c2pfam

AT4G08850.1 :

Domain Description Evalue Bits GA Start End
LRRNT_2 Leucine rich repeat N-terminal domain 1.6E-12 38 20.70 50 91
LRR_4 Leucine Rich repeats (2 copies) 7.2E-05 13 27.00 96 137
LRR_8 Leucine rich repeat 9.6E-05 12 27.00 97 154
LRR_6 Leucine Rich repeat 0.13 3 23.40 117 132
LRR_8 Leucine rich repeat 2.7E-06 17 27.00 118 178
LRR_4 Leucine Rich repeats (2 copies) 5.5E-06 17 27.00 143 182
LRR_8 Leucine rich repeat 7.1E-07 19 27.00 166 226
LRR_4 Leucine Rich repeats (2 copies) 0.015 6 27.00 191 228
MitoNEET_N Iron-containing outer mitochondrial membrane protein N-terminus 0.1 3 21.30 204 216
LRR_4 Leucine Rich repeats (2 copies) 1.2E-05 16 27.00 214 254
LRR_8 Leucine rich repeat 5.6E-07 20 27.00 235 274
LRR_9 Leucine-rich repeat 0.12 2 30.50 235 275
LRR_8 Leucine rich repeat 9.1E-09 25 27.00 238 298
LRR_4 Leucine Rich repeats (2 copies) 8.9E-07 20 27.00 238 274
LRR_1 Leucine Rich Repeat 6.5E-05 14 20.60 239 261
LRR_4 Leucine Rich repeats (2 copies) 2.1E-05 15 27.00 262 302
LRR_8 Leucine rich repeat 0.00072 10 27.00 287 324
LRR_8 Leucine rich repeat 2.7E-09 27 27.00 311 370
LRR_4 Leucine Rich repeats (2 copies) 0.011 7 27.00 312 347
LRR_1 Leucine Rich Repeat 0.57 2 20.60 339 357
MitoNEET_N Iron-containing outer mitochondrial membrane protein N-terminus 0.063 4 21.30 349 363
LRR_4 Leucine Rich repeats (2 copies) 0.00082 10 27.00 359 395
LRR_1 Leucine Rich Repeat 0.71 1 20.60 360 378
LRR_8 Leucine rich repeat 5.9E-05 13 27.00 381 418
LRR_8 Leucine rich repeat 6.4E-06 16 27.00 407 466
LRR_4 Leucine Rich repeats (2 copies) 1 0 27.00 407 447
LRR_1 Leucine Rich Repeat 0.52 2 20.60 407 427
LRR_6 Leucine Rich repeat 0.92 0 23.40 454 467
LRR_8 Leucine rich repeat 1.8E-08 24 27.00 454 514
LRR_4 Leucine Rich repeats (2 copies) 0.98 0 27.00 455 465
LRR_1 Leucine Rich Repeat 0.39 2 20.60 456 473
LRR_4 Leucine Rich repeats (2 copies) 3.5E-07 21 27.00 479 515
LRR_8 Leucine rich repeat 3.6E-09 27 27.00 480 538
LRR_6 Leucine Rich repeat 0.0068 7 23.40 502 517
LRR_9 Leucine-rich repeat 0.00051 10 30.50 502 604
LRR_1 Leucine Rich Repeat 0.0094 7 20.60 504 524
LRR_4 Leucine Rich repeats (2 copies) 5.6E-07 20 27.00 530 566
LRR_8 Leucine rich repeat 4.3E-13 39 27.00 550 610
LRR_6 Leucine Rich repeat 0.0023 8 23.40 550 565
LRR_1 Leucine Rich Repeat 0.00029 12 20.60 551 573
LRR_4 Leucine Rich repeats (2 copies) 9.1E-05 13 27.00 574 611
LRR_1 Leucine Rich Repeat 0.2 3 20.60 576 596
LRR_6 Leucine Rich repeat 0.021 5 23.40 599 613
LRR_1 Leucine Rich Repeat 0.0089 7 20.60 600 621
LRR_8 Leucine rich repeat 3.2E-10 30 27.00 616 658
LRR_6 Leucine Rich repeat 0.00044 11 23.40 621 636
LRR_4 Leucine Rich repeats (2 copies) 1.8E-08 25 27.00 622 662
LRR_1 Leucine Rich Repeat 9.3E-06 16 20.60 623 643
MitoNEET_N Iron-containing outer mitochondrial membrane protein N-terminus 0.96 0 21.30 638 653
LRR_1 Leucine Rich Repeat 0.039 5 20.60 648 664
LRR_6 Leucine Rich repeat 0.0096 6 23.40 648 660
TMEM154 TMEM154 protein family 1.5E-06 18 30.30 687 745
Insulin_TMD Insulin receptor trans-membrane segment 9.6E-08 22 33.40 705 737
EphA2_TM Ephrin type-A receptor 2 transmembrane domain 0.00043 11 28.90 715 748
Pkinase Protein kinase domain 0 160 20.40 779 1040
PK_Tyr_Ser-Thr Protein tyrosine and serine/threonine kinase 0 153 23.10 781 1042
APH Phosphotransferase enzyme family 0.14 2 22.40 813 873
Fructosamin_kin Fructosamine kinase 0.018 4 20.00 815 859
PIP49_C Pancreatitis induced protein 49 C terminal 0.00021 11 28.10 827 926
APH Phosphotransferase enzyme family 6.2E-05 13 22.40 840 928
Fructosamin_kin Fructosamine kinase 0.013 5 20.00 872 919
Pkinase_fungal Fungal protein kinase 1.6E-05 14 24.10 900 952

1045

LRRNT_2
LRR_4
LRR_8
LRR_6
LRR_8
LRR_4
LRR_8
LRR_4
MitoNEET_N
LRR_4
LRR_8
LRR_9
LRR_8
LRR_4
LRR_1
LRR_4
LRR_8
LRR_8
LRR_4
LRR_1
MitoNEET_N
LRR_4
LRR_1
LRR_8
LRR_8
LRR_4
LRR_1
LRR_6
LRR_8
LRR_4
LRR_1
LRR_4
LRR_8
LRR_6
LRR_9
LRR_1
LRR_4
LRR_8
LRR_6
LRR_1
LRR_4
LRR_1
LRR_6
LRR_1
LRR_8
LRR_6
LRR_4
LRR_1
MitoNEET_N
LRR_1
LRR_6
TMEM154
Insulin_TMD
EphA2_TM
Pkinase
PK_Tyr_Ser-Thr
APH
Fructosamin_kin
PIP49_C
APH
Fructosamin_kin
Pkinase_fungal

References:

APH
2163618 Cloning of aminoglycoside phosphotransferase (APH) gene from antibiotic- producing strain of Bacillus circulans into a high-expression vector, pKK223-3. Purification, properties and location of the enzyme [published erratum appears in Biochem J 1991 Feb 1 Biochem J 1990;268:671-677.
2167474 PCR cloning of a streptomycin phosphotransferase (aphE) gene from Streptomyces griseus ATCC 12475. Nucleic Acids Res 1990;18:4615-4615.

PIP49_C
11281735 Cloning and expression of the mouse PIP49 (Pancreatitis Induced Protein 49) mRNA which encodes a new putative transmembrane protein activated in the pancreas with acute pancreatitis. Mol Cell Biol Res Commun. 2000;4:188-193.

Pkinase_fungal

MitoNEET_N
17376863 MitoNEET is an iron-containing outer mitochondrial membrane protein that regulates oxidative capacity. Proc Natl Acad Sci U S A. 2007;104:5318-5323.
17584744 The outer mitochondrial membrane protein mitoNEET contains a novel redox-active 2Fe-2S cluster. J Biol Chem. 2007;282:23745-23749.
17766440 MitoNEET is a uniquely folded 2Fe 2S outer mitochondrial membrane protein stabilized by pioglitazone. Proc Natl Acad Sci U S A. 2007;104:14342-14347.

TMEM154

LRR_1
7817399 The leucine-rich repeat: a versatile binding motif. Trends Biochem Sci 1994;19:415-421.
8264799 Crystal structure of porcine ribonuclease inhibitor, a protein with leucine-rich repeats. Nature 1993;366:751-756.

LRRNT_2
7817399 The leucine-rich repeat: a versatile binding motif. Trends Biochem Sci 1994;19:415-421.

LRR_9

LRR_8

LRR_6

LRR_4

Pkinase
1956325 Protein kinase catalytic domain sequence database: identification of conserved features of primary structure and classification of family members. Methods Enzymol 1991;200:38-62.
7768349 Protein kinases 6. The eukaryotic protein kinase superfamily: kinase (catalytic) domain structure and classification. FASEB J 1995;9:576-596.
9020587 The protein kinases of budding yeast: six score and more. Trends Biochem Sci 1997;22:18-22.

Fructosamin_kin
11016445 Identification, cloning, and heterologous expression of a mammalian fructosamine-3-kinase. Diabetes 2000;49:1627-1634.

Insulin_TMD

EphA2_TM

PK_Tyr_Ser-Thr

Domain	Description	Evalue	Bits	GA	Start	End
LRRNT_2	Leucine rich repeat N-terminal domain	1.6E-12	38	20.70	50	91
LRR_4	Leucine Rich repeats (2 copies)	7.2E-05	13	27.00	96	137
LRR_8	Leucine rich repeat	9.6E-05	12	27.00	97	154
LRR_6	Leucine Rich repeat	0.13	3	23.40	117	132
LRR_8	Leucine rich repeat	2.7E-06	17	27.00	118	178
LRR_4	Leucine Rich repeats (2 copies)	5.5E-06	17	27.00	143	182
LRR_8	Leucine rich repeat	7.1E-07	19	27.00	166	226
LRR_4	Leucine Rich repeats (2 copies)	0.015	6	27.00	191	228
MitoNEET_N	Iron-containing outer mitochondrial membrane protein N-terminus	0.1	3	21.30	204	216
LRR_4	Leucine Rich repeats (2 copies)	1.2E-05	16	27.00	214	254
LRR_8	Leucine rich repeat	5.6E-07	20	27.00	235	274
LRR_9	Leucine-rich repeat	0.12	2	30.50	235	275
LRR_8	Leucine rich repeat	9.1E-09	25	27.00	238	298
LRR_4	Leucine Rich repeats (2 copies)	8.9E-07	20	27.00	238	274
LRR_1	Leucine Rich Repeat	6.5E-05	14	20.60	239	261
LRR_4	Leucine Rich repeats (2 copies)	2.1E-05	15	27.00	262	302
LRR_8	Leucine rich repeat	0.00072	10	27.00	287	324
LRR_8	Leucine rich repeat	2.7E-09	27	27.00	311	370
LRR_4	Leucine Rich repeats (2 copies)	0.011	7	27.00	312	347
LRR_1	Leucine Rich Repeat	0.57	2	20.60	339	357
MitoNEET_N	Iron-containing outer mitochondrial membrane protein N-terminus	0.063	4	21.30	349	363
LRR_4	Leucine Rich repeats (2 copies)	0.00082	10	27.00	359	395
LRR_1	Leucine Rich Repeat	0.71	1	20.60	360	378
LRR_8	Leucine rich repeat	5.9E-05	13	27.00	381	418
LRR_8	Leucine rich repeat	6.4E-06	16	27.00	407	466
LRR_4	Leucine Rich repeats (2 copies)	1	0	27.00	407	447
LRR_1	Leucine Rich Repeat	0.52	2	20.60	407	427
LRR_6	Leucine Rich repeat	0.92	0	23.40	454	467
LRR_8	Leucine rich repeat	1.8E-08	24	27.00	454	514
LRR_4	Leucine Rich repeats (2 copies)	0.98	0	27.00	455	465
LRR_1	Leucine Rich Repeat	0.39	2	20.60	456	473
LRR_4	Leucine Rich repeats (2 copies)	3.5E-07	21	27.00	479	515
LRR_8	Leucine rich repeat	3.6E-09	27	27.00	480	538
LRR_6	Leucine Rich repeat	0.0068	7	23.40	502	517
LRR_9	Leucine-rich repeat	0.00051	10	30.50	502	604
LRR_1	Leucine Rich Repeat	0.0094	7	20.60	504	524
LRR_4	Leucine Rich repeats (2 copies)	5.6E-07	20	27.00	530	566
LRR_8	Leucine rich repeat	4.3E-13	39	27.00	550	610
LRR_6	Leucine Rich repeat	0.0023	8	23.40	550	565
LRR_1	Leucine Rich Repeat	0.00029	12	20.60	551	573
LRR_4	Leucine Rich repeats (2 copies)	9.1E-05	13	27.00	574	611
LRR_1	Leucine Rich Repeat	0.2	3	20.60	576	596
LRR_6	Leucine Rich repeat	0.021	5	23.40	599	613
LRR_1	Leucine Rich Repeat	0.0089	7	20.60	600	621
LRR_8	Leucine rich repeat	3.2E-10	30	27.00	616	658
LRR_6	Leucine Rich repeat	0.00044	11	23.40	621	636
LRR_4	Leucine Rich repeats (2 copies)	1.8E-08	25	27.00	622	662
LRR_1	Leucine Rich Repeat	9.3E-06	16	20.60	623	643
MitoNEET_N	Iron-containing outer mitochondrial membrane protein N-terminus	0.96	0	21.30	638	653
LRR_1	Leucine Rich Repeat	0.039	5	20.60	648	664
LRR_6	Leucine Rich repeat	0.0096	6	23.40	648	660
TMEM154	TMEM154 protein family	1.5E-06	18	30.30	687	745
Insulin_TMD	Insulin receptor trans-membrane segment	9.6E-08	22	33.40	705	737
EphA2_TM	Ephrin type-A receptor 2 transmembrane domain	0.00043	11	28.90	715	748
Pkinase	Protein kinase domain	0	160	20.40	779	1040
PK_Tyr_Ser-Thr	Protein tyrosine and serine/threonine kinase	0	153	23.10	781	1042
APH	Phosphotransferase enzyme family	0.14	2	22.40	813	873
Fructosamin_kin	Fructosamine kinase	0.018	4	20.00	815	859
PIP49_C	Pancreatitis induced protein 49 C terminal	0.00021	11	28.10	827	926
APH	Phosphotransferase enzyme family	6.2E-05	13	22.40	840	928
Fructosamin_kin	Fructosamine kinase	0.013	5	20.00	872	919
Pkinase_fungal	Fungal protein kinase	1.6E-05	14	24.10	900	952