c2pfam

AT4G04740.1 :

Domain Description Evalue Bits GA Start End
Pkinase Protein kinase domain 0 243 20.40 69 327
PK_Tyr_Ser-Thr Protein tyrosine and serine/threonine kinase 2.4E-27 86 23.10 71 323
APH Phosphotransferase enzyme family 0.45 0 22.40 100 155
Kdo Lipopolysaccharide kinase (Kdo/WaaP) family 8.7E-07 19 20.90 144 215
Kinase-like Kinase-like 1.1E-05 15 25.00 177 315
APH Phosphotransferase enzyme family 0.0014 9 22.40 188 217
CCM2_C Cerebral cavernous malformation protein, harmonin-homology 0.099 3 27.30 262 283
EF-hand_7 EF-hand domain pair 1.8E-06 19 30.00 361 396
SPARC_Ca_bdg Secreted protein acidic and rich in cysteine Ca binding region 0.0025 8 21.40 364 431
EF-hand_4 Cytoskeletal-regulatory complex EF hand 1.2E-06 19 21.30 366 433
EF-hand_8 EF-hand domain pair 0.0095 6 28.00 366 392
EF-hand_7 EF-hand domain pair 7.7E-13 39 30.00 374 434
EF-hand_1 EF hand 3.9E-07 20 25.40 374 400
EF-hand_6 EF-hand domain 1.3E-06 18 25.00 374 400
EF-hand_5 EF hand 5.4E-05 13 25.90 374 395
EF-hand_9 EF-hand domain 0.00068 10 37.00 376 436
EF-hand_11 EF-hand domain 0.0021 9 21.70 377 433
EF-hand_8 EF-hand domain pair 7.7E-09 25 28.00 386 434
CCM2_C Cerebral cavernous malformation protein, harmonin-homology 0.0027 8 27.30 387 413
EF-hand_1 EF hand 3.3E-06 17 25.40 410 433
EFhand_Ca_insen Ca2+ insensitive EF hand 0.34 1 20.80 411 435
PK_Tyr_Ser-Thr Protein tyrosine and serine/threonine kinase 0.85 -1 23.10 414 472
EF-hand_6 EF-hand domain 0.00017 12 25.00 416 433
EF-hand_5 EF hand 0.014 5 25.90 418 430
EF-hand_11 EF-hand domain 0.038 5 21.70 433 505
SPARC_Ca_bdg Secreted protein acidic and rich in cysteine Ca binding region 1.1E-07 22 21.40 442 501
EF-hand_7 EF-hand domain pair 4.2E-18 56 30.00 444 506
EFhand_Ca_insen Ca2+ insensitive EF hand 0.0019 9 20.80 444 469
EF-hand_1 EF hand 4.6E-10 29 25.40 446 472
EF-hand_8 EF-hand domain pair 0.0023 8 28.00 446 471
EF-hand_4 Cytoskeletal-regulatory complex EF hand 7.5E-07 19 21.30 447 506
EF-hand_6 EF-hand domain 1.5E-09 27 25.00 447 473
EF-hand_5 EF hand 9.7E-07 18 25.90 448 468
EF-hand_9 EF-hand domain 9E-05 13 37.00 449 506
EF-hand_8 EF-hand domain pair 8.2E-12 35 28.00 458 505
EF-hand_5 EF hand 1.2E-08 24 25.90 481 505
EF-hand_1 EF hand 3.3E-12 36 25.40 481 506
EF-hand_6 EF-hand domain 7.8E-07 19 25.00 482 506

520

Pkinase
PK_Tyr_Ser-Thr
APH
Kdo
Kinase-like
APH
CCM2_C
EF-hand_7
SPARC_Ca_bdg
EF-hand_4
EF-hand_8
EF-hand_7
EF-hand_1
EF-hand_6
EF-hand_5
EF-hand_9
EF-hand_11
EF-hand_8
CCM2_C
EF-hand_1
EFhand_Ca_insen
PK_Tyr_Ser-Thr
EF-hand_6
EF-hand_5
EF-hand_11
SPARC_Ca_bdg
EF-hand_7
EFhand_Ca_insen
EF-hand_1
EF-hand_8
EF-hand_4
EF-hand_6
EF-hand_5
EF-hand_9
EF-hand_8
EF-hand_5
EF-hand_1
EF-hand_6

References:

APH
2163618 Cloning of aminoglycoside phosphotransferase (APH) gene from antibiotic- producing strain of Bacillus circulans into a high-expression vector, pKK223-3. Purification, properties and location of the enzyme [published erratum appears in Biochem J 1991 Feb 1 Biochem J 1990;268:671-677.
2167474 PCR cloning of a streptomycin phosphotransferase (aphE) gene from Streptomyces griseus ATCC 12475. Nucleic Acids Res 1990;18:4615-4615.

EF-hand_9

SPARC_Ca_bdg
16121393 The C-terminal Ca2+-binding domain of SPARC confers anti-spreading activity to human urothelial cells. J Cell Physiol. 2006;206:211-220.

EF-hand_7

EF-hand_6

Kdo
11069912 Purification and characterization of WaaP from Escherichia coli, a lipopolysaccharide kinase essential for outer membrane stability. J Biol Chem 2001;276:5498-5504.
12021457 Lipopolysaccharide phosphorylating enzymes encoded in the genomes of Gram-negative bacteria are related to the eukaryotic protein kinases. Protein Sci 2002;11:1580-1584.
10531340 A Haemophilus influenzae gene that encodes a membrane bound 3-deoxy-D-manno-octulosonic acid (Kdo) kinase. Possible involvement of kdo phosphorylation in bacterial virulence. J Biol Chem 1999;274:31391-31400.

EF-hand_4

Kinase-like

EF-hand_1

EF-hand_8

CCM2_C

Pkinase
1956325 Protein kinase catalytic domain sequence database: identification of conserved features of primary structure and classification of family members. Methods Enzymol 1991;200:38-62.
7768349 Protein kinases 6. The eukaryotic protein kinase superfamily: kinase (catalytic) domain structure and classification. FASEB J 1995;9:576-596.
9020587 The protein kinases of budding yeast: six score and more. Trends Biochem Sci 1997;22:18-22.

EFhand_Ca_insen
11573089 Ca2+-independent binding of an EF-hand domain to a novel motif in the alpha-actinin-titin complex. Nat Struct Biol. 2001;8:853-857.

EF-hand_11

PK_Tyr_Ser-Thr

EF-hand_5

Domain	Description	Evalue	Bits	GA	Start	End
Pkinase	Protein kinase domain	0	243	20.40	69	327
PK_Tyr_Ser-Thr	Protein tyrosine and serine/threonine kinase	2.4E-27	86	23.10	71	323
APH	Phosphotransferase enzyme family	0.45	0	22.40	100	155
Kdo	Lipopolysaccharide kinase (Kdo/WaaP) family	8.7E-07	19	20.90	144	215
Kinase-like	Kinase-like	1.1E-05	15	25.00	177	315
APH	Phosphotransferase enzyme family	0.0014	9	22.40	188	217
CCM2_C	Cerebral cavernous malformation protein, harmonin-homology	0.099	3	27.30	262	283
EF-hand_7	EF-hand domain pair	1.8E-06	19	30.00	361	396
SPARC_Ca_bdg	Secreted protein acidic and rich in cysteine Ca binding region	0.0025	8	21.40	364	431
EF-hand_4	Cytoskeletal-regulatory complex EF hand	1.2E-06	19	21.30	366	433
EF-hand_8	EF-hand domain pair	0.0095	6	28.00	366	392
EF-hand_7	EF-hand domain pair	7.7E-13	39	30.00	374	434
EF-hand_1	EF hand	3.9E-07	20	25.40	374	400
EF-hand_6	EF-hand domain	1.3E-06	18	25.00	374	400
EF-hand_5	EF hand	5.4E-05	13	25.90	374	395
EF-hand_9	EF-hand domain	0.00068	10	37.00	376	436
EF-hand_11	EF-hand domain	0.0021	9	21.70	377	433
EF-hand_8	EF-hand domain pair	7.7E-09	25	28.00	386	434
CCM2_C	Cerebral cavernous malformation protein, harmonin-homology	0.0027	8	27.30	387	413
EF-hand_1	EF hand	3.3E-06	17	25.40	410	433
EFhand_Ca_insen	Ca2+ insensitive EF hand	0.34	1	20.80	411	435
PK_Tyr_Ser-Thr	Protein tyrosine and serine/threonine kinase	0.85	-1	23.10	414	472
EF-hand_6	EF-hand domain	0.00017	12	25.00	416	433
EF-hand_5	EF hand	0.014	5	25.90	418	430
EF-hand_11	EF-hand domain	0.038	5	21.70	433	505
SPARC_Ca_bdg	Secreted protein acidic and rich in cysteine Ca binding region	1.1E-07	22	21.40	442	501
EF-hand_7	EF-hand domain pair	4.2E-18	56	30.00	444	506
EFhand_Ca_insen	Ca2+ insensitive EF hand	0.0019	9	20.80	444	469
EF-hand_1	EF hand	4.6E-10	29	25.40	446	472
EF-hand_8	EF-hand domain pair	0.0023	8	28.00	446	471
EF-hand_4	Cytoskeletal-regulatory complex EF hand	7.5E-07	19	21.30	447	506
EF-hand_6	EF-hand domain	1.5E-09	27	25.00	447	473
EF-hand_5	EF hand	9.7E-07	18	25.90	448	468
EF-hand_9	EF-hand domain	9E-05	13	37.00	449	506
EF-hand_8	EF-hand domain pair	8.2E-12	35	28.00	458	505
EF-hand_5	EF hand	1.2E-08	24	25.90	481	505
EF-hand_1	EF hand	3.3E-12	36	25.40	481	506
EF-hand_6	EF-hand domain	7.8E-07	19	25.00	482	506