c2pfam

AT4G34200.1 :

Domain Description Evalue Bits GA Start End
2-Hacid_dh D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 7.5E-36 112 24.60 64 373
NAD_binding_2 NAD binding domain of 6-phosphogluconate dehydrogenase 0.54 0 21.00 147 173
UDPG_MGDP_dh_C UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain 0.14 2 24.60 161 193
2-Hacid_dh_C D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 0 211 25.10 166 341
AdoHcyase_NAD S-adenosyl-L-homocysteine hydrolase, NAD binding domain 1.6E-08 24 21.00 196 290
IlvN Acetohydroxy acid isomeroreductase, catalytic domain 1E-08 24 20.60 198 299
XdhC_C XdhC Rossmann domain 3.8E-05 13 29.70 203 306
NAD_binding_2 NAD binding domain of 6-phosphogluconate dehydrogenase 7.4E-05 12 21.00 203 291
UDPG_MGDP_dh_C UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain 0.00028 11 24.60 215 261
ACT ACT domain 6.9E-11 31 20.80 531 593

603

2-Hacid_dh
NAD_binding_2
UDPG_MGDP_dh_C
2-Hacid_dh_C
AdoHcyase_NAD
IlvN
XdhC_C
NAD_binding_2
UDPG_MGDP_dh_C
ACT

References:

IlvN
9218783 The crystal structure of plant acetohydroxy acid isomeroreductase complexed with NADPH, two magnesium ions and a herbicidal transition state analog determined at 1.65 A resolution. EMBO J 1997;16:3405-3415.

NAD_binding_2

UDPG_MGDP_dh_C
2470755 Purification and characterization of guanosine diphospho-D-mannose dehydrogenase. A key enzyme in the biosynthesis of alginate by Pseudomonas aeruginosa. J Biol Chem 1989;264:9380-9385.
9013585 Properties and kinetic analysis of UDP-glucose dehydrogenase from group A streptococci. Irreversible inhibition by UDP-chloroacetol. J Biol Chem 1997;272:3416-3422.

XdhC_C

ACT
7719856 The allosteric ligand site in the Vmax-type cooperative enzyme phosphoglycerate dehydrogenase. Nat Struct Biol 1995;2:69-76.
10222208 Gleaning non-trivial structural, functional and evolutionary information about proteins by iterative database searches. J Mol Biol 1999;287:1023-1040.

2-Hacid_dh_C
9126843 Crystal structure of a ternary complex of D-2-hydroxyisocaproate dehydrogenase from Lactobacillus casei, NAD+ and 2-oxoisocaproate at 1.9 A resolution. J Mol Biol 1997;267:640-660.

2-Hacid_dh
9126843 Crystal structure of a ternary complex of D-2-hydroxyisocaproate dehydrogenase from Lactobacillus casei, NAD+ and 2-oxoisocaproate at 1.9 A resolution. J Mol Biol 1997;267:640-660.

AdoHcyase_NAD

Domain	Description	Evalue	Bits	GA	Start	End
2-Hacid_dh	D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain	7.5E-36	112	24.60	64	373
NAD_binding_2	NAD binding domain of 6-phosphogluconate dehydrogenase	0.54	0	21.00	147	173
UDPG_MGDP_dh_C	UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain	0.14	2	24.60	161	193
2-Hacid_dh_C	D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain	0	211	25.10	166	341
AdoHcyase_NAD	S-adenosyl-L-homocysteine hydrolase, NAD binding domain	1.6E-08	24	21.00	196	290
IlvN	Acetohydroxy acid isomeroreductase, catalytic domain	1E-08	24	20.60	198	299
XdhC_C	XdhC Rossmann domain	3.8E-05	13	29.70	203	306
NAD_binding_2	NAD binding domain of 6-phosphogluconate dehydrogenase	7.4E-05	12	21.00	203	291
UDPG_MGDP_dh_C	UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain	0.00028	11	24.60	215	261
ACT	ACT domain	6.9E-11	31	20.80	531	593