c2pfam

AT5G02150.1 :

Domain Description Evalue Bits GA Start End
Fes1 Nucleotide exchange factor Fes1 1.1E-11 35 21.40 10 95
V-ATPase_H_C V-ATPase subunit H 5.2E-05 13 20.80 10 129
GP67 Gene product 67 0.00022 12 27.00 33 52
ENTH ENTH domain 0.94 -1 20.80 36 62
MMS19_N NER and RNAPII transcription protein n terminal 1 -1 21.40 54 87
SIL1 Nucleotide exchange factor SIL1 6E-08 22 35.50 62 218
EF1_GNE EF-1 guanine nucleotide exchange domain 0.0027 8 20.80 69 93
MOR2-PAG1_C Cell morphogenesis C-terminal 0.033 4 25.00 96 151
V-ATPase_H_C V-ATPase subunit H 0.00014 12 20.80 98 172
Arm Armadillo/beta-catenin-like repeat 0.8 0 20.60 99 123
HEAT HEAT repeat 0.033 5 23.50 104 128
MMS19_N NER and RNAPII transcription protein n terminal 0.0012 8 21.40 106 173
ENTH ENTH domain 0.57 0 20.80 109 126
HEAT_EZ HEAT-like repeat 0.001 10 27.00 115 169
Atx10homo_assoc Spinocerebellar ataxia type 10 protein domain 0.00026 11 22.40 119 174
Arm Armadillo/beta-catenin-like repeat 0.028 5 20.60 146 169
HEAT HEAT repeat 0.032 5 23.50 146 170
RTP1_C1 Required for nuclear transport of RNA pol II C-terminus 1 0.09 3 25.90 151 173
RTP1_C1 Required for nuclear transport of RNA pol II C-terminus 1 0.0062 7 25.90 151 217
MMS19_N NER and RNAPII transcription protein n terminal 0.002 7 21.40 189 275
MOR2-PAG1_C Cell morphogenesis C-terminal 0.0003 11 25.00 193 250
RTP1_C1 Required for nuclear transport of RNA pol II C-terminus 1 0.0096 6 25.90 193 256
ENTH ENTH domain 0.0093 6 20.80 194 215
V-ATPase_H_C V-ATPase subunit H 0.00016 12 20.80 200 255
EF1_GNE EF-1 guanine nucleotide exchange domain 0.18 2 20.80 221 247
RTP1_C1 Required for nuclear transport of RNA pol II C-terminus 1 0.059 3 25.90 231 267
Arm Armadillo/beta-catenin-like repeat 0.041 4 20.60 232 253
HEAT_EZ HEAT-like repeat 0.24 2 27.00 239 249
HEAT HEAT repeat 0.0058 7 23.50 239 255
ENTH ENTH domain 0.25 1 20.80 269 296

324

Fes1
V-ATPase_H_C
GP67
ENTH
MMS19_N
SIL1
EF1_GNE
MOR2-PAG1_C
V-ATPase_H_C
Arm
HEAT
MMS19_N
ENTH
HEAT_EZ
Atx10homo_assoc
Arm
HEAT
RTP1_C1
RTP1_C1
MMS19_N
MOR2-PAG1_C
RTP1_C1
ENTH
V-ATPase_H_C
EF1_GNE
RTP1_C1
Arm
HEAT_EZ
HEAT
ENTH

References:

V-ATPase_H_C
10954728 Regulation of yeast ectoapyrase ynd1p activity by activator subunit Vma13p of vacuolar H+-ATPase. J Biol Chem 2000;275:35592-35599.
18708638 Functional characterization of the N-terminal domain of subunit H (Vma13p) of the yeast vacuolar ATPase. J Biol Chem. 2008; [Epub ahead of print]
16141210 Structural and functional separation of the N- and C-terminal domains of the yeast V-ATPase subunit H. J Biol Chem. 2005;280:36978-36985.

Fes1
12052876 Nucleotide exchange factor for the yeast Hsp70 molecular chaperone Ssa1p. Mol Cell Biol. 2002;22:4677-4689.

HEAT_EZ

Arm
9298899 Three-dimensional structure of the armadillo repeat region of beta-catenin. Cell 1997;90:871-882.
8573337 Signal transduction of beta-catenin. Curr Opin Cell Biol 1995;7:634-640.
9309175 Armadillo and dTCF: a marriage made in the nucleus. Curr Opin Genet Dev 1997;7:459-466.
8259519 Association of the APC tumor suppressor protein with catenins. Science 1993;262:1734-1737.
8259518 Association of the APC gene product with beta-catenin. Science 1993;262:1731-1734.
2261639 The segment polarity gene armadillo encodes a functionally modular protein that is the Drosophila homolog of human plakoglobin. Cell 1990;63:1167-1176.

MOR2-PAG1_C

Atx10homo_assoc
15201271 Ataxin-10, the spinocerebellar ataxia type 10 neurodegenerative disorder protein, is essential for survival of cerebellar neurons. J Biol Chem. 2004;279:35542-35550.

MMS19_N
11328871 Cloning the human and mouse MMS19 genes and functional complementation of a yeast mms19 deletion mutant. Nucleic Acids Res. 2001;29:1884-1891.

HEAT
7550332 HEAT repeats in the Huntington's disease protein. Nat Genet 1995;11:115-116.
9989501 The structure of the protein phosphatase 2A PR65/A subunit reveals the conformation of its 15 tandemly repeated HEAT motifs. Cell 1999;96:99-110.

GP67

SIL1

ENTH
10048338 Identification of a novel domain shared by putative components of the endocytic and cytoskeletal machinery. Protein Sci 1999;8:435-438.

EF1_GNE
10368288 The solution structure of the guanine nucleotide exchange domain of human elongation factor 1beta reveals a striking resemblance to that of EF-Ts from Escherichia coli. Structure Fold Des 1999;7:217-226.

RTP1_C1

Domain	Description	Evalue	Bits	GA	Start	End
Fes1	Nucleotide exchange factor Fes1	1.1E-11	35	21.40	10	95
V-ATPase_H_C	V-ATPase subunit H	5.2E-05	13	20.80	10	129
GP67	Gene product 67	0.00022	12	27.00	33	52
ENTH	ENTH domain	0.94	-1	20.80	36	62
MMS19_N	NER and RNAPII transcription protein n terminal	1	-1	21.40	54	87
SIL1	Nucleotide exchange factor SIL1	6E-08	22	35.50	62	218
EF1_GNE	EF-1 guanine nucleotide exchange domain	0.0027	8	20.80	69	93
MOR2-PAG1_C	Cell morphogenesis C-terminal	0.033	4	25.00	96	151
V-ATPase_H_C	V-ATPase subunit H	0.00014	12	20.80	98	172
Arm	Armadillo/beta-catenin-like repeat	0.8	0	20.60	99	123
HEAT	HEAT repeat	0.033	5	23.50	104	128
MMS19_N	NER and RNAPII transcription protein n terminal	0.0012	8	21.40	106	173
ENTH	ENTH domain	0.57	0	20.80	109	126
HEAT_EZ	HEAT-like repeat	0.001	10	27.00	115	169
Atx10homo_assoc	Spinocerebellar ataxia type 10 protein domain	0.00026	11	22.40	119	174
Arm	Armadillo/beta-catenin-like repeat	0.028	5	20.60	146	169
HEAT	HEAT repeat	0.032	5	23.50	146	170
RTP1_C1	Required for nuclear transport of RNA pol II C-terminus 1	0.09	3	25.90	151	173
RTP1_C1	Required for nuclear transport of RNA pol II C-terminus 1	0.0062	7	25.90	151	217
MMS19_N	NER and RNAPII transcription protein n terminal	0.002	7	21.40	189	275
MOR2-PAG1_C	Cell morphogenesis C-terminal	0.0003	11	25.00	193	250
RTP1_C1	Required for nuclear transport of RNA pol II C-terminus 1	0.0096	6	25.90	193	256
ENTH	ENTH domain	0.0093	6	20.80	194	215
V-ATPase_H_C	V-ATPase subunit H	0.00016	12	20.80	200	255
EF1_GNE	EF-1 guanine nucleotide exchange domain	0.18	2	20.80	221	247
RTP1_C1	Required for nuclear transport of RNA pol II C-terminus 1	0.059	3	25.90	231	267
Arm	Armadillo/beta-catenin-like repeat	0.041	4	20.60	232	253
HEAT_EZ	HEAT-like repeat	0.24	2	27.00	239	249
HEAT	HEAT repeat	0.0058	7	23.50	239	255
ENTH	ENTH domain	0.25	1	20.80	269	296