c2pfam

AT4G18360.1 :

Domain Description Evalue Bits GA Start End
FMN_dh FMN-dependent dehydrogenase 0 462 22.00 13 355
IMPDH IMP dehydrogenase / GMP reductase domain 0.66 -2 24.00 53 95
Dus Dihydrouridine synthase (Dus) 0.62 -2 20.30 137 154
DUF561 Protein of unknown function (DUF561) 0.00081 8 21.60 167 251
Dus Dihydrouridine synthase (Dus) 0.005 5 20.30 209 252
TMP-TENI Thiamine monophosphate synthase/TENI 0.00014 11 20.80 209 252
DHO_dh Dihydroorotate dehydrogenase 0.55 -1 20.30 210 247
ThiG Thiazole biosynthesis protein ThiG 0.0005 9 19.90 216 258
His_biosynth Histidine biosynthesis protein 0.3 0 22.90 220 261
DUF561 Protein of unknown function (DUF561) 0.00034 9 21.60 220 277
NMO Nitronate monooxygenase 4E-11 32 28.00 228 351
PA PA domain 0.00059 10 21.30 235 256
Dus Dihydrouridine synthase (Dus) 0.00014 11 20.30 239 311
DUF561 Protein of unknown function (DUF561) 0.0061 5 21.60 258 309
TMP-TENI Thiamine monophosphate synthase/TENI 0.028 3 20.80 263 307
IMPDH IMP dehydrogenase / GMP reductase domain 4.3E-09 25 24.00 265 309
DHO_dh Dihydroorotate dehydrogenase 2.6E-05 13 20.30 266 309
His_biosynth Histidine biosynthesis protein 5.8E-06 15 22.90 268 309
ThiG Thiazole biosynthesis protein ThiG 3.6E-05 13 19.90 269 307
Glu_synthase Conserved region in glutamate synthase 1.2E-07 21 19.80 276 315

368

FMN_dh
IMPDH
Dus
DUF561
Dus
TMP-TENI
DHO_dh
ThiG
His_biosynth
DUF561
NMO
PA
Dus
DUF561
TMP-TENI
IMPDH
DHO_dh
His_biosynth
ThiG
Glu_synthase

References:

Dus
12003496 A conserved family of Saccharomyces cerevisiae synthases effects dihydrouridine modification of tRNA. RNA 2002;8:370-381.

Glu_synthase
8923741 Sequence of the GLT1 gene from Saccharomyces cerevisiae reveals the domain structure of yeast glutamate synthase. Yeast 1996;12:1359-1366.

DUF561

His_biosynth
9332345 Paralogous histidine biosynthetic genes: evolutionary analysis of the Saccharomyces cerevisiae HIS6 and HIS7 genes. Gene 1997;197:9-17.
8028028 The evolution of the histidine biosynthetic genes in prokaryotes: a common ancestor for the hisA and hisF genes. J Mol Evol 1994;38:489-495.
8028028 The evolution of the histidine biosynthetic genes in prokaryotes: a common ancestor for the hisA and hisF genes. J Mol Evol 1994;38:489-495.
11054297 Homology among (betaalpha)(8) barrels: implications for the evolution of metabolic pathways. J Mol Biol 2000;303:627-641.

NMO

ThiG
9371431 Expression of thiamin biosynthetic genes (thiCOGE) and production of symbiotic terminal oxidase cbb3 in Rhizobium etli. J Bacteriol 1997;179:6887-6893.

DHO_dh
9655329 The crystal structure of Lactococcus lactis dihydroorotate dehydrogenase A complexed with the enzyme reaction product throws light on its enzymatic function. Protein Sci 1998;7:1269-1279.

IMPDH
9271497 Crystal structure of Tritrichomonas foetus inosine-5'-monophosphate dehydrogenase and the enzyme-product complex. Biochemistry 1997;36:10666-10674.
10200156 Characteristics and crystal structure of bacterial inosine-5'-monophosphate dehydrogenase. Biochemistry 1999;38:4691-4700.

FMN_dh
2681790 Refined structure of spinach glycolate oxidase at 2 A resolution. J Mol Biol 1989;209:151-166.
2329585 Molecular structure of flavocytochrome b2 at 2.4 A resolution. J Mol Biol 1990;212:837-863.

TMP-TENI
9139923 Characterization of the Bacillus subtilis thiC operon involved in thiamine biosynthesis. J Bacteriol 1997;179:3030-3035.

PA
11246007 The protease-associated domain: a homology domain associated with multiple classes of proteases. Trends Biochem Sci 2001;26:147-148.

Domain	Description	Evalue	Bits	GA	Start	End
FMN_dh	FMN-dependent dehydrogenase	0	462	22.00	13	355
IMPDH	IMP dehydrogenase / GMP reductase domain	0.66	-2	24.00	53	95
Dus	Dihydrouridine synthase (Dus)	0.62	-2	20.30	137	154
DUF561	Protein of unknown function (DUF561)	0.00081	8	21.60	167	251
Dus	Dihydrouridine synthase (Dus)	0.005	5	20.30	209	252
TMP-TENI	Thiamine monophosphate synthase/TENI	0.00014	11	20.80	209	252
DHO_dh	Dihydroorotate dehydrogenase	0.55	-1	20.30	210	247
ThiG	Thiazole biosynthesis protein ThiG	0.0005	9	19.90	216	258
His_biosynth	Histidine biosynthesis protein	0.3	0	22.90	220	261
DUF561	Protein of unknown function (DUF561)	0.00034	9	21.60	220	277
NMO	Nitronate monooxygenase	4E-11	32	28.00	228	351
PA	PA domain	0.00059	10	21.30	235	256
Dus	Dihydrouridine synthase (Dus)	0.00014	11	20.30	239	311
DUF561	Protein of unknown function (DUF561)	0.0061	5	21.60	258	309
TMP-TENI	Thiamine monophosphate synthase/TENI	0.028	3	20.80	263	307
IMPDH	IMP dehydrogenase / GMP reductase domain	4.3E-09	25	24.00	265	309
DHO_dh	Dihydroorotate dehydrogenase	2.6E-05	13	20.30	266	309
His_biosynth	Histidine biosynthesis protein	5.8E-06	15	22.90	268	309
ThiG	Thiazole biosynthesis protein ThiG	3.6E-05	13	19.90	269	307
Glu_synthase	Conserved region in glutamate synthase	1.2E-07	21	19.80	276	315