c2pfam

AT4G16143.1 :

Domain Description Evalue Bits GA Start End
IBB Importin beta binding domain 3.7E-28 88 23.60 12 99
Arm Armadillo/beta-catenin-like repeat 4.3E-14 42 20.60 110 150
RICTOR_V Rapamycin-insensitive companion of mTOR, domain 5 0.15 2 27.00 120 150
HEAT HEAT repeat 0.057 4 23.50 122 151
Arm_2 Armadillo-like 0.0011 8 20.40 123 191
HEAT_2 HEAT repeats 1.3E-09 28 27.70 123 196
V-ATPase_H_C V-ATPase subunit H 0.029 4 20.80 124 189
HEAT_EZ HEAT-like repeat 6E-10 29 27.00 135 189
Adaptin_N Adaptin N terminal region 4.2E-07 19 20.30 137 320
HEAT_PBS PBS lyase HEAT-like repeat 0.4 2 20.90 138 150
RICTOR_V Rapamycin-insensitive companion of mTOR, domain 5 0.0039 7 27.00 142 192
CTNNBL Catenin-beta-like, Arm-motif containing nuclear 0.2 2 20.90 152 184
Arm Armadillo/beta-catenin-like repeat 3.1E-16 49 20.60 152 191
NopRA1 Nucleolar pre-ribosomal-associated protein 1 0.0089 5 29.60 161 187
HEAT HEAT repeat 6.8E-07 19 23.50 165 191
HEAT_PBS PBS lyase HEAT-like repeat 0.0019 9 20.90 179 199
RICTOR_V Rapamycin-insensitive companion of mTOR, domain 5 0.061 4 27.00 182 224
Arm Armadillo/beta-catenin-like repeat 1.6E-11 34 20.60 194 235
HEAT_2 HEAT repeats 9.1E-05 13 27.70 209 287
HEAT_EZ HEAT-like repeat 4.4E-08 24 27.00 224 274
HEAT_PBS PBS lyase HEAT-like repeat 0.77 1 20.90 224 254
Adaptin_N Adaptin N terminal region 2.9E-05 13 20.30 246 495
Arm Armadillo/beta-catenin-like repeat 1.9E-10 31 20.60 248 276
HEAT HEAT repeat 0.01 6 23.50 249 275
NopRA1 Nucleolar pre-ribosomal-associated protein 1 0.0014 8 29.60 249 281
HEAT_2 HEAT repeats 1.1E-06 19 27.70 250 355
V-ATPase_H_C V-ATPase subunit H 0.0011 9 20.80 251 317
CTNNBL Catenin-beta-like, Arm-motif containing nuclear 0.0025 8 20.90 264 307
Arm Armadillo/beta-catenin-like repeat 2.2E-12 37 20.60 279 317
HEAT_EZ HEAT-like repeat 0.044 4 27.00 288 316
V-ATPase_H_C V-ATPase subunit H 0.00024 11 20.80 289 359
HEAT HEAT repeat 0.00041 11 23.50 290 318
HEAT_2 HEAT repeats 8.1E-05 13 27.70 292 372
HEAT_EZ HEAT-like repeat 8.6E-05 13 27.00 309 359
Arm Armadillo/beta-catenin-like repeat 2.1E-11 33 20.60 321 361
Arm_2 Armadillo-like 0.00037 10 20.40 324 416
CTNNBL Catenin-beta-like, Arm-motif containing nuclear 0.57 0 20.90 327 343
V-ATPase_H_C V-ATPase subunit H 0.053 4 20.80 334 399
NopRA1 Nucleolar pre-ribosomal-associated protein 1 0.25 1 29.60 334 366
HEAT_2 HEAT repeats 0.00039 11 27.70 335 411
HEAT HEAT repeat 0.43 1 23.50 336 360
RICTOR_V Rapamycin-insensitive companion of mTOR, domain 5 0.78 0 27.00 349 385
Arm Armadillo/beta-catenin-like repeat 1.6E-14 43 20.60 363 402
HEAT_EZ HEAT-like repeat 0.0075 7 27.00 391 424
RICTOR_V Rapamycin-insensitive companion of mTOR, domain 5 0.8 0 27.00 391 424
Arm Armadillo/beta-catenin-like repeat 7.4E-11 32 20.60 406 444
CTNNBL Catenin-beta-like, Arm-motif containing nuclear 0.55 0 20.90 406 427
Arm_2 Armadillo-like 0.0011 8 20.40 460 497
CTNNBL Catenin-beta-like, Arm-motif containing nuclear 0.094 3 20.90 462 492
Arm_3 Atypical Arm repeat 1.1E-22 69 28.80 463 507
V-ATPase_H_C V-ATPase subunit H 0.08 3 20.80 464 496
HEAT_2 HEAT repeats 0.87 0 27.70 468 496

535

IBB
Arm
RICTOR_V
HEAT
Arm_2
HEAT_2
V-ATPase_H_C
HEAT_EZ
Adaptin_N
HEAT_PBS
RICTOR_V
CTNNBL
Arm
NopRA1
HEAT
HEAT_PBS
RICTOR_V
Arm
HEAT_2
HEAT_EZ
HEAT_PBS
Adaptin_N
Arm
HEAT
NopRA1
HEAT_2
V-ATPase_H_C
CTNNBL
Arm
HEAT_EZ
V-ATPase_H_C
HEAT
HEAT_2
HEAT_EZ
Arm
Arm_2
CTNNBL
V-ATPase_H_C
NopRA1
HEAT_2
HEAT
RICTOR_V
Arm
HEAT_EZ
RICTOR_V
Arm
CTNNBL
Arm_2
CTNNBL
Arm_3
V-ATPase_H_C
HEAT_2

References:

RICTOR_V

V-ATPase_H_C
10954728 Regulation of yeast ectoapyrase ynd1p activity by activator subunit Vma13p of vacuolar H+-ATPase. J Biol Chem 2000;275:35592-35599.
18708638 Functional characterization of the N-terminal domain of subunit H (Vma13p) of the yeast vacuolar ATPase. J Biol Chem. 2008; [Epub ahead of print]
16141210 Structural and functional separation of the N- and C-terminal domains of the yeast V-ATPase subunit H. J Biol Chem. 2005;280:36978-36985.

Arm_2

Arm
9298899 Three-dimensional structure of the armadillo repeat region of beta-catenin. Cell 1997;90:871-882.
8573337 Signal transduction of beta-catenin. Curr Opin Cell Biol 1995;7:634-640.
9309175 Armadillo and dTCF: a marriage made in the nucleus. Curr Opin Genet Dev 1997;7:459-466.
8259519 Association of the APC tumor suppressor protein with catenins. Science 1993;262:1734-1737.
8259518 Association of the APC gene product with beta-catenin. Science 1993;262:1731-1734.
2261639 The segment polarity gene armadillo encodes a functionally modular protein that is the Drosophila homolog of human plakoglobin. Cell 1990;63:1167-1176.

Adaptin_N
9261055 Linking cargo to vesicle formation: receptor tail interactions with coat proteins. Curr Opin Cell Biol 1997;9:488-495.
2495531 Structural and functional division into two domains of the large (100- to 115-kDa)chains of the clathrin-associated protein complex AP-2. Proc Natl Acad Sci U S A 1989;86:2612-2616.

IBB
9695948 Crystallographic analysis of the recognition of a nuclear localization signal by the nuclear import factor karyopherin alpha. Cell 1998;94:193-204.
9612083 Importins and exportins: how to get in and out of the nucleus [published erratum appears in Trends Biochem Sci 1998 Jul;23(7):235] Trends Biochem Sci 1998;23:185-189.
9582265 Transport into and out of the cell nucleus. EMBO J 1998;17:2721-2727.
8692858 The binding site of karyopherin alpha for karyopherin beta overlaps with a nuclear localization sequence. Proc Natl Acad Sci U S A 1996;93:6572-6576.
8617226 A 41 amino acid motif in importin-alpha confers binding to importin- beta and hence transit into the nucleus. EMBO J 1996;15:1810-1817.

HEAT_PBS
8132596 Oligomeric structure, enzyme kinetics, and substrate specificity of the phycocyanin alpha subunit phycocyanobilin lyase. J Biol Chem 1994;269:8686-8694.
9023176 A role for cpeYZ in cyanobacterial phycoerythrin biosynthesis. J Bacteriol 1997;179:998-1006.
10708746 Novel activity of a phycobiliprotein lyase: both the attachment of phycocyanobilin and the isomerization to phycoviolobilin are catalyzed by the proteins PecE and PecF encoded by the phycoerythrocyanin operon. FEBS Lett 2000;469:9-13.
9882677 A polypeptide with similarity to phycocyanin alpha-subunit phycocyanobilin lyase involved in degradation of phycobilisomes. J Bacteriol 1999;181:610-617.

HEAT
7550332 HEAT repeats in the Huntington's disease protein. Nat Genet 1995;11:115-116.
9989501 The structure of the protein phosphatase 2A PR65/A subunit reveals the conformation of its 15 tandemly repeated HEAT motifs. Cell 1999;96:99-110.

CTNNBL

HEAT_EZ

HEAT_2

NopRA1

Arm_3

Domain	Description	Evalue	Bits	GA	Start	End
IBB	Importin beta binding domain	3.7E-28	88	23.60	12	99
Arm	Armadillo/beta-catenin-like repeat	4.3E-14	42	20.60	110	150
RICTOR_V	Rapamycin-insensitive companion of mTOR, domain 5	0.15	2	27.00	120	150
HEAT	HEAT repeat	0.057	4	23.50	122	151
Arm_2	Armadillo-like	0.0011	8	20.40	123	191
HEAT_2	HEAT repeats	1.3E-09	28	27.70	123	196
V-ATPase_H_C	V-ATPase subunit H	0.029	4	20.80	124	189
HEAT_EZ	HEAT-like repeat	6E-10	29	27.00	135	189
Adaptin_N	Adaptin N terminal region	4.2E-07	19	20.30	137	320
HEAT_PBS	PBS lyase HEAT-like repeat	0.4	2	20.90	138	150
RICTOR_V	Rapamycin-insensitive companion of mTOR, domain 5	0.0039	7	27.00	142	192
CTNNBL	Catenin-beta-like, Arm-motif containing nuclear	0.2	2	20.90	152	184
Arm	Armadillo/beta-catenin-like repeat	3.1E-16	49	20.60	152	191
NopRA1	Nucleolar pre-ribosomal-associated protein 1	0.0089	5	29.60	161	187
HEAT	HEAT repeat	6.8E-07	19	23.50	165	191
HEAT_PBS	PBS lyase HEAT-like repeat	0.0019	9	20.90	179	199
RICTOR_V	Rapamycin-insensitive companion of mTOR, domain 5	0.061	4	27.00	182	224
Arm	Armadillo/beta-catenin-like repeat	1.6E-11	34	20.60	194	235
HEAT_2	HEAT repeats	9.1E-05	13	27.70	209	287
HEAT_EZ	HEAT-like repeat	4.4E-08	24	27.00	224	274
HEAT_PBS	PBS lyase HEAT-like repeat	0.77	1	20.90	224	254
Adaptin_N	Adaptin N terminal region	2.9E-05	13	20.30	246	495
Arm	Armadillo/beta-catenin-like repeat	1.9E-10	31	20.60	248	276
HEAT	HEAT repeat	0.01	6	23.50	249	275
NopRA1	Nucleolar pre-ribosomal-associated protein 1	0.0014	8	29.60	249	281
HEAT_2	HEAT repeats	1.1E-06	19	27.70	250	355
V-ATPase_H_C	V-ATPase subunit H	0.0011	9	20.80	251	317
CTNNBL	Catenin-beta-like, Arm-motif containing nuclear	0.0025	8	20.90	264	307
Arm	Armadillo/beta-catenin-like repeat	2.2E-12	37	20.60	279	317
HEAT_EZ	HEAT-like repeat	0.044	4	27.00	288	316
V-ATPase_H_C	V-ATPase subunit H	0.00024	11	20.80	289	359
HEAT	HEAT repeat	0.00041	11	23.50	290	318
HEAT_2	HEAT repeats	8.1E-05	13	27.70	292	372
HEAT_EZ	HEAT-like repeat	8.6E-05	13	27.00	309	359
Arm	Armadillo/beta-catenin-like repeat	2.1E-11	33	20.60	321	361
Arm_2	Armadillo-like	0.00037	10	20.40	324	416
CTNNBL	Catenin-beta-like, Arm-motif containing nuclear	0.57	0	20.90	327	343
V-ATPase_H_C	V-ATPase subunit H	0.053	4	20.80	334	399
NopRA1	Nucleolar pre-ribosomal-associated protein 1	0.25	1	29.60	334	366
HEAT_2	HEAT repeats	0.00039	11	27.70	335	411
HEAT	HEAT repeat	0.43	1	23.50	336	360
RICTOR_V	Rapamycin-insensitive companion of mTOR, domain 5	0.78	0	27.00	349	385
Arm	Armadillo/beta-catenin-like repeat	1.6E-14	43	20.60	363	402
HEAT_EZ	HEAT-like repeat	0.0075	7	27.00	391	424
RICTOR_V	Rapamycin-insensitive companion of mTOR, domain 5	0.8	0	27.00	391	424
Arm	Armadillo/beta-catenin-like repeat	7.4E-11	32	20.60	406	444
CTNNBL	Catenin-beta-like, Arm-motif containing nuclear	0.55	0	20.90	406	427
Arm_2	Armadillo-like	0.0011	8	20.40	460	497
CTNNBL	Catenin-beta-like, Arm-motif containing nuclear	0.094	3	20.90	462	492
Arm_3	Atypical Arm repeat	1.1E-22	69	28.80	463	507
V-ATPase_H_C	V-ATPase subunit H	0.08	3	20.80	464	496
HEAT_2	HEAT repeats	0.87	0	27.70	468	496