c2pfam

AT5G14800.1 :

Domain Description Evalue Bits GA Start End
Shikimate_DH Shikimate / quinate 5-dehydrogenase 7.9E-07 19 24.30 10 102
GFO_IDH_MocA Oxidoreductase family, NAD-binding Rossmann fold 2.9E-06 18 23.60 11 81
2-Hacid_dh_C D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3.3E-05 13 25.10 11 82
F420_oxidored NADP oxidoreductase coenzyme F420-dependent 9.3E-26 80 21.60 12 107
NAD_binding_2 NAD binding domain of 6-phosphogluconate dehydrogenase 2.2E-09 27 21.00 12 104
DapB_N Dihydrodipicolinate reductase, N-terminus 3.5E-06 17 20.80 12 108
3HCDH_N 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 0.011 5 20.90 12 33
PDH Prephenate dehydrogenase 2.8E-05 13 24.30 61 109
3HCDH_N 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 0.00075 9 20.90 62 133
NAD_Gly3P_dh_N NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 6.3E-07 19 23.10 63 114
ApbA Ketopantoate reductase PanE/ApbA 1.6E-05 14 21.70 63 110
P5CR_dimer Pyrroline-5-carboxylate reductase dimerisation 0 143 25.00 169 273

276

Shikimate_DH
GFO_IDH_MocA
2-Hacid_dh_C
F420_oxidored
NAD_binding_2
DapB_N
3HCDH_N
PDH
3HCDH_N
NAD_Gly3P_dh_N
ApbA
P5CR_dimer

References:

PDH

NAD_binding_2

DapB_N
8873595 Interaction of pyridine nucleotide substrates with Escherichia coli dihydrodipicolinate reductase: thermodynamic and structural analysis of binary complexes. Biochemistry 1996;35:13294-13302.
9398235 Three-dimensional structure of Escherichia coli dihydrodipicolinate reductase in complex with NADH and the inhibitor 2,6-pyridinedicarboxylate. Biochemistry 1997;36:15081-15088.
7893645 Three-dimensional structure of Escherichia coli dihydrodipicolinate reductase. Biochemistry 1995;34:3502-3512.

Shikimate_DH
7556173 The molecular biology of multidomain proteins. Selected examples. Eur J Biochem 1995;232:7-18.

F420_oxidored

NAD_Gly3P_dh_N
12032156 Kinetic regulation of the mitochondrial glycerol-3-phosphate dehydrogenase by the external NADH dehydrogenase in Saccharomyces cerevisiae. J Biol Chem 2002;277:27991-27995.
10801498 A potential target enzyme for trypanocidal drugs revealed by the crystal structure of NAD-dependent glycerol-3-phosphate dehydrogenase from Leishmania mexicana. Structure Fold Des 2000;8:541-552.

3HCDH_N
3479790 Structure of L-3-hydroxyacyl-coenzyme A dehydrogenase: preliminary chain tracing at 2.8-A resolution. Proc Natl Acad Sci U S A 1987;84:8262-8266.

2-Hacid_dh_C
9126843 Crystal structure of a ternary complex of D-2-hydroxyisocaproate dehydrogenase from Lactobacillus casei, NAD+ and 2-oxoisocaproate at 1.9 A resolution. J Mol Biol 1997;267:640-660.

GFO_IDH_MocA
8994968 The structure of glucose-fructose oxidoreductase from Zymomonas mobilis: an osmoprotective periplasmic enzyme containing non-dissociable NADP. Structure 1996;4:1413-1428.

P5CR_dimer

ApbA
9488683 ApbA, the ketopantoate reductase enzyme of Salmonella typhimurium is required for the synthesis of thiamine via the alternative pyrimidine biosynthetic pathway. J Biol Chem 1998;273:5572-5576.
9721324 The panE gene, encoding ketopantoate reductase, maps at 10 minutes and is allelic to apbA in Salmonella typhimurium. J Bacteriol 1998;180:4757-4759.

Domain	Description	Evalue	Bits	GA	Start	End
Shikimate_DH	Shikimate / quinate 5-dehydrogenase	7.9E-07	19	24.30	10	102
GFO_IDH_MocA	Oxidoreductase family, NAD-binding Rossmann fold	2.9E-06	18	23.60	11	81
2-Hacid_dh_C	D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain	3.3E-05	13	25.10	11	82
F420_oxidored	NADP oxidoreductase coenzyme F420-dependent	9.3E-26	80	21.60	12	107
NAD_binding_2	NAD binding domain of 6-phosphogluconate dehydrogenase	2.2E-09	27	21.00	12	104
DapB_N	Dihydrodipicolinate reductase, N-terminus	3.5E-06	17	20.80	12	108
3HCDH_N	3-hydroxyacyl-CoA dehydrogenase, NAD binding domain	0.011	5	20.90	12	33
PDH	Prephenate dehydrogenase	2.8E-05	13	24.30	61	109
3HCDH_N	3-hydroxyacyl-CoA dehydrogenase, NAD binding domain	0.00075	9	20.90	62	133
NAD_Gly3P_dh_N	NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus	6.3E-07	19	23.10	63	114
ApbA	Ketopantoate reductase PanE/ApbA	1.6E-05	14	21.70	63	110
P5CR_dimer	Pyrroline-5-carboxylate reductase dimerisation	0	143	25.00	169	273