c2pfam

AT4G21800.1 :

Domain Description Evalue Bits GA Start End
AAA_7 P-loop containing dynein motor region 0.00029 11 25.80 16 74
Adeno_IVa2 Adenovirus IVa2 protein 2.2E-06 18 20.10 26 85
G-alpha G-protein alpha subunit 0.0029 8 20.10 34 61
Pox_A32 Poxvirus A32 protein 9.7E-05 13 20.50 36 64
Arf ADP-ribosylation factor family 0.00098 10 20.30 37 66
T2SSE Type II/IV secretion system protein 0.0011 9 24.90 37 63
Zeta_toxin Zeta toxin 2.2E-05 15 20.10 38 79
AAA_23 AAA domain 0.015 7 27.00 40 58
AAA_16 AAA ATPase domain 9.8E-05 14 32.60 41 86
NB-ARC NB-ARC domain 9.3E-05 13 23.50 41 73
RsgA_GTPase RsgA GTPase 0.015 6 30.00 42 64
AAA_24 AAA domain 3.7E-05 15 27.00 42 150
SRP54 SRP54-type protein, GTPase domain 0.00081 10 20.50 42 75
GTP_EFTU Elongation factor Tu GTP binding domain 2.5E-07 21 20.20 42 281
cobW CobW/HypB/UreG, nucleotide-binding domain 4.6E-07 21 20.70 43 226
AAA_33 AAA domain 3.9E-05 15 27.00 43 78
SRPRB Signal recognition particle receptor beta subunit 0.00014 12 20.50 43 66
FtsK_SpoIIIE FtsK/SpoIIIE family 0.00017 12 21.20 43 63
MobB Molybdopterin guanine dinucleotide synthesis protein B 0.0005 11 21.60 43 64
MeaB Methylmalonyl Co-A mutase-associated GTPase MeaB 0.011 6 23.10 44 81
AAA_18 AAA domain 0.00018 13 29.40 44 75
NACHT NACHT domain 3.3E-05 15 20.40 44 64
Roc Ras of Complex, Roc, domain of DAPkinase 1.5E-05 16 27.00 44 71
MMR_HSR1 GTPase of unknown function 3.9E-06 18 24.50 44 212
Ras Ras family 0.00017 12 20.80 44 74
FeoB_N Ferrous iron transport protein B 0.55 1 21.20 44 62
Dynamin_N Dynamin family 1.5E-05 16 21.00 44 150
ATP_bind_1 Conserved hypothetical ATP binding protein 0 264 20.20 46 284
Ras Ras family 0.0093 7 20.80 124 232
SRP54 SRP54-type protein, GTPase domain 0.056 4 20.50 132 150
SRPRB Signal recognition particle receptor beta subunit 0.054 4 20.50 135 217
FeoB_N Ferrous iron transport protein B 1.1E-05 16 21.20 136 219
Frizzled Frizzled/Smoothened family membrane region 0.00033 11 20.00 159 204
RsgA_GTPase RsgA GTPase 0.015 6 30.00 199 249
G-alpha G-protein alpha subunit 0.057 4 20.10 202 242
MeaB Methylmalonyl Co-A mutase-associated GTPase MeaB 0.041 4 23.10 261 319
AAA_23 AAA domain 0.1 4 27.00 267 322
TFIIA Transcription factor IIA, alpha/beta subunit 0.0051 8 29.20 289 374
DUF3295 Protein of unknown function (DUF3295) 0.013 6 20.30 293 372
T2SSE Type II/IV secretion system protein 0.4 1 24.90 324 359

379

AAA_7
Adeno_IVa2
G-alpha
Pox_A32
Arf
T2SSE
Zeta_toxin
AAA_23
AAA_16
NB-ARC
RsgA_GTPase
AAA_24
SRP54
GTP_EFTU
cobW
AAA_33
SRPRB
FtsK_SpoIIIE
MobB
MeaB
AAA_18
NACHT
Roc
MMR_HSR1
Ras
FeoB_N
Dynamin_N
ATP_bind_1
Ras
SRP54
SRPRB
FeoB_N
Frizzled
RsgA_GTPase
G-alpha
MeaB
AAA_23
TFIIA
DUF3295
T2SSE

References:

MMR_HSR1
8180467 Structure and evolution of a member of a new subfamily of GTP-binding proteins mapping to the human MHC class I region. Mamm Genome 1994;5:100-105.

DUF3295

SRP54
9002525 Crystal structure of the NG domain from the signal-recognition particle receptor FtsY. Nature 1997;385:365-368.

SRPRB
7844142 The beta subunit of the signal recognition particle receptor is a transmembrane GTPase that anchors the alpha subunit, a peripheral membrane GTPase, to the endoplasmic reticulum membrane. J Cell Biol. 1995;128:273-282.

Zeta_toxin
12571357 Crystal structure of the plasmid maintenance system epsilon/zeta: functional mechanism of toxin zeta and inactivation by epsilon 2 zeta 2 complex formation. Proc Natl Acad Sci U S A 2003;100:1661-1666.

FtsK_SpoIIIE
7592387 A new Escherichia coli cell division gene, ftsK. J Bacteriol 1995;177:6211-6222.
8160014 Bacillus subtilis spoIIIE protein required for DNA segregation during asymmetric cell division. Science 1994;264:572-575.

ATP_bind_1

Frizzled
8717036 A new member of the frizzled family from Drosophila functions as a Wingless receptor. Nature 1996;382:225-230.
15239825 The Frizzled family: receptors for multiple signal transduction pathways. Genome Biol 2004;5:234.
9811578 In vivo evidence that Patched and Smoothened constitute distinct binding and transducing components of a Hedgehog receptor complex. Development 1998;125:4943-4948.
9852758 The frizzled motif: in how many different protein families does it occur?. Trends Biochem Sci 1998;23:415-417.

MeaB

Arf
7990966 Structure of the human ADP-ribosylation factor 1 complexed with GDP. Nature 1994;372:704-708.
7759471 Structure and function of ARF proteins: Activators of cholera toxin and critical components of intracellular vesicular transport processes. J. Biol. Chem. 1995;270:12327-12330.
7770914 Arf proteins: the membrane traffic police? Trends Biochem Sci 1995;20:147-150.
1899243 Human ADP-ribosylation factors. A functionally conserved family of GTP-binding proteins. J Biol Chem 1991;266:2606-2614.

Ras
11387043 The Rab GTPase family. Genome Biol 2001;2:REVIEWS3007.

FeoB_N
8407793 Characterization of the ferrous iron uptake system of Escherichia coli. J Bacteriol 1993;175:6212-6219.

AAA_7

Roc

NACHT
10782090 The NACHT family - a new group of predicted NTPases implicated in apoptosis and MHC transcription activation. Trends Biochem Sci 2000;25:223-224.

AAA_33

Dynamin_N
8939066 Dynamin GTPase, a force-generating molecular switch. Bioessays 1996;18:885-893.
2144893 Molecular cloning of the microtubule-associated mechanochemical enzyme dynamin reveals homology with a new family of GTP-binding proteins. Nature 1990;347:256-261.

G-alpha
8073283 Structures of active conformations of Gi alpha 1 and the mechanism of GTP hydrolysis. Science 1994;265:1405-1412.
8851656 How G proteins work: a continuing story. Trends Biochem Sci 1996;21:41-44.

AAA_24

AAA_23

Pox_A32
9621036 DNA packaging mutant: repression of the vaccinia virus A32 gene results in noninfectious, DNA-deficient, spherical, enveloped particles. J Virol 1998;72:5769-5780.

AAA_18

AAA_16

TFIIA
11089979 A transcription reinitiation intermediate that is stabilized by activator. Nature 2000;408:225-229.
8224848 A single cDNA, hTFIIA/alpha, encodes both the p35 and p19 subunits of human TFIIA. Genes Dev 1993;7:2220-2234.
8610010 Crystal structure of a yeast TFIIA/TBP/DNA complex. Nature 1996;381:127-151.

Adeno_IVa2
10684284 Interaction of the adenovirus IVa2 protein with viral packaging sequences. J Virol 2000;74:2687-2693.
8207818 The product of the adenovirus intermediate gene IVa2 is a transcriptional activator of the major late promoter. J Virol 1994;68:4450-4457.

MobB

T2SSE

cobW
9140970 The HypB protein from Bradyrhizobium japonicum can store nickel and is required for the nickel-dependent transcriptional regulation of hydrogenase. Mol Microbiol 1997;24:119-128.
9209019 Characterization of UreG, identification of a UreD-UreF-UreG complex, and evidence suggesting that a nucleotide-binding site in UreG is required for in vivo metallocenter assembly of Klebsiella aerogenes urease. J Bacteriol 1997;179:4081-4086.
8423137 The product of the hypB gene, which is required for nickel incorporation into hydrogenases, is a novel guanine nucleotide-binding protein. J Bacteriol 1993;175:630-635.
1624427 Klebsiella aerogenes urease gene cluster: sequence of ureD and demonstration that four accessory genes (ureD, ureE, ureF, and ureG) are involved in nickel metallocenter biosynthesis. J Bacteriol 1992;174:4324-4330.
1655697 Nucleotide sequence and genetic analysis of a 13.1-kilobase-pair Pseudomonas denitrificans DNA fragment containing five cob genes and identification of structural genes encoding Cob(I)alamin adenosyltransferase, cobyric acid synthase, and bifunctional cob J Bacteriol 1991;173:6074-6087.

GTP_EFTU
9311785 Visualization of elongation factor Tu on the Escherichia coli ribosome. Nature 1997;389:403-406.

NB-ARC
9545207 The NB-ARC domain: a novel signalling motif shared by plant resistance gene products and regulators of cell death in animals. Curr Biol 1998;8:226-227.

RsgA_GTPase

Domain	Description	Evalue	Bits	GA	Start	End
AAA_7	P-loop containing dynein motor region	0.00029	11	25.80	16	74
Adeno_IVa2	Adenovirus IVa2 protein	2.2E-06	18	20.10	26	85
G-alpha	G-protein alpha subunit	0.0029	8	20.10	34	61
Pox_A32	Poxvirus A32 protein	9.7E-05	13	20.50	36	64
Arf	ADP-ribosylation factor family	0.00098	10	20.30	37	66
T2SSE	Type II/IV secretion system protein	0.0011	9	24.90	37	63
Zeta_toxin	Zeta toxin	2.2E-05	15	20.10	38	79
AAA_23	AAA domain	0.015	7	27.00	40	58
AAA_16	AAA ATPase domain	9.8E-05	14	32.60	41	86
NB-ARC	NB-ARC domain	9.3E-05	13	23.50	41	73
RsgA_GTPase	RsgA GTPase	0.015	6	30.00	42	64
AAA_24	AAA domain	3.7E-05	15	27.00	42	150
SRP54	SRP54-type protein, GTPase domain	0.00081	10	20.50	42	75
GTP_EFTU	Elongation factor Tu GTP binding domain	2.5E-07	21	20.20	42	281
cobW	CobW/HypB/UreG, nucleotide-binding domain	4.6E-07	21	20.70	43	226
AAA_33	AAA domain	3.9E-05	15	27.00	43	78
SRPRB	Signal recognition particle receptor beta subunit	0.00014	12	20.50	43	66
FtsK_SpoIIIE	FtsK/SpoIIIE family	0.00017	12	21.20	43	63
MobB	Molybdopterin guanine dinucleotide synthesis protein B	0.0005	11	21.60	43	64
MeaB	Methylmalonyl Co-A mutase-associated GTPase MeaB	0.011	6	23.10	44	81
AAA_18	AAA domain	0.00018	13	29.40	44	75
NACHT	NACHT domain	3.3E-05	15	20.40	44	64
Roc	Ras of Complex, Roc, domain of DAPkinase	1.5E-05	16	27.00	44	71
MMR_HSR1	GTPase of unknown function	3.9E-06	18	24.50	44	212
Ras	Ras family	0.00017	12	20.80	44	74
FeoB_N	Ferrous iron transport protein B	0.55	1	21.20	44	62
Dynamin_N	Dynamin family	1.5E-05	16	21.00	44	150
ATP_bind_1	Conserved hypothetical ATP binding protein	0	264	20.20	46	284
Ras	Ras family	0.0093	7	20.80	124	232
SRP54	SRP54-type protein, GTPase domain	0.056	4	20.50	132	150
SRPRB	Signal recognition particle receptor beta subunit	0.054	4	20.50	135	217
FeoB_N	Ferrous iron transport protein B	1.1E-05	16	21.20	136	219
Frizzled	Frizzled/Smoothened family membrane region	0.00033	11	20.00	159	204
RsgA_GTPase	RsgA GTPase	0.015	6	30.00	199	249
G-alpha	G-protein alpha subunit	0.057	4	20.10	202	242
MeaB	Methylmalonyl Co-A mutase-associated GTPase MeaB	0.041	4	23.10	261	319
AAA_23	AAA domain	0.1	4	27.00	267	322
TFIIA	Transcription factor IIA, alpha/beta subunit	0.0051	8	29.20	289	374
DUF3295	Protein of unknown function (DUF3295)	0.013	6	20.30	293	372
T2SSE	Type II/IV secretion system protein	0.4	1	24.90	324	359