c2pfam

AT1G22740.1 :

Domain Description Evalue Bits GA Start End
MCM MCM2/3/5 family 0.00015 12 25.20 4 37
DAP3 Mitochondrial ribosomal death-associated protein 3 0.00033 11 23.10 6 34
Arf ADP-ribosylation factor family 2.3E-15 47 20.30 8 161
GTP_EFTU Elongation factor Tu GTP binding domain 0.056 4 20.20 9 29
Septin Septin 1.7E-05 15 20.00 9 55
TniB Bacterial TniB protein 0.00013 12 20.10 9 36
AAA_24 AAA domain 4.9E-05 14 27.00 9 30
SRPRB Signal recognition particle receptor beta subunit 5.5E-05 13 20.50 10 71
NTPase_1 NTPase 6.3E-05 14 23.90 10 70
NB-ARC NB-ARC domain 0.00019 11 23.50 10 38
AAA_7 P-loop containing dynein motor region 2.3E-05 15 25.80 10 39
PduV-EutP Ethanolamine utilisation - propanediol utilisation 0.00011 13 20.50 10 47
AAA_16 AAA ATPase domain 1.9E-05 16 32.60 10 36
MMR_HSR1 GTPase of unknown function 1.8E-10 32 24.50 10 108
Gtr1_RagA Gtr1/RagA G protein conserved region 1.3E-08 25 20.10 10 129
Ras Ras family 0 185 20.80 10 175
Roc Ras of Complex, Roc, domain of DAPkinase 1.8E-36 116 27.00 10 128
RsgA_GTPase RsgA GTPase 4.2E-06 18 30.00 11 32
cobW CobW/HypB/UreG, nucleotide-binding domain 2.7E-06 18 20.70 11 90
AAA_22 AAA domain 1.5E-05 16 27.00 11 52
NACHT NACHT domain 0.00023 12 20.40 11 28
AAA_5 AAA domain (dynein-related subfamily) 0.0007 10 20.80 11 29
AAA_14 AAA domain 0.0004 11 27.00 11 50
ATPase_2 ATPase domain predominantly from Archaea 4.2E-05 14 33.20 11 37
ATP_bind_1 Conserved hypothetical ATP binding protein 0.067 4 20.20 13 30
ATP_bind_1 Conserved hypothetical ATP binding protein 7.4E-05 13 20.20 41 160
GTP_EFTU Elongation factor Tu GTP binding domain 2.2E-05 15 20.20 54 145
cobW CobW/HypB/UreG, nucleotide-binding domain 0.65 0 20.70 81 129
PduV-EutP Ethanolamine utilisation - propanediol utilisation 0.93 0 20.50 140 170

203

MCM
DAP3
Arf
GTP_EFTU
Septin
TniB
AAA_24
SRPRB
NTPase_1
NB-ARC
AAA_7
PduV-EutP
AAA_16
MMR_HSR1
Gtr1_RagA
Ras
Roc
RsgA_GTPase
cobW
AAA_22
NACHT
AAA_5
AAA_14
ATPase_2
ATP_bind_1
ATP_bind_1
GTP_EFTU
cobW
PduV-EutP

References:

SRPRB
7844142 The beta subunit of the signal recognition particle receptor is a transmembrane GTPase that anchors the alpha subunit, a peripheral membrane GTPase, to the endoplasmic reticulum membrane. J Cell Biol. 1995;128:273-282.

AAA_16

GTP_EFTU
9311785 Visualization of elongation factor Tu on the Escherichia coli ribosome. Nature 1997;389:403-406.

AAA_14

NB-ARC
9545207 The NB-ARC domain: a novel signalling motif shared by plant resistance gene products and regulators of cell death in animals. Curr Biol 1998;8:226-227.

Septin
12665577 Molecular dissection of a yeast septin: distinct domains are required for septin interaction, localization, and function. Mol Cell Biol 2003;23:2762-2777.
14611653 The septins. Genome Biol 2003;4:236.

RsgA_GTPase

AAA_5
7646486 A 200-amino acid ATPase module in search of a basic function. Bioessays 1995;17:639-650.
9927482 AAA+: A class of chaperone-like ATPases associated with the assembly, operation, and disassembly of protein complexes. Genome Res 1999;9:27-43.

DAP3
9889192 Structure-function analysis of an evolutionary conserved protein, DAP3, which mediates TNF-alpha- and Fas-induced cell death. EMBO J. 1999;18:353-362.
11017876 The apoptosis mediator mDAP-3 is a novel member of a conserved family of mitochondrial proteins. J Cell Sci. 2000;113:3603-3612.

MCM
8332451 A common set of conserved motifs in a vast variety of putative nucleic acid-dependent ATPases including MCM proteins involved in the initiation of eukaryotic DNA replication. Nucleic Acids Res 1993;21:2541-2547.

AAA_7

NTPase_1

MMR_HSR1
8180467 Structure and evolution of a member of a new subfamily of GTP-binding proteins mapping to the human MHC class I region. Mamm Genome 1994;5:100-105.

Arf
7990966 Structure of the human ADP-ribosylation factor 1 complexed with GDP. Nature 1994;372:704-708.
7759471 Structure and function of ARF proteins: Activators of cholera toxin and critical components of intracellular vesicular transport processes. J. Biol. Chem. 1995;270:12327-12330.
7770914 Arf proteins: the membrane traffic police? Trends Biochem Sci 1995;20:147-150.
1899243 Human ADP-ribosylation factors. A functionally conserved family of GTP-binding proteins. J Biol Chem 1991;266:2606-2614.

ATPase_2

NACHT
10782090 The NACHT family - a new group of predicted NTPases implicated in apoptosis and MHC transcription activation. Trends Biochem Sci 2000;25:223-224.

TniB
8195081 Transposon Tn5090 of plasmid R751, which carries an integron, is related to Tn7, Mu, and the retroelements. J Bacteriol 1994;176:3257-3268.
8594337 Four genes, two ends, and a res region are involved in transposition of Tn5053: a paradigm for a novel family of transposons carrying either a mer operon or an integron. Mol Microbiol 1995;17:1189-1200.

Ras
11387043 The Rab GTPase family. Genome Biol 2001;2:REVIEWS3007.

cobW
9140970 The HypB protein from Bradyrhizobium japonicum can store nickel and is required for the nickel-dependent transcriptional regulation of hydrogenase. Mol Microbiol 1997;24:119-128.
9209019 Characterization of UreG, identification of a UreD-UreF-UreG complex, and evidence suggesting that a nucleotide-binding site in UreG is required for in vivo metallocenter assembly of Klebsiella aerogenes urease. J Bacteriol 1997;179:4081-4086.
8423137 The product of the hypB gene, which is required for nickel incorporation into hydrogenases, is a novel guanine nucleotide-binding protein. J Bacteriol 1993;175:630-635.
1624427 Klebsiella aerogenes urease gene cluster: sequence of ureD and demonstration that four accessory genes (ureD, ureE, ureF, and ureG) are involved in nickel metallocenter biosynthesis. J Bacteriol 1992;174:4324-4330.
1655697 Nucleotide sequence and genetic analysis of a 13.1-kilobase-pair Pseudomonas denitrificans DNA fragment containing five cob genes and identification of structural genes encoding Cob(I)alamin adenosyltransferase, cobyric acid synthase, and bifunctional cob J Bacteriol 1991;173:6074-6087.

ATP_bind_1

Gtr1_RagA
1620108 Putative GTP-binding protein, Gtr1, associated with the function of the Pho84 inorganic phosphate transporter in Saccharomyces cerevisiae. Mol Cell Biol 1992;12:2958-2966.
7499430 Cloning of a novel family of mammalian GTP-binding proteins (RagA, RagBs, RagB1) with remote similarity to the Ras-related GTPases. J Biol Chem 1995;270:28982-28988.
10388807 Saccharomyces cerevisiae putative G protein, Gtr1p, which forms complexes with itself and a novel protein designated as Gtr2p, negatively regulates the Ran/Gsp1p G protein cycle through Gtr2p. Genetics 1999;152:853-867.
11073942 Novel G proteins, Rag C and Rag D, interact with GTP-binding proteins, Rag A and Rag B. J Biol Chem 2001;276:7246-7257.

AAA_24

AAA_22

Roc

PduV-EutP
15516577 Evidence that a B12-adenosyl transferase is encoded within the ethanolamine operon of Salmonella enterica. J Bacteriol. 2004;186:7635-7644.
10464203 The 17-gene ethanolamine (eut) operon of Salmonella typhimurium encodes five homologues of carboxysome shell proteins. J Bacteriol 1999;181:5317-5329.
10498708 The propanediol utilization (pdu) operon of Salmonella enterica serovar Typhimurium LT2 includes genes necessary for formation of polyhedral organelles involved in coenzyme B(12)-dependent 1, 2-propanediol degradation. J Bacteriol. 1999;181:5967-5975.

Domain	Description	Evalue	Bits	GA	Start	End
MCM	MCM2/3/5 family	0.00015	12	25.20	4	37
DAP3	Mitochondrial ribosomal death-associated protein 3	0.00033	11	23.10	6	34
Arf	ADP-ribosylation factor family	2.3E-15	47	20.30	8	161
GTP_EFTU	Elongation factor Tu GTP binding domain	0.056	4	20.20	9	29
Septin	Septin	1.7E-05	15	20.00	9	55
TniB	Bacterial TniB protein	0.00013	12	20.10	9	36
AAA_24	AAA domain	4.9E-05	14	27.00	9	30
SRPRB	Signal recognition particle receptor beta subunit	5.5E-05	13	20.50	10	71
NTPase_1	NTPase	6.3E-05	14	23.90	10	70
NB-ARC	NB-ARC domain	0.00019	11	23.50	10	38
AAA_7	P-loop containing dynein motor region	2.3E-05	15	25.80	10	39
PduV-EutP	Ethanolamine utilisation - propanediol utilisation	0.00011	13	20.50	10	47
AAA_16	AAA ATPase domain	1.9E-05	16	32.60	10	36
MMR_HSR1	GTPase of unknown function	1.8E-10	32	24.50	10	108
Gtr1_RagA	Gtr1/RagA G protein conserved region	1.3E-08	25	20.10	10	129
Ras	Ras family	0	185	20.80	10	175
Roc	Ras of Complex, Roc, domain of DAPkinase	1.8E-36	116	27.00	10	128
RsgA_GTPase	RsgA GTPase	4.2E-06	18	30.00	11	32
cobW	CobW/HypB/UreG, nucleotide-binding domain	2.7E-06	18	20.70	11	90
AAA_22	AAA domain	1.5E-05	16	27.00	11	52
NACHT	NACHT domain	0.00023	12	20.40	11	28
AAA_5	AAA domain (dynein-related subfamily)	0.0007	10	20.80	11	29
AAA_14	AAA domain	0.0004	11	27.00	11	50
ATPase_2	ATPase domain predominantly from Archaea	4.2E-05	14	33.20	11	37
ATP_bind_1	Conserved hypothetical ATP binding protein	0.067	4	20.20	13	30
ATP_bind_1	Conserved hypothetical ATP binding protein	7.4E-05	13	20.20	41	160
GTP_EFTU	Elongation factor Tu GTP binding domain	2.2E-05	15	20.20	54	145
cobW	CobW/HypB/UreG, nucleotide-binding domain	0.65	0	20.70	81	129
PduV-EutP	Ethanolamine utilisation - propanediol utilisation	0.93	0	20.50	140	170