c2pfam

AT5G16030.1 :

Domain Description Evalue Bits GA Start End
Nucleo_P87 Nucleopolyhedrovirus capsid protein P87 0.006 7 25.00 143 299
DUF4604 Domain of unknown function (DUF4604) 0.00028 13 27.50 202 307
PBP_sp32 Proacrosin binding protein sp32 0.013 6 20.70 215 301
DUF4746 Domain of unknown function (DUF4746) 5.3E-05 14 27.00 219 303
Roughex Drosophila roughex protein 0.0051 7 25.00 220 303
Sporozoite_P67 Sporozoite P67 surface antigen 0.0066 6 26.10 225 296
RR_TM4-6 Ryanodine Receptor TM 4-6 2.6E-05 15 25.10 230 305
PAXIP1_C PAXIP1-associated-protein-1 C term PTIP binding protein 3.8E-05 15 27.00 239 323
WD40_2 WD40 repeated domain 0.02 4 22.50 239 295
CDC27 DNA polymerase subunit Cdc27 0.00054 11 24.40 244 306
DNA_pol_phi DNA polymerase phi 0.00022 11 19.50 245 304
Nop14 Nop14-like family 5.1E-07 19 34.90 245 305
RRN3 RNA polymerase I specific transcription initiation factor RRN3 0.003 7 20.60 245 303
Autophagy_act_C Autophagocytosis associated protein, active-site domain 4.9E-05 15 21.30 247 298
Merozoite_SPAM Merozoite surface protein (SPAM) 0.00016 13 24.30 249 305
DUF4820 Domain of unknown function (DUF4820) 0.027 5 27.00 249 299
TRAP_alpha Translocon-associated protein (TRAP), alpha subunit 0.021 5 23.10 250 298
RNA_polI_A34 DNA-directed RNA polymerase I subunit RPA34.5 0.0076 8 21.40 250 305
Paf1 Paf1 0.013 5 20.40 250 303
Mpp10 Mpp10 protein 0.00018 11 21.40 250 324
SDA1 SDA1 6.6E-05 14 22.80 251 304
Vfa1 AAA-ATPase Vps4-associated protein 1 0.006 8 24.20 251 302
CobT Cobalamin biosynthesis protein CobT 0.0037 8 23.00 252 302
CDC45 CDC45-like protein 0.003 7 26.70 254 306
CPSF100_C Cleavage and polyadenylation factor 2 C-terminal 0.011 7 23.60 254 302
DUF913 Domain of Unknown Function (DUF913) 0.014 5 24.70 255 300
Presenilin Presenilin 0.013 5 23.60 255 301
Afi1 Docking domain of Afi1 for Arf3 in vesicle trafficking 0.016 7 25.50 256 299
Tim54 Inner membrane protein import complex subunit Tim54 0.00018 11 24.40 256 309
SpoIIP Stage II sporulation protein P (SpoIIP) 0.0033 8 20.10 257 304
CLN3 CLN3 protein 0.0057 7 19.30 258 331
HSP90 Hsp90 protein 0.02 5 20.60 259 304
Connexin Connexin 0.0064 7 20.60 264 331

339

Nucleo_P87
DUF4604
PBP_sp32
DUF4746
Roughex
Sporozoite_P67
RR_TM4-6
PAXIP1_C
WD40_2
CDC27
DNA_pol_phi
Nop14
RRN3
Autophagy_act_C
Merozoite_SPAM
DUF4820
TRAP_alpha
RNA_polI_A34
Paf1
Mpp10
SDA1
Vfa1
CobT
CDC45
CPSF100_C
DUF913
Presenilin
Afi1
Tim54
SpoIIP
CLN3
HSP90
Connexin

References:

HSP90
9187656 A molecular clamp in the crystal structure of the N-terminal domain of the yeast Hsp90 chaperone. Nat Struct Biol 1997;4:477-482.

RR_TM4-6

Nucleo_P87
2184573 A capsid-associated protein of the multicapsid nuclear polyhedrosis virus of Orgyia pseudotsugata: genetic location, sequence, transcriptional mapping, and immunocytochemical characterization. Virology 1990;176:133-144.

RRN3
8670901 RRN3 gene of Saccharomyces cerevisiae encodes an essential RNA polymerase I transcription factor which interacts with the polymerase independently of DNA template. EMBO J 1996;15:3964-3973.

DNA_pol_phi
12093911 The fifth essential DNA polymerase phi in Saccharomyces cerevisiae is localized to the nucleolus and plays an important role in synthesis of rRNA. Proc Natl Acad Sci U S A 2002;99:9133-9138.

TRAP_alpha
8050590 The N-terminal region of the alpha-subunit of the TRAP complex has a conserved cluster of negative charges. FEBS Lett 1994;349:324-326.

Nop14
11694595 Novel stress-responsive genes EMG1 and NOP14 encode conserved, interacting proteins required for 40S ribosome biogenesis. Mol Biol Cell 2001;12:3644-3657.

SDA1
10704371 The Saccharomyces cerevisiae SDA1 gene is required for actin cytoskeleton organization and cell cycle progression. J Cell Sci 2000;113:1199-1211.

CLN3
9490299 Molecular screening of Batten disease: identification of a missense mutation (E295K) in the CLN3 gene. Hum Genet 1998;102:57-62.

RNA_polI_A34
9121426 A34.5, a nonessential component of yeast RNA polymerase I, cooperates with subunit A14 and DNA topoisomerase I to produce a functional rRNA synthesis machine. Mol Cell Biol 1997;17:1787-1795.

Vfa1

DUF4746

Mpp10
9450966 M phase phosphoprotein 10 is a human U3 small nucleolar ribonucleoprotein component. Mol Biol Cell 1998;9:437-449.
12068309 A large nucleolar U3 ribonucleoprotein required for 18S ribosomal RNA biogenesis. Nature 2002;0:0-0.
9391061 Functional separation of pre-rRNA processing steps revealed by truncation of the U3 small nucleolar ribonucleoprotein component, Mpp10. Proc Natl Acad Sci U S A 1997;94:13536-13541.

PAXIP1_C

Presenilin
9384549 Presenilins and Alzheimer's disease. Curr Opin Neurobiol 1997;7:683-688.
9384549 Presenilins and Alzheimer's disease. Curr Opin Neurobiol 1997;7:683-688.
9437013 Interaction of presenilins with the filamin family of actin-binding proteins. J Neurosci 1998;18:914-922.
9790190 Destabilisation of beta-catenin by mutations in presenilin-1 potentiates neuronal apoptosis. Nature 1998;395:698-702.

Roughex
11027291 Roughex mediates G(1) arrest through a physical association with cyclin A. Mol Cell Biol 2000;20:8220-8229.
11231149 The cyclin-dependent kinase inhibitor Roughex is involved in mitotic exit in Drosophila. Curr Biol 2001;11:151-160.

Connexin

DUF4820

CDC45
9660782 The human homolog of Saccharomyces cerevisiae CDC45. J Biol Chem 1998;273:18205-18209.

Sporozoite_P67
10024569 Linear peptide specificity of bovine antibody responses to p67 of Theileria parva and sequence diversity of sporozoite-neutralizing epitopes: implications for a vaccine. Infect Immun 1999;67:1261-1266.

PBP_sp32
8144514 An acrosomal protein, sp32, in mammalian sperm is a binding protein specific for two proacrosins and an acrosin intermediate. J Biol Chem 1994;269:10133-10140.

DUF913

CDC27
15579205 Mapping and mutation of the conserved DNA polymerase interaction motif (DPIM) located in the C-terminal domain of fission yeast DNA polymerase delta subunit Cdc27. BMC Mol Biol. 2004;5:21.

WD40_2

Paf1
11927560 The Paf1 complex physically and functionally associates with transcription elongation factors in vivo. EMBO J 2002;21:1764-1774.
11884586 Ctr9, Rtf1, and Leo1 are components of the Paf1/RNA polymerase II complex. Mol Cell Biol 2002;22:1971-1980.

Merozoite_SPAM
7891748 Molecular variation in a novel polymorphic antigen associated with Plasmodium falciparum merozoites. Mol Biochem Parasitol 1994;68:53-67.
7893643 Solution structure of a polypeptide containing four heptad repeat units from a merozoite surface antigen of Plasmodium falciparum. Biochemistry 1995;34:3479-3491.

DUF4604

SpoIIP
10096082 A vital stain for studying membrane dynamics in bacteria: a novel mechanism controlling septation during Bacillus subtilis sporulation. Mol Microbiol. 1999;31:1149-1159.
17376078 Engulfment during sporulation in Bacillus subtilis is governed by a multi-protein complex containing tandemly acting autolysins. Mol Microbiol. 2007;64:139-152.
17824930 Dual localization pathways for the engulfment proteins during Bacillus subtilis sporulation. Mol Microbiol. 2007;65:1534-1546.

Tim54
9412462 The Tim54p-Tim22p complex mediates insertion of proteins into the mitochondrial inner membrane. J Cell Biol. 1997;139:1663-1675.

CobT
1917840 Genetic and sequence analyses of a Pseudomonas denitrificans DNA fragment containing two cob genes. J Bacteriol 1991;173:6058-6065.

Autophagy_act_C
9023185 AUT1, a gene essential for autophagocytosis in the yeast Saccharomyces cerevisiae. J Bacteriol 1997;179:1068-1076.
12482611 Mouse Apg10 as an Apg12-conjugating enzyme: analysis by the conjugation-mediated yeast two-hybrid method. FEBS Lett. 2002;532:450-454.
17565192 Crystallization and preliminary X-ray analysis of Atg10. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2007;63:443-445.

CPSF100_C

Afi1

Domain	Description	Evalue	Bits	GA	Start	End
Nucleo_P87	Nucleopolyhedrovirus capsid protein P87	0.006	7	25.00	143	299
DUF4604	Domain of unknown function (DUF4604)	0.00028	13	27.50	202	307
PBP_sp32	Proacrosin binding protein sp32	0.013	6	20.70	215	301
DUF4746	Domain of unknown function (DUF4746)	5.3E-05	14	27.00	219	303
Roughex	Drosophila roughex protein	0.0051	7	25.00	220	303
Sporozoite_P67	Sporozoite P67 surface antigen	0.0066	6	26.10	225	296
RR_TM4-6	Ryanodine Receptor TM 4-6	2.6E-05	15	25.10	230	305
PAXIP1_C	PAXIP1-associated-protein-1 C term PTIP binding protein	3.8E-05	15	27.00	239	323
WD40_2	WD40 repeated domain	0.02	4	22.50	239	295
CDC27	DNA polymerase subunit Cdc27	0.00054	11	24.40	244	306
DNA_pol_phi	DNA polymerase phi	0.00022	11	19.50	245	304
Nop14	Nop14-like family	5.1E-07	19	34.90	245	305
RRN3	RNA polymerase I specific transcription initiation factor RRN3	0.003	7	20.60	245	303
Autophagy_act_C	Autophagocytosis associated protein, active-site domain	4.9E-05	15	21.30	247	298
Merozoite_SPAM	Merozoite surface protein (SPAM)	0.00016	13	24.30	249	305
DUF4820	Domain of unknown function (DUF4820)	0.027	5	27.00	249	299
TRAP_alpha	Translocon-associated protein (TRAP), alpha subunit	0.021	5	23.10	250	298
RNA_polI_A34	DNA-directed RNA polymerase I subunit RPA34.5	0.0076	8	21.40	250	305
Paf1	Paf1	0.013	5	20.40	250	303
Mpp10	Mpp10 protein	0.00018	11	21.40	250	324
SDA1	SDA1	6.6E-05	14	22.80	251	304
Vfa1	AAA-ATPase Vps4-associated protein 1	0.006	8	24.20	251	302
CobT	Cobalamin biosynthesis protein CobT	0.0037	8	23.00	252	302
CDC45	CDC45-like protein	0.003	7	26.70	254	306
CPSF100_C	Cleavage and polyadenylation factor 2 C-terminal	0.011	7	23.60	254	302
DUF913	Domain of Unknown Function (DUF913)	0.014	5	24.70	255	300
Presenilin	Presenilin	0.013	5	23.60	255	301
Afi1	Docking domain of Afi1 for Arf3 in vesicle trafficking	0.016	7	25.50	256	299
Tim54	Inner membrane protein import complex subunit Tim54	0.00018	11	24.40	256	309
SpoIIP	Stage II sporulation protein P (SpoIIP)	0.0033	8	20.10	257	304
CLN3	CLN3 protein	0.0057	7	19.30	258	331
HSP90	Hsp90 protein	0.02	5	20.60	259	304
Connexin	Connexin	0.0064	7	20.60	264	331