c2pfam

AT3G62150.1 :

Domain Description Evalue Bits GA Start End
Dynamin_N Dynamin family 0.4 2 21.00 19 63
AAA_15 AAA ATPase domain 0.33 2 32.10 25 55
ABC_membrane ABC transporter transmembrane region 0 196 22.00 80 354
AAA_29 P-loop containing region of AAA domain 5.2E-06 18 27.00 420 448
AAA_15 AAA ATPase domain 0.00019 12 32.10 421 472
ABC_tran ABC transporter 1.2E-37 121 23.10 423 570
AAA_7 P-loop containing dynein motor region 0.0074 7 25.80 425 451
Sigma54_activat Sigma-54 interaction domain 0.013 7 20.20 427 456
TsaE Threonylcarbamoyl adenosine biosynthesis protein TsaE 0.057 5 26.60 427 452
DLIC Dynein light intermediate chain (DLIC) 0.21 2 19.30 428 460
AAA_25 AAA domain 0.0043 8 27.00 428 448
AAA_16 AAA ATPase domain 1.6E-06 20 32.60 428 586
DEAD DEAD/DEAH box helicase 0.00051 11 20.60 428 587
AAA_30 AAA domain 0.00017 13 27.00 429 585
KAP_NTPase KAP family P-loop domain 0.0051 7 20.00 429 602
RsgA_GTPase RsgA GTPase 0.00013 13 30.00 430 462
APS_kinase Adenylylsulphate kinase 0.0039 8 20.70 431 468
AAA_22 AAA domain 2.4E-05 16 27.00 432 592
DUF815 Protein of unknown function (DUF815) 0.011 6 20.10 432 475
AAA_24 AAA domain 0.0094 7 27.00 433 453
NACHT NACHT domain 0.016 6 20.40 433 449
G-alpha G-protein alpha subunit 5.9E-05 14 20.10 433 464
Ploopntkinase3 P-loop Nucleotide Kinase3 0.0064 8 27.00 434 457
AAA_5 AAA domain (dynein-related subfamily) 0.0016 10 20.80 434 476
Zeta_toxin Zeta toxin 8.2E-06 17 20.10 434 472
DUF87 Domain of unknown function DUF87 0.0022 9 20.90 434 453
Dynamin_N Dynamin family 0.081 4 21.00 434 448
Roc Ras of Complex, Roc, domain of DAPkinase 0.053 5 27.00 434 456
AAA_33 AAA domain 0.021 6 27.00 434 449
MMR_HSR1 GTPase of unknown function 0.022 6 24.50 434 450
AAA_18 AAA domain 0.019 7 29.40 434 453
PRK Phosphoribulokinase / Uridine kinase family 0.0099 7 20.60 434 456
NTPase_1 NTPase 0.0068 8 23.90 434 475
RNA_helicase RNA helicase 0.11 4 21.50 435 450
AAA_21 AAA domain, putative AbiEii toxin, Type IV TA system 0.0039 8 27.00 435 465
SMC_N RecF/RecN/SMC N terminal domain 2E-06 19 40.00 448 613
ABC_ATPase Predicted ATPase of the ABC class 3.7E-06 17 19.30 515 571
SbcCD_C Putative exonuclease SbcCD, C subunit 0.0015 10 27.00 558 584
FERM_N FERM N-terminal domain 0.2 3 21.10 562 588
ABC_membrane ABC transporter transmembrane region 0 200 22.00 730 1002
DUF2585 Protein of unknown function (DUF2585) 0.00059 11 25.00 792 881
RsgA_GTPase RsgA GTPase 6.6E-05 14 30.00 1069 1102
AAA_29 P-loop containing region of AAA domain 9.5E-06 17 27.00 1070 1097
ABC_tran ABC transporter 4.1E-37 119 23.10 1071 1220
TsaE Threonylcarbamoyl adenosine biosynthesis protein TsaE 0.026 6 26.60 1071 1100
AAA_16 AAA ATPase domain 1.9E-05 16 32.60 1076 1109
DEAD DEAD/DEAH box helicase 0.00037 12 20.60 1076 1237
AAA_7 P-loop containing dynein motor region 0.0031 8 25.80 1076 1105
AAA_25 AAA domain 0.0069 7 27.00 1077 1098
Sigma54_activat Sigma-54 interaction domain 0.056 4 20.20 1077 1102
AAA_15 AAA ATPase domain 0.00051 11 32.10 1077 1107
DLIC Dynein light intermediate chain (DLIC) 0.0019 8 19.30 1078 1109
KAP_NTPase KAP family P-loop domain 0.019 5 20.00 1079 1221
DUF815 Protein of unknown function (DUF815) 0.0011 10 20.10 1080 1137
AAA_24 AAA domain 0.0008 10 27.00 1080 1121
APS_kinase Adenylylsulphate kinase 0.0022 9 20.70 1080 1120
AAA_22 AAA domain 3.2E-06 19 27.00 1081 1236
Zeta_toxin Zeta toxin 0.00031 11 20.10 1081 1120
DUF87 Domain of unknown function DUF87 0.0035 9 20.90 1081 1104
NACHT NACHT domain 0.016 7 20.40 1082 1098
AAA_30 AAA domain 0.0017 9 27.00 1082 1233
SMC_N RecF/RecN/SMC N terminal domain 0.055 4 40.00 1082 1098
Ploopntkinase3 P-loop Nucleotide Kinase3 0.0014 10 27.00 1082 1107
G-alpha G-protein alpha subunit 0.00045 11 20.10 1082 1107
MMR_HSR1 GTPase of unknown function 0.01 7 24.50 1083 1100
PRK Phosphoribulokinase / Uridine kinase family 0.0065 8 20.60 1083 1103
AAA_18 AAA domain 0.011 8 29.40 1083 1102
Dynamin_N Dynamin family 0.022 6 21.00 1083 1101
Roc Ras of Complex, Roc, domain of DAPkinase 0.02 7 27.00 1083 1106
RNA_helicase RNA helicase 0.054 5 21.50 1083 1101
NTPase_1 NTPase 0.15 3 23.90 1083 1100
AAA_33 AAA domain 0.041 5 27.00 1084 1098
AAA_21 AAA domain, putative AbiEii toxin, Type IV TA system 0.0013 10 27.00 1084 1125
AAA_5 AAA domain (dynein-related subfamily) 0.0072 8 20.80 1084 1106
SMC_N RecF/RecN/SMC N terminal domain 1.4E-06 19 40.00 1112 1263
NTPase_1 NTPase 0.68 1 23.90 1170 1255
ABC_ATPase Predicted ATPase of the ABC class 0.0033 8 19.30 1171 1222
SbcCD_C Putative exonuclease SbcCD, C subunit 0.0075 8 27.00 1208 1234
FERM_N FERM N-terminal domain 0.12 4 21.10 1212 1238

1296

Dynamin_N
AAA_15
ABC_membrane
AAA_29
AAA_15
ABC_tran
AAA_7
Sigma54_activat
TsaE
DLIC
AAA_25
AAA_16
DEAD
AAA_30
KAP_NTPase
RsgA_GTPase
APS_kinase
AAA_22
DUF815
AAA_24
NACHT
G-alpha
Ploopntkinase3
AAA_5
Zeta_toxin
DUF87
Dynamin_N
Roc
AAA_33
MMR_HSR1
AAA_18
PRK
NTPase_1
RNA_helicase
AAA_21
SMC_N
ABC_ATPase
SbcCD_C
FERM_N
ABC_membrane
DUF2585
RsgA_GTPase
AAA_29
ABC_tran
TsaE
AAA_16
DEAD
AAA_7
AAA_25
Sigma54_activat
AAA_15
DLIC
KAP_NTPase
DUF815
AAA_24
APS_kinase
AAA_22
Zeta_toxin
DUF87
NACHT
AAA_30
SMC_N
Ploopntkinase3
G-alpha
MMR_HSR1
PRK
AAA_18
Dynamin_N
Roc
RNA_helicase
NTPase_1
AAA_33
AAA_21
AAA_5
SMC_N
NTPase_1
ABC_ATPase
SbcCD_C
FERM_N

References:

MMR_HSR1
8180467 Structure and evolution of a member of a new subfamily of GTP-binding proteins mapping to the human MHC class I region. Mamm Genome 1994;5:100-105.

DUF815

AAA_5
7646486 A 200-amino acid ATPase module in search of a basic function. Bioessays 1995;17:639-650.
9927482 AAA+: A class of chaperone-like ATPases associated with the assembly, operation, and disassembly of protein complexes. Genome Res 1999;9:27-43.

SbcCD_C

Zeta_toxin
12571357 Crystal structure of the plasmid maintenance system epsilon/zeta: functional mechanism of toxin zeta and inactivation by epsilon 2 zeta 2 complex formation. Proc Natl Acad Sci U S A 2003;100:1661-1666.

TsaE

DEAD
10322435 Unwinding RNA in Saccharomyces cerevisiae: DEAD-box proteins and related families. Trends Biochem Sci 1999;24:192-198.
9862990 The DEAD box RNA helicase family in Arabidopsis thaliana. Nucleic Acids Res 1999;27:628-636.

PRK
9548738 The crystal structure of phosphoribulokinase from Rhodobacter sphaeroides reveals a fold similar to that of adenylate kinase. Biochemistry 1998;37:5074-5085.
17143579 Functional characterization of a gene encoding a dual domain for uridine kinase and uracil phosphoribosyltransferase in Arabidopsis thaliana. Plant Mol Biol. 2007;63:465-477.

FERM_N
9757824 The FERM domain: a unique module involved in the linkage of cytoplasmic proteins to the membrane. Trends Biochem Sci 1998;23:281-282.
10098398 The N-termini of FAK and JAKs contain divergent band 4.1 domains. Trends Biochem Sci 1999;24:54-57.

RNA_helicase
2546125 Two related superfamilies of putative helicases involved in replication, recombination, repair and expression of DNA and RNA genomes. Nucleic Acids Res 1989;17:4713-4730.

G-alpha
8073283 Structures of active conformations of Gi alpha 1 and the mechanism of GTP hydrolysis. Science 1994;265:1405-1412.
8851656 How G proteins work: a continuing story. Trends Biochem Sci 1996;21:41-44.

NTPase_1

AAA_24

AAA_30

KAP_NTPase
15128444 A novel family of P-loop NTPases with an unusual phyletic distribution and transmembrane segments inserted within the NTPase domain. Genome Biol 2004;5:R30.

AAA_7

NACHT
10782090 The NACHT family - a new group of predicted NTPases implicated in apoptosis and MHC transcription activation. Trends Biochem Sci 2000;25:223-224.

AAA_33

Ploopntkinase3

Dynamin_N
8939066 Dynamin GTPase, a force-generating molecular switch. Bioessays 1996;18:885-893.
2144893 Molecular cloning of the microtubule-associated mechanochemical enzyme dynamin reveals homology with a new family of GTP-binding proteins. Nature 1990;347:256-261.

AAA_29

Sigma54_activat
11544185 Binding of transcriptional activators to sigma 54 in the presence of the transition state analog ADP-aluminum fluoride: insights into activator mechanochemical action. Genes Dev 2001;15:2282-2294.
12618438 Domain Architectures of sigma(54)-Dependent Transcriptional Activators. J Bacteriol 2003;185:1757-1767.

AAA_25

Roc

AAA_22

AAA_21

AAA_18

AAA_16

AAA_15

APS_kinase
9786849 Adenosine 5'-phosphosulfate kinase from Penicillium chrysogenum. site- directed mutagenesis at putative phosphoryl-accepting and ATP P-loop residues. J Biol Chem 1998;273:28583-28589.

ABC_tran
1864505 Homology between proteins controlling Streptomyces fradiae tylosin resistance and ATP-binding transport. Gene 1991;102:27-32.
1977073 Structure and function of haemolysin B,P-glycoprotein and other members of a novel family of membrane translocators. Mol Microbiol 1990;4:873-880.
2229036 Binding protein-dependent transport systems. J Bioenerg Biomembr 1990;22:571-592.
9872322 Crystal structure of the ATP-binding subunit of an ABC transporter. Nature 1998;396:703-707.

DUF2585

ABC_membrane

ABC_ATPase

RsgA_GTPase

SMC_N
10429180 Structural maintenance of chromosomes (SMC) proteins: conserved molecular properties for multiple biological functions. Eur J Biochem 1999;263:6-13.
9640531 SMC protein complexes and higher-order chromosome dynamics. Curr Opin Cell Biol 1998;10:317-322.

DUF87

DLIC
10545494 Direct interaction of pericentrin with cytoplasmic dynein light intermediate chain contributes to mitotic spindle organization. J Cell Biol 1999;147:481-492.
10893222 Light intermediate chain 1 defines a functional subfraction of cytoplasmic dynein which binds to pericentrin. J Biol Chem 2000;275:32763-32768.
11907264 Identification of a novel light intermediate chain (D2LIC) for mammalian cytoplasmic dynein 2. Mol Biol Cell 2002;13:817-829.

Domain	Description	Evalue	Bits	GA	Start	End
Dynamin_N	Dynamin family	0.4	2	21.00	19	63
AAA_15	AAA ATPase domain	0.33	2	32.10	25	55
ABC_membrane	ABC transporter transmembrane region	0	196	22.00	80	354
AAA_29	P-loop containing region of AAA domain	5.2E-06	18	27.00	420	448
AAA_15	AAA ATPase domain	0.00019	12	32.10	421	472
ABC_tran	ABC transporter	1.2E-37	121	23.10	423	570
AAA_7	P-loop containing dynein motor region	0.0074	7	25.80	425	451
Sigma54_activat	Sigma-54 interaction domain	0.013	7	20.20	427	456
TsaE	Threonylcarbamoyl adenosine biosynthesis protein TsaE	0.057	5	26.60	427	452
DLIC	Dynein light intermediate chain (DLIC)	0.21	2	19.30	428	460
AAA_25	AAA domain	0.0043	8	27.00	428	448
AAA_16	AAA ATPase domain	1.6E-06	20	32.60	428	586
DEAD	DEAD/DEAH box helicase	0.00051	11	20.60	428	587
AAA_30	AAA domain	0.00017	13	27.00	429	585
KAP_NTPase	KAP family P-loop domain	0.0051	7	20.00	429	602
RsgA_GTPase	RsgA GTPase	0.00013	13	30.00	430	462
APS_kinase	Adenylylsulphate kinase	0.0039	8	20.70	431	468
AAA_22	AAA domain	2.4E-05	16	27.00	432	592
DUF815	Protein of unknown function (DUF815)	0.011	6	20.10	432	475
AAA_24	AAA domain	0.0094	7	27.00	433	453
NACHT	NACHT domain	0.016	6	20.40	433	449
G-alpha	G-protein alpha subunit	5.9E-05	14	20.10	433	464
Ploopntkinase3	P-loop Nucleotide Kinase3	0.0064	8	27.00	434	457
AAA_5	AAA domain (dynein-related subfamily)	0.0016	10	20.80	434	476
Zeta_toxin	Zeta toxin	8.2E-06	17	20.10	434	472
DUF87	Domain of unknown function DUF87	0.0022	9	20.90	434	453
Dynamin_N	Dynamin family	0.081	4	21.00	434	448
Roc	Ras of Complex, Roc, domain of DAPkinase	0.053	5	27.00	434	456
AAA_33	AAA domain	0.021	6	27.00	434	449
MMR_HSR1	GTPase of unknown function	0.022	6	24.50	434	450
AAA_18	AAA domain	0.019	7	29.40	434	453
PRK	Phosphoribulokinase / Uridine kinase family	0.0099	7	20.60	434	456
NTPase_1	NTPase	0.0068	8	23.90	434	475
RNA_helicase	RNA helicase	0.11	4	21.50	435	450
AAA_21	AAA domain, putative AbiEii toxin, Type IV TA system	0.0039	8	27.00	435	465
SMC_N	RecF/RecN/SMC N terminal domain	2E-06	19	40.00	448	613
ABC_ATPase	Predicted ATPase of the ABC class	3.7E-06	17	19.30	515	571
SbcCD_C	Putative exonuclease SbcCD, C subunit	0.0015	10	27.00	558	584
FERM_N	FERM N-terminal domain	0.2	3	21.10	562	588
ABC_membrane	ABC transporter transmembrane region	0	200	22.00	730	1002
DUF2585	Protein of unknown function (DUF2585)	0.00059	11	25.00	792	881
RsgA_GTPase	RsgA GTPase	6.6E-05	14	30.00	1069	1102
AAA_29	P-loop containing region of AAA domain	9.5E-06	17	27.00	1070	1097
ABC_tran	ABC transporter	4.1E-37	119	23.10	1071	1220
TsaE	Threonylcarbamoyl adenosine biosynthesis protein TsaE	0.026	6	26.60	1071	1100
AAA_16	AAA ATPase domain	1.9E-05	16	32.60	1076	1109
DEAD	DEAD/DEAH box helicase	0.00037	12	20.60	1076	1237
AAA_7	P-loop containing dynein motor region	0.0031	8	25.80	1076	1105
AAA_25	AAA domain	0.0069	7	27.00	1077	1098
Sigma54_activat	Sigma-54 interaction domain	0.056	4	20.20	1077	1102
AAA_15	AAA ATPase domain	0.00051	11	32.10	1077	1107
DLIC	Dynein light intermediate chain (DLIC)	0.0019	8	19.30	1078	1109
KAP_NTPase	KAP family P-loop domain	0.019	5	20.00	1079	1221
DUF815	Protein of unknown function (DUF815)	0.0011	10	20.10	1080	1137
AAA_24	AAA domain	0.0008	10	27.00	1080	1121
APS_kinase	Adenylylsulphate kinase	0.0022	9	20.70	1080	1120
AAA_22	AAA domain	3.2E-06	19	27.00	1081	1236
Zeta_toxin	Zeta toxin	0.00031	11	20.10	1081	1120
DUF87	Domain of unknown function DUF87	0.0035	9	20.90	1081	1104
NACHT	NACHT domain	0.016	7	20.40	1082	1098
AAA_30	AAA domain	0.0017	9	27.00	1082	1233
SMC_N	RecF/RecN/SMC N terminal domain	0.055	4	40.00	1082	1098
Ploopntkinase3	P-loop Nucleotide Kinase3	0.0014	10	27.00	1082	1107
G-alpha	G-protein alpha subunit	0.00045	11	20.10	1082	1107
MMR_HSR1	GTPase of unknown function	0.01	7	24.50	1083	1100
PRK	Phosphoribulokinase / Uridine kinase family	0.0065	8	20.60	1083	1103
AAA_18	AAA domain	0.011	8	29.40	1083	1102
Dynamin_N	Dynamin family	0.022	6	21.00	1083	1101
Roc	Ras of Complex, Roc, domain of DAPkinase	0.02	7	27.00	1083	1106
RNA_helicase	RNA helicase	0.054	5	21.50	1083	1101
NTPase_1	NTPase	0.15	3	23.90	1083	1100
AAA_33	AAA domain	0.041	5	27.00	1084	1098
AAA_21	AAA domain, putative AbiEii toxin, Type IV TA system	0.0013	10	27.00	1084	1125
AAA_5	AAA domain (dynein-related subfamily)	0.0072	8	20.80	1084	1106
SMC_N	RecF/RecN/SMC N terminal domain	1.4E-06	19	40.00	1112	1263
NTPase_1	NTPase	0.68	1	23.90	1170	1255
ABC_ATPase	Predicted ATPase of the ABC class	0.0033	8	19.30	1171	1222
SbcCD_C	Putative exonuclease SbcCD, C subunit	0.0075	8	27.00	1208	1234
FERM_N	FERM N-terminal domain	0.12	4	21.10	1212	1238