c2pfam

AT4G15545.1 :

Domain Description Evalue Bits GA Start End
KfrA_N Plasmid replication region DNA-binding N-term 6.4E-05 15 24.10 5 89
Tektin Tektin family 5.5E-05 13 25.10 38 141
DUF4618 Domain of unknown function (DUF4618) 0.0012 10 34.90 38 99
TolA_bind_tri TolA binding protein trimerisation 0.022 6 30.10 43 80
Spc24 Spc24 subunit of Ndc80 0.17 4 22.00 49 90
YscO-like YscO-like protein 0.00067 11 27.00 50 90
ZapB Cell division protein ZapB 0.018 7 31.20 50 96
SlyX SlyX 0.0027 10 30.00 50 93
Crescentin Crescentin protein 5.3E-05 14 100.00 50 135
bZIP_1 bZIP transcription factor 0.00039 12 22.00 50 83
Myosin_tail_1 Myosin tail 2.2E-05 14 51.00 50 127
Shugoshin_N Shugoshin N-terminal coiled-coil region 0.00098 10 30.00 50 66
TMF_TATA_bd TATA element modulatory factor 1 TATA binding 9.1E-05 14 28.70 50 87
zf-C4H2 Zinc finger-containing protein 2.3E-05 16 27.20 51 201
Spc7 Spc7 kinetochore protein 3.7E-05 14 34.00 51 140
ATG16 Autophagy protein 16 (ATG16) 4.1E-05 15 35.00 51 115
FapA Flagellar Assembly Protein A 0.0003 11 36.70 51 145
TolA_bind_tri TolA binding protein trimerisation 0.026 6 30.10 51 98
GAS Growth-arrest specific micro-tubule binding 0.00013 13 32.30 52 135
APG6_N Apg6 coiled-coil region 0.00019 13 45.00 52 129
TMF_DNA_bd TATA element modulatory factor 1 DNA binding 0.0011 10 35.00 53 85
BRE1 BRE1 E3 ubiquitin ligase 8.7E-06 17 23.40 53 140
CENP-F_leu_zip Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 0.0015 10 30.00 53 89
FlaC_arch Flagella accessory protein C (FlaC) 0.0032 9 22.00 54 90
Seryl_tRNA_N Seryl-tRNA synthetase N-terminal domain 0.086 4 27.90 54 88
DivIVA DivIVA protein 0.081 4 23.40 54 90
Csm1_N Csm1 N-terminal domain 0.00083 11 26.30 55 93
DUF5082 Domain of unknown function (DUF5082) 0.087 4 33.70 56 87
MbeD_MobD MbeD/MobD like 0.3 3 21.10 56 85
Uso1_p115_C Uso1 / p115 like vesicle tethering protein, C terminal region 9.8E-05 14 22.20 56 130
Fez1 Fez1 8.5E-05 14 25.00 57 139
DivIC Septum formation initiator 0.028 6 24.00 57 87
UPF0242 Uncharacterised protein family (UPF0242) 0.0014 10 23.70 59 128
Cnn_1N Centrosomin N-terminal motif 1 0.071 5 28.50 60 92
ADIP Afadin- and alpha -actinin-Binding 4.5E-06 18 29.10 65 129
Seryl_tRNA_N Seryl-tRNA synthetase N-terminal domain 0.00053 12 27.90 69 139
GIT_CC GIT coiled-coil Rho guanine nucleotide exchange factor 0.34 2 28.30 73 88
MbeD_MobD MbeD/MobD like 0.0003 12 21.10 76 129
Cep57_CLD_2 Centrosome localisation domain of PPC89 0.022 6 27.00 79 111
ZapB Cell division protein ZapB 0.0015 10 31.20 83 135
TolA_bind_tri TolA binding protein trimerisation 0.057 5 30.10 84 130
Cnn_1N Centrosomin N-terminal motif 1 0.0004 12 28.50 91 129
GIT_CC GIT coiled-coil Rho guanine nucleotide exchange factor 0.0001 13 28.30 96 129
FlaC_arch Flagella accessory protein C (FlaC) 0.036 6 22.00 97 128
DivIC Septum formation initiator 0.016 6 24.00 101 128
DUF5082 Domain of unknown function (DUF5082) 0.0094 8 33.70 102 137
TMF_DNA_bd TATA element modulatory factor 1 DNA binding 0.0036 9 35.00 103 145
Csm1_N Csm1 N-terminal domain 0.051 5 26.30 105 130
DivIVA DivIVA protein 0.0017 10 23.40 105 142
bZIP_1 bZIP transcription factor 0.041 5 22.00 105 129
Shugoshin_N Shugoshin N-terminal coiled-coil region 0.03 6 30.00 106 128
Cep57_CLD_2 Centrosome localisation domain of PPC89 0.0054 8 27.00 109 136
SlyX SlyX 0.31 3 30.00 113 146
TMF_TATA_bd TATA element modulatory factor 1 TATA binding 0.8 1 28.70 115 135

337

KfrA_N
Tektin
DUF4618
TolA_bind_tri
Spc24
YscO-like
ZapB
SlyX
Crescentin
bZIP_1
Myosin_tail_1
Shugoshin_N
TMF_TATA_bd
zf-C4H2
Spc7
ATG16
FapA
TolA_bind_tri
GAS
APG6_N
TMF_DNA_bd
BRE1
CENP-F_leu_zip
FlaC_arch
Seryl_tRNA_N
DivIVA
Csm1_N
DUF5082
MbeD_MobD
Uso1_p115_C
Fez1
DivIC
UPF0242
Cnn_1N
ADIP
Seryl_tRNA_N
GIT_CC
MbeD_MobD
Cep57_CLD_2
ZapB
TolA_bind_tri
Cnn_1N
GIT_CC
FlaC_arch
DivIC
DUF5082
TMF_DNA_bd
Csm1_N
DivIVA
bZIP_1
Shugoshin_N
Cep57_CLD_2
SlyX
TMF_TATA_bd

References:

Csm1_N

DivIVA
9045828 The divIVA minicell locus of Bacillus subtilis. J Bacteriol 1997;179:1671-1683.
9846742 Unconventional organization of the division and cell wall gene cluster of Streptococcus pneumoniae. Microbiology 1998;144:3069-3078.

DivIC
8113187 Characterization of a cell division gene from Bacillus subtilis that is required for vegetative and sporulation septum formation. J Bacteriol 1994;176:1451-1459.

DUF5082

Spc7
15371542 The fission yeast kinetochore component Spc7 associates with the EB1 family member Mal3 and is required for kinetochore-spindle association. Mol Biol Cell 2004;15:5255-5267.

FapA

Seryl_tRNA_N
8654381 The crystal structure of the ternary complex of T.thermophilus seryl-tRNA synthetase with tRNA(Ser) and a seryl-adenylate analogue reveals a conformational switch in the active site. EMBO J 1996;15:2834-2842.

KfrA_N
9245806 Divergence and conservation of the partitioning and global regulation functions in the central control region of the IncP plasmids RK2 and R751. Microbiology. 1997;143:2167-2177.
1602476 kfrA gene of broad host range plasmid RK2 encodes a novel DNA-binding protein. J Mol Biol. 1992;225:651-660.

CENP-F_leu_zip
7542657 CENP-F is a protein of the nuclear matrix that assembles onto kinetochores at late G2 and is rapidly degraded after mitosis. J Cell Biol. 1995;130:507-518.
14555653 LEK1 is a potential inhibitor of pocket protein-mediated cellular processes. J Biol Chem. 2004;279:664-676.

bZIP_1

Crescentin

Fez1
10097140 The FEZ1 gene at chromosome 8p22 encodes a leucine-zipper protein, and its expression is altered in multiple human tumors. Proc Natl Acad Sci U S A 1999;96:3928-3933.
11504921 FEZ1/LZTS1 gene at 8p22 suppresses cancer cell growth and regulates mitosis. Proc Natl Acad Sci U S A 2001;98:10374-10379.

TMF_TATA_bd
1409643 Cloning and chromosomal mapping of a human immunodeficiency virus 1 "TATA" element modulatory factor. Proc Natl Acad Sci U S A. 1992;89:9372-9376.
15128430 TMF is a golgin that binds Rab6 and influences Golgi morphology. BMC Cell Biol. 2004;5:18.
18182439 Localization and domain characterization of Arabidopsis golgin candidates. J Exp Bot. 2007;58:4373-4386.

TMF_DNA_bd
9742951 Tyrosine phosphorylation of the TATA element modulatory factor by the FER nuclear tyrosine kinases. FEBS Lett. 1998;434:339-345.
1409643 Cloning and chromosomal mapping of a human immunodeficiency virus 1 "TATA" element modulatory factor. Proc Natl Acad Sci U S A. 1992;89:9372-9376.
15128430 TMF is a golgin that binds Rab6 and influences Golgi morphology. BMC Cell Biol. 2004;5:18.
18182439 Localization and domain characterization of Arabidopsis golgin candidates. J Exp Bot. 2007;58:4373-4386.

Spc24
11266451 The Ndc80p complex from Saccharomyces cerevisiae contains conserved centromere components and has a function in chromosome segregation. J Cell Biol 2001;152:349-360.

ZapB

GIT_CC

Uso1_p115_C
11927603 Sequential tethering of Golgins and catalysis of SNAREpin assembly by the vesicle-tethering protein p115. J Cell Biol 2002;157:45-62.
12077354 Vesicle tethering complexes in membrane traffic. J Cell Sci 2002;115:2627-2637.

Cnn_1N

ADIP
12446711 ADIP, a novel Afadin- and alpha-actinin-binding protein localized at cell-cell adherens junctions. J Biol Chem. 2003;278:4103-4111.
17486116 Gamma-tubulin complex-mediated anchoring of spindle microtubules to spindle-pole bodies requires Msd1 in fission yeast. Nat Cell Biol. 2007;9:646-653.

FlaC_arch
11250034 The archaeal flagellum: a different kind of prokaryotic motility structure. FEMS Microbiol Rev 2001;25:147-174.
11717274 Characterization of flagellum gene families of methanogenic archaea and localization of novel flagellum accessory proteins. J Bacteriol 2001;183:7154-7164.

DUF4618

ATG16
10406794 Apg16p is required for the function of the Apg12p-Apg5p conjugate in the yeast autophagy pathway. EMBO J. 1999;18:3888-3896.
17012802 Expression, purification and crystallization of the Atg5-Atg16 complex essential for autophagy. Acta Crystallograph Sect F Struct Biol Cryst Commun. 2006;62:1021-1023.

YscO-like

APG6_N

Shugoshin_N
14730319 The conserved kinetochore protein shugoshin protects centromeric cohesion during meiosis. Nature 2004;427:510-517.
16687935 Human Shugoshin mediates kinetochore-driven formation of kinetochore microtubules. Cell Cycle. 2006;5:1094-1101.
17322402 Shugoshin enables tension-generating attachment of kinetochores by loading Aurora to centromeres. Genes Dev. 2007;21:420-435.

BRE1
16337599 The human homolog of yeast BRE1 functions as a transcriptional coactivator through direct activator interactions. Mol Cell. 2005;20:759-770.

Myosin_tail_1
3783701 Complete nucleotide and encoded amino acid sequence of a mammalian myosin heavy chain gene. Evidence against intron-dependent evolution of the rod. J MOL BIOL 1986;190:291-317.

MbeD_MobD
2671664 Characterization of the ColE1 mobilization region and its protein products. Mol Gen Genet 1989;217:488-498.

TolA_bind_tri

Cep57_CLD_2

UPF0242

Tektin
8609631 Structural comparison of tektins and evidence for their determination of complex spacings in flagellar microtubules. J Mol Biol 1996;257:385-397.

zf-C4H2

SlyX

GAS

Domain	Description	Evalue	Bits	GA	Start	End
KfrA_N	Plasmid replication region DNA-binding N-term	6.4E-05	15	24.10	5	89
Tektin	Tektin family	5.5E-05	13	25.10	38	141
DUF4618	Domain of unknown function (DUF4618)	0.0012	10	34.90	38	99
TolA_bind_tri	TolA binding protein trimerisation	0.022	6	30.10	43	80
Spc24	Spc24 subunit of Ndc80	0.17	4	22.00	49	90
YscO-like	YscO-like protein	0.00067	11	27.00	50	90
ZapB	Cell division protein ZapB	0.018	7	31.20	50	96
SlyX	SlyX	0.0027	10	30.00	50	93
Crescentin	Crescentin protein	5.3E-05	14	100.00	50	135
bZIP_1	bZIP transcription factor	0.00039	12	22.00	50	83
Myosin_tail_1	Myosin tail	2.2E-05	14	51.00	50	127
Shugoshin_N	Shugoshin N-terminal coiled-coil region	0.00098	10	30.00	50	66
TMF_TATA_bd	TATA element modulatory factor 1 TATA binding	9.1E-05	14	28.70	50	87
zf-C4H2	Zinc finger-containing protein	2.3E-05	16	27.20	51	201
Spc7	Spc7 kinetochore protein	3.7E-05	14	34.00	51	140
ATG16	Autophagy protein 16 (ATG16)	4.1E-05	15	35.00	51	115
FapA	Flagellar Assembly Protein A	0.0003	11	36.70	51	145
TolA_bind_tri	TolA binding protein trimerisation	0.026	6	30.10	51	98
GAS	Growth-arrest specific micro-tubule binding	0.00013	13	32.30	52	135
APG6_N	Apg6 coiled-coil region	0.00019	13	45.00	52	129
TMF_DNA_bd	TATA element modulatory factor 1 DNA binding	0.0011	10	35.00	53	85
BRE1	BRE1 E3 ubiquitin ligase	8.7E-06	17	23.40	53	140
CENP-F_leu_zip	Leucine-rich repeats of kinetochore protein Cenp-F/LEK1	0.0015	10	30.00	53	89
FlaC_arch	Flagella accessory protein C (FlaC)	0.0032	9	22.00	54	90
Seryl_tRNA_N	Seryl-tRNA synthetase N-terminal domain	0.086	4	27.90	54	88
DivIVA	DivIVA protein	0.081	4	23.40	54	90
Csm1_N	Csm1 N-terminal domain	0.00083	11	26.30	55	93
DUF5082	Domain of unknown function (DUF5082)	0.087	4	33.70	56	87
MbeD_MobD	MbeD/MobD like	0.3	3	21.10	56	85
Uso1_p115_C	Uso1 / p115 like vesicle tethering protein, C terminal region	9.8E-05	14	22.20	56	130
Fez1	Fez1	8.5E-05	14	25.00	57	139
DivIC	Septum formation initiator	0.028	6	24.00	57	87
UPF0242	Uncharacterised protein family (UPF0242)	0.0014	10	23.70	59	128
Cnn_1N	Centrosomin N-terminal motif 1	0.071	5	28.50	60	92
ADIP	Afadin- and alpha -actinin-Binding	4.5E-06	18	29.10	65	129
Seryl_tRNA_N	Seryl-tRNA synthetase N-terminal domain	0.00053	12	27.90	69	139
GIT_CC	GIT coiled-coil Rho guanine nucleotide exchange factor	0.34	2	28.30	73	88
MbeD_MobD	MbeD/MobD like	0.0003	12	21.10	76	129
Cep57_CLD_2	Centrosome localisation domain of PPC89	0.022	6	27.00	79	111
ZapB	Cell division protein ZapB	0.0015	10	31.20	83	135
TolA_bind_tri	TolA binding protein trimerisation	0.057	5	30.10	84	130
Cnn_1N	Centrosomin N-terminal motif 1	0.0004	12	28.50	91	129
GIT_CC	GIT coiled-coil Rho guanine nucleotide exchange factor	0.0001	13	28.30	96	129
FlaC_arch	Flagella accessory protein C (FlaC)	0.036	6	22.00	97	128
DivIC	Septum formation initiator	0.016	6	24.00	101	128
DUF5082	Domain of unknown function (DUF5082)	0.0094	8	33.70	102	137
TMF_DNA_bd	TATA element modulatory factor 1 DNA binding	0.0036	9	35.00	103	145
Csm1_N	Csm1 N-terminal domain	0.051	5	26.30	105	130
DivIVA	DivIVA protein	0.0017	10	23.40	105	142
bZIP_1	bZIP transcription factor	0.041	5	22.00	105	129
Shugoshin_N	Shugoshin N-terminal coiled-coil region	0.03	6	30.00	106	128
Cep57_CLD_2	Centrosome localisation domain of PPC89	0.0054	8	27.00	109	136
SlyX	SlyX	0.31	3	30.00	113	146
TMF_TATA_bd	TATA element modulatory factor 1 TATA binding	0.8	1	28.70	115	135