c2pfam

AT4G02150.1 :

Domain Description Evalue Bits GA Start End
IBB Importin beta binding domain 2E-27 86 23.60 12 96
HEAT_EZ HEAT-like repeat 0.3 2 27.00 49 92
CTNNBL Catenin-beta-like, Arm-motif containing nuclear 0.62 0 20.90 91 129
Arm Armadillo/beta-catenin-like repeat 2.9E-13 40 20.60 108 148
Atx10homo_assoc Spinocerebellar ataxia type 10 protein domain 0.16 2 22.40 112 157
DUF3361 Domain of unknown function (DUF3361) 0.73 0 27.20 116 182
RICTOR_V Rapamycin-insensitive companion of mTOR, domain 5 0.27 2 27.00 118 151
HEAT HEAT repeat 0.0016 9 23.50 119 149
Arm_2 Armadillo-like 5.7E-05 13 20.40 120 189
HEAT_2 HEAT repeats 5.7E-11 33 27.70 121 190
V-ATPase_H_C V-ATPase subunit H 0.037 4 20.80 122 187
Adaptin_N Adaptin N terminal region 5.8E-08 22 20.30 130 403
HEAT_EZ HEAT-like repeat 4.4E-10 30 27.00 133 187
HEAT_PBS PBS lyase HEAT-like repeat 0.33 2 20.90 136 148
RICTOR_V Rapamycin-insensitive companion of mTOR, domain 5 0.0044 7 27.00 140 190
CTNNBL Catenin-beta-like, Arm-motif containing nuclear 0.13 3 20.90 150 182
Arm Armadillo/beta-catenin-like repeat 8.1E-16 48 20.60 150 189
NopRA1 Nucleolar pre-ribosomal-associated protein 1 0.019 5 29.60 160 186
HEAT HEAT repeat 1.9E-07 21 23.50 163 189
HEAT_PBS PBS lyase HEAT-like repeat 0.0049 8 20.90 177 190
Atx10homo_assoc Spinocerebellar ataxia type 10 protein domain 0.0028 8 22.40 178 234
RICTOR_V Rapamycin-insensitive companion of mTOR, domain 5 0.033 5 27.00 180 222
Arm Armadillo/beta-catenin-like repeat 6.7E-11 32 20.60 192 233
HEAT_EZ HEAT-like repeat 1E-06 19 27.00 222 272
HEAT_PBS PBS lyase HEAT-like repeat 0.51 2 20.90 222 254
HEAT_2 HEAT repeats 0.0015 9 27.70 244 284
Arm Armadillo/beta-catenin-like repeat 4.8E-10 29 20.60 246 274
HEAT HEAT repeat 0.14 3 23.50 247 273
Arm_2 Armadillo-like 0.36 0 20.40 247 282
Adaptin_N Adaptin N terminal region 2.1E-05 13 20.30 247 501
NopRA1 Nucleolar pre-ribosomal-associated protein 1 0.53 0 29.60 247 275
V-ATPase_H_C V-ATPase subunit H 0.00052 10 20.80 249 315
DUF3361 Domain of unknown function (DUF3361) 0.083 3 27.20 255 308
CTNNBL Catenin-beta-like, Arm-motif containing nuclear 0.0057 7 20.90 261 304
Arm Armadillo/beta-catenin-like repeat 1.4E-13 41 20.60 276 315
HEAT_EZ HEAT-like repeat 0.00077 10 27.00 285 314
HEAT HEAT repeat 0.00057 10 23.50 288 316
HEAT_2 HEAT repeats 5.6E-08 23 27.70 290 395
HEAT_EZ HEAT-like repeat 7.6E-07 20 27.00 307 357
Atx10homo_assoc Spinocerebellar ataxia type 10 protein domain 0.003 8 22.40 308 369
Arm Armadillo/beta-catenin-like repeat 1.8E-12 37 20.60 319 359
Arm_2 Armadillo-like 1.1E-05 15 20.40 322 418
NopRA1 Nucleolar pre-ribosomal-associated protein 1 0.25 1 29.60 326 360
V-ATPase_H_C V-ATPase subunit H 0.18 2 20.80 329 392
HEAT HEAT repeat 0.063 4 23.50 331 358
DUF3361 Domain of unknown function (DUF3361) 0.047 4 27.20 339 392
RICTOR_V Rapamycin-insensitive companion of mTOR, domain 5 0.55 1 27.00 347 383
Arm Armadillo/beta-catenin-like repeat 5E-13 39 20.60 361 400
HEAT_2 HEAT repeats 0.11 3 27.70 376 439
HEAT_EZ HEAT-like repeat 0.27 2 27.00 388 424
Arm Armadillo/beta-catenin-like repeat 3.9E-11 33 20.60 405 442
HEAT HEAT repeat 0.86 1 23.50 420 442
DUF3361 Domain of unknown function (DUF3361) 0.024 5 27.20 421 503
Arm_2 Armadillo-like 0.0033 7 20.40 424 496
Arm_3 Atypical Arm repeat 3.1E-24 74 28.80 459 513
CTNNBL Catenin-beta-like, Arm-motif containing nuclear 0.011 6 20.90 459 489
V-ATPase_H_C V-ATPase subunit H 0.16 2 20.80 462 495

531

IBB
HEAT_EZ
CTNNBL
Arm
Atx10homo_assoc
DUF3361
RICTOR_V
HEAT
Arm_2
HEAT_2
V-ATPase_H_C
Adaptin_N
HEAT_EZ
HEAT_PBS
RICTOR_V
CTNNBL
Arm
NopRA1
HEAT
HEAT_PBS
Atx10homo_assoc
RICTOR_V
Arm
HEAT_EZ
HEAT_PBS
HEAT_2
Arm
HEAT
Arm_2
Adaptin_N
NopRA1
V-ATPase_H_C
DUF3361
CTNNBL
Arm
HEAT_EZ
HEAT
HEAT_2
HEAT_EZ
Atx10homo_assoc
Arm
Arm_2
NopRA1
V-ATPase_H_C
HEAT
DUF3361
RICTOR_V
Arm
HEAT_2
HEAT_EZ
Arm
HEAT
DUF3361
Arm_2
Arm_3
CTNNBL
V-ATPase_H_C

References:

RICTOR_V

V-ATPase_H_C
10954728 Regulation of yeast ectoapyrase ynd1p activity by activator subunit Vma13p of vacuolar H+-ATPase. J Biol Chem 2000;275:35592-35599.
18708638 Functional characterization of the N-terminal domain of subunit H (Vma13p) of the yeast vacuolar ATPase. J Biol Chem. 2008; [Epub ahead of print]
16141210 Structural and functional separation of the N- and C-terminal domains of the yeast V-ATPase subunit H. J Biol Chem. 2005;280:36978-36985.

DUF3361

Arm
9298899 Three-dimensional structure of the armadillo repeat region of beta-catenin. Cell 1997;90:871-882.
8573337 Signal transduction of beta-catenin. Curr Opin Cell Biol 1995;7:634-640.
9309175 Armadillo and dTCF: a marriage made in the nucleus. Curr Opin Genet Dev 1997;7:459-466.
8259519 Association of the APC tumor suppressor protein with catenins. Science 1993;262:1734-1737.
8259518 Association of the APC gene product with beta-catenin. Science 1993;262:1731-1734.
2261639 The segment polarity gene armadillo encodes a functionally modular protein that is the Drosophila homolog of human plakoglobin. Cell 1990;63:1167-1176.

Adaptin_N
9261055 Linking cargo to vesicle formation: receptor tail interactions with coat proteins. Curr Opin Cell Biol 1997;9:488-495.
2495531 Structural and functional division into two domains of the large (100- to 115-kDa)chains of the clathrin-associated protein complex AP-2. Proc Natl Acad Sci U S A 1989;86:2612-2616.

IBB
9695948 Crystallographic analysis of the recognition of a nuclear localization signal by the nuclear import factor karyopherin alpha. Cell 1998;94:193-204.
9612083 Importins and exportins: how to get in and out of the nucleus [published erratum appears in Trends Biochem Sci 1998 Jul;23(7):235] Trends Biochem Sci 1998;23:185-189.
9582265 Transport into and out of the cell nucleus. EMBO J 1998;17:2721-2727.
8692858 The binding site of karyopherin alpha for karyopherin beta overlaps with a nuclear localization sequence. Proc Natl Acad Sci U S A 1996;93:6572-6576.
8617226 A 41 amino acid motif in importin-alpha confers binding to importin- beta and hence transit into the nucleus. EMBO J 1996;15:1810-1817.

Atx10homo_assoc
15201271 Ataxin-10, the spinocerebellar ataxia type 10 neurodegenerative disorder protein, is essential for survival of cerebellar neurons. J Biol Chem. 2004;279:35542-35550.

HEAT_PBS
8132596 Oligomeric structure, enzyme kinetics, and substrate specificity of the phycocyanin alpha subunit phycocyanobilin lyase. J Biol Chem 1994;269:8686-8694.
9023176 A role for cpeYZ in cyanobacterial phycoerythrin biosynthesis. J Bacteriol 1997;179:998-1006.
10708746 Novel activity of a phycobiliprotein lyase: both the attachment of phycocyanobilin and the isomerization to phycoviolobilin are catalyzed by the proteins PecE and PecF encoded by the phycoerythrocyanin operon. FEBS Lett 2000;469:9-13.
9882677 A polypeptide with similarity to phycocyanin alpha-subunit phycocyanobilin lyase involved in degradation of phycobilisomes. J Bacteriol 1999;181:610-617.

HEAT
7550332 HEAT repeats in the Huntington's disease protein. Nat Genet 1995;11:115-116.
9989501 The structure of the protein phosphatase 2A PR65/A subunit reveals the conformation of its 15 tandemly repeated HEAT motifs. Cell 1999;96:99-110.

CTNNBL

HEAT_EZ

HEAT_2

NopRA1

Arm_2

Arm_3

Domain	Description	Evalue	Bits	GA	Start	End
IBB	Importin beta binding domain	2E-27	86	23.60	12	96
HEAT_EZ	HEAT-like repeat	0.3	2	27.00	49	92
CTNNBL	Catenin-beta-like, Arm-motif containing nuclear	0.62	0	20.90	91	129
Arm	Armadillo/beta-catenin-like repeat	2.9E-13	40	20.60	108	148
Atx10homo_assoc	Spinocerebellar ataxia type 10 protein domain	0.16	2	22.40	112	157
DUF3361	Domain of unknown function (DUF3361)	0.73	0	27.20	116	182
RICTOR_V	Rapamycin-insensitive companion of mTOR, domain 5	0.27	2	27.00	118	151
HEAT	HEAT repeat	0.0016	9	23.50	119	149
Arm_2	Armadillo-like	5.7E-05	13	20.40	120	189
HEAT_2	HEAT repeats	5.7E-11	33	27.70	121	190
V-ATPase_H_C	V-ATPase subunit H	0.037	4	20.80	122	187
Adaptin_N	Adaptin N terminal region	5.8E-08	22	20.30	130	403
HEAT_EZ	HEAT-like repeat	4.4E-10	30	27.00	133	187
HEAT_PBS	PBS lyase HEAT-like repeat	0.33	2	20.90	136	148
RICTOR_V	Rapamycin-insensitive companion of mTOR, domain 5	0.0044	7	27.00	140	190
CTNNBL	Catenin-beta-like, Arm-motif containing nuclear	0.13	3	20.90	150	182
Arm	Armadillo/beta-catenin-like repeat	8.1E-16	48	20.60	150	189
NopRA1	Nucleolar pre-ribosomal-associated protein 1	0.019	5	29.60	160	186
HEAT	HEAT repeat	1.9E-07	21	23.50	163	189
HEAT_PBS	PBS lyase HEAT-like repeat	0.0049	8	20.90	177	190
Atx10homo_assoc	Spinocerebellar ataxia type 10 protein domain	0.0028	8	22.40	178	234
RICTOR_V	Rapamycin-insensitive companion of mTOR, domain 5	0.033	5	27.00	180	222
Arm	Armadillo/beta-catenin-like repeat	6.7E-11	32	20.60	192	233
HEAT_EZ	HEAT-like repeat	1E-06	19	27.00	222	272
HEAT_PBS	PBS lyase HEAT-like repeat	0.51	2	20.90	222	254
HEAT_2	HEAT repeats	0.0015	9	27.70	244	284
Arm	Armadillo/beta-catenin-like repeat	4.8E-10	29	20.60	246	274
HEAT	HEAT repeat	0.14	3	23.50	247	273
Arm_2	Armadillo-like	0.36	0	20.40	247	282
Adaptin_N	Adaptin N terminal region	2.1E-05	13	20.30	247	501
NopRA1	Nucleolar pre-ribosomal-associated protein 1	0.53	0	29.60	247	275
V-ATPase_H_C	V-ATPase subunit H	0.00052	10	20.80	249	315
DUF3361	Domain of unknown function (DUF3361)	0.083	3	27.20	255	308
CTNNBL	Catenin-beta-like, Arm-motif containing nuclear	0.0057	7	20.90	261	304
Arm	Armadillo/beta-catenin-like repeat	1.4E-13	41	20.60	276	315
HEAT_EZ	HEAT-like repeat	0.00077	10	27.00	285	314
HEAT	HEAT repeat	0.00057	10	23.50	288	316
HEAT_2	HEAT repeats	5.6E-08	23	27.70	290	395
HEAT_EZ	HEAT-like repeat	7.6E-07	20	27.00	307	357
Atx10homo_assoc	Spinocerebellar ataxia type 10 protein domain	0.003	8	22.40	308	369
Arm	Armadillo/beta-catenin-like repeat	1.8E-12	37	20.60	319	359
Arm_2	Armadillo-like	1.1E-05	15	20.40	322	418
NopRA1	Nucleolar pre-ribosomal-associated protein 1	0.25	1	29.60	326	360
V-ATPase_H_C	V-ATPase subunit H	0.18	2	20.80	329	392
HEAT	HEAT repeat	0.063	4	23.50	331	358
DUF3361	Domain of unknown function (DUF3361)	0.047	4	27.20	339	392
RICTOR_V	Rapamycin-insensitive companion of mTOR, domain 5	0.55	1	27.00	347	383
Arm	Armadillo/beta-catenin-like repeat	5E-13	39	20.60	361	400
HEAT_2	HEAT repeats	0.11	3	27.70	376	439
HEAT_EZ	HEAT-like repeat	0.27	2	27.00	388	424
Arm	Armadillo/beta-catenin-like repeat	3.9E-11	33	20.60	405	442
HEAT	HEAT repeat	0.86	1	23.50	420	442
DUF3361	Domain of unknown function (DUF3361)	0.024	5	27.20	421	503
Arm_2	Armadillo-like	0.0033	7	20.40	424	496
Arm_3	Atypical Arm repeat	3.1E-24	74	28.80	459	513
CTNNBL	Catenin-beta-like, Arm-motif containing nuclear	0.011	6	20.90	459	489
V-ATPase_H_C	V-ATPase subunit H	0.16	2	20.80	462	495