0.00076	9	19.90	343	407
SPO22	Meiosis protein SPO22/ZIP4 like	0.052	4	25.40	362	423
TPR_12	Tetratricopeptide repeat	8E-11	33	30.10	367	442
Foie-gras_1	Foie gras liver health family 1	0.87	0	23.10	368	398
DUF3856	Domain of Unknown Function (DUF3856)	0.00067	10	27.00	372	411
TPR_7	Tetratricopeptide repeat	0.00048	11	27.90	373	398
TPR_1	Tetratricopeptide repeat	2.7E-07	21	20.40	373	398
TPR_8	Tetratricopeptide repeat	4.7E-06	18	25.70	374	397
TPR_2	Tetratricopeptide repeat	2E-06	19	22.40	375	398
TPR_16	Tetratricopeptide repeat	0.019	7	32.70	375	400
TPR_10	Tetratricopeptide repeat	0.039	5	27.50	375	407
TPR_6	Tetratricopeptide repeat	0.099	4	26.30	375	396
TPR_11	TPR repeat	5.2E-05	14	26.80	376	397
TPR_14	Tetratricopeptide repeat	0.00055	12	23.50	376	403
DUF2225	Uncharacterized protein conserved in bacteria (DUF2225)	4.7E-07	20	20.60	378	442
TPR_19	Tetratricopeptide repeat	0.044	5	25.00	385	429
MIT	MIT (microtubule interacting and transport) domain	0.0069	7	28.30	385	404
TPR_12	Tetratricopeptide repeat	1.6E-10	32	30.10	410	484
TPR_10	Tetratricopeptide repeat	0.16	3	27.50	411	441
TPR_1	Tetratricopeptide repeat	0.00032	11	20.40	411	440
TPR_2	Tetratricopeptide repeat	0.047	5	22.40	411	441
TPR_17	Tetratricopeptide repeat	0.084	4	24.40	411	429
TPR_8	Tetratricopeptide repeat	2.4E-05	15	25.70	413	441
TPR_7	Tetratricopeptide repeat	0.005	8	27.90	414	440
TPR_6	Tetratricopeptide repeat	0.26	3	26.30	414	441
TPR_21	Tetratricopeptide repeat-like domain	1	0	25.50	448	480
SPO22	Meiosis protein SPO22/ZIP4 like	0.13	2	25.40	451	527
DUF2225	Uncharacterized protein conserved in bacteria (DUF2225)	0.0044	7	20.60	452	521
TPR_12	Tetratricopeptide repeat	4.3E-08	24	30.10	454	522
DUF3856	Domain of Unknown Function (DUF3856)	0.62	1	27.00	455	493
TPR_2	Tetratricopeptide repeat	0.00012	13	22.40	458	485
TPR_8	Tetratricopeptide repeat	0.00057	11	25.70	460	485
TPR_10	Tetratricopeptide repeat	9E-06	16	27.50	460	487
TPR_9	Tetratricopeptide repeat	0.052	5	35.00	461	502
DUF4810	Domain of unknown function (DUF4810)	0.00073	11	34.70	463	528
TPR_6	Tetratricopeptide repeat	0.0055	8	26.30	463	486
TPR_7	Tetratricopeptide repeat	0.0023	9	27.90	463	482
TPR_1	Tetratricopeptide repeat	3.4E-05	14	20.40	463	484
TPR_11	TPR repeat	0.0023	9	26.80	463	487
TPR_16	Tetratricopeptide repeat	0.018	7	32.70	464	488
TPR_19	Tetratricopeptide repeat	0.011	7	25.00	464	486
TPR_14	Tetratricopeptide repeat	0.0035	9	23.50	464	486
Foie-gras_1	Foie gras liver health family 1	0.0012	9	23.10	465	529
TPR_12	Tetratricopeptide repeat	8.1E-06	17	30.10	498	563
Paf67	RNA polymerase I-associated factor PAF67	0.89	-1	19.90	500	527
TPR_1	Tetratricopeptide repeat	0.44	1	20.40	505	523
TPR_2	Tetratricopeptide repeat	0.35	2	22.40	506	526
TPR_6	Tetratricopeptide repeat	0.13	4	26.30	506	528
MIT	MIT (microtubule interacting and transport) domain	0.29	2	28.30	509	526
TPR_MalT	MalT-like TPR region	7.3E-05	13	27.00	538	633
TPR_12	Tetratricopeptide repeat	4.6E-13	40	30.10	538	603
TPR_10	Tetratricopeptide repeat	1.6E-06	19	27.50	539	577
TPR_1	Tetratricopeptide repeat	0.78	1	20.40	539	565
TPR_2	Tetratricopeptide repeat	0.055	5	22.40	539	564
14-3-3	14-3-3 protein	0.00025	11	20.70	551	632
TPR_19	Tetratricopeptide repeat	3.9E-05	15	25.00	554	603
DUF3856	Domain of Unknown Function (DUF3856)	0.59	1	27.00	559	601
TPR_16	Tetratricopeptide repeat	0.14	4	32.70	573	603
TPR_10	Tetratricopeptide repeat	3.2E-09	27	27.50	578	619
TPR_4	Tetratricopeptide repeat	0.037	6	22.00	580	603
TPR_17	Tetratricopeptide repeat	0.11	4	24.40	581	600
TPR_1	Tetratricopeptide repeat	0.00057	11	20.40	581	600
TPR_2	Tetratricopeptide repeat	0.01	7	22.40	581	603
TPR_8	Tetratricopeptide repeat	0.0011	10	25.70	581	603
TPR_7	Tetratricopeptide repeat	7.7E-05	14	27.90	582	605
TPR_14	Tetratricopeptide repeat	0.091	5	23.50	583	603
TPR_6	Tetratricopeptide repeat	0.18	4	26.30	585	604