c2pfam

AT3G57410.1 :

Domain Description Evalue Bits GA Start End
Gelsolin Gelsolin repeat 4.5E-19 56 21.00 29 111
Gelsolin Gelsolin repeat 2.9E-13 38 21.00 153 205
Gelsolin Gelsolin repeat 5.7E-18 53 21.00 270 337
DEP Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) 0.031 3 21.20 287 316
PAC4 Proteasome assembly chaperone 4 0.13 1 31.00 287 316
Gelsolin Gelsolin repeat 3E-14 41 21.00 413 483
DEP Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) 0.045 2 21.20 439 471
Gelsolin Gelsolin repeat 3.9E-12 34 21.00 533 601
DEP Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) 0.17 0 21.20 548 591
PAC4 Proteasome assembly chaperone 4 0.0063 5 31.00 553 609
Gelsolin Gelsolin repeat 4.8E-08 21 21.00 635 713
PAC4 Proteasome assembly chaperone 4 0.16 1 31.00 653 673
DEP Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) 0.14 1 21.20 661 684
VHP Villin headpiece domain 3.5E-18 54 21.70 930 965

965

Gelsolin
Gelsolin
Gelsolin
DEP
PAC4
Gelsolin
DEP
Gelsolin
DEP
PAC4
Gelsolin
PAC4
DEP
VHP

References:

VHP

DEP
8755244 Pleckstrin's repeat performance: a novel domain in G-protein signaling? Trends Biochem Sci 1996;21:245-246.
14614075 The DEP domain determines subcellular targeting of the GTPase activating protein RGS9 in vivo. J Neurosci 2003;23:10175-10181.
14625292 Absence of the RGS9.Gbeta5 GTPase-activating complex in photoreceptors of the R9AP knockout mouse. J Biol Chem 2004;279:1581-1584.
15353129 Characterization of function of three domains in dishevelled-1: DEP domain is responsible for membrane translocation of dishevelled-1. Cell Res. 2004;14:324-330.
15728856 D2 dopamine receptors colocalize regulator of G-protein signaling 9-2 (RGS9-2) via the RGS9 DEP domain, and RGS9 knock-out mice develop dyskinesias associated with dopamine pathways. J Neurosci. 2005;25:2157-2165.
16990133 DEP-domain-mediated regulation of GPCR signaling responses. Cell. 2006;126:1079-1093.
17011483 DEP domains: More than just membrane anchors. Dev Cell. 2006;11:436-438.

Gelsolin
9288746 The crystal structure of plasma gelsolin: implications for actin severing, capping, and nucleation. Cell 1997;90:661-670.
15526166 Gelsolin superfamily proteins: key regulators of cellular functions. Cell Mol Life Sci 2004;61:2614-2623.

PAC4

Domain	Description	Evalue	Bits	GA	Start	End
Gelsolin	Gelsolin repeat	4.5E-19	56	21.00	29	111
Gelsolin	Gelsolin repeat	2.9E-13	38	21.00	153	205
Gelsolin	Gelsolin repeat	5.7E-18	53	21.00	270	337
DEP	Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP)	0.031	3	21.20	287	316
PAC4	Proteasome assembly chaperone 4	0.13	1	31.00	287	316
Gelsolin	Gelsolin repeat	3E-14	41	21.00	413	483
DEP	Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP)	0.045	2	21.20	439	471
Gelsolin	Gelsolin repeat	3.9E-12	34	21.00	533	601
DEP	Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP)	0.17	0	21.20	548	591
PAC4	Proteasome assembly chaperone 4	0.0063	5	31.00	553	609
Gelsolin	Gelsolin repeat	4.8E-08	21	21.00	635	713
PAC4	Proteasome assembly chaperone 4	0.16	1	31.00	653	673
DEP	Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP)	0.14	1	21.20	661	684
VHP	Villin headpiece domain	3.5E-18	54	21.70	930	965