c2pfam

AT5G18660.1 :

Domain Description Evalue Bits GA Start End
DapB_N Dihydrodipicolinate reductase, N-terminus 6E-05 13 20.80 84 138
RmlD_sub_bind RmlD substrate binding domain 3.7E-05 12 19.80 85 138
NmrA NmrA-like family 2.7E-18 56 20.60 86 326
Epimerase NAD dependent epimerase/dehydratase family 2.6E-12 36 20.60 86 207
adh_short short chain dehydrogenase 1.8E-07 20 20.50 86 164
KR KR domain 8E-07 19 22.60 86 155
Polysacc_synt_2 Polysaccharide biosynthesis protein 1.7E-06 17 20.20 86 246
GDP_Man_Dehyd GDP-mannose 4,6 dehydratase 4.6E-06 16 27.00 87 125
3Beta_HSD 3-beta hydroxysteroid dehydrogenase/isomerase family 1.1E-09 27 20.00 87 208
NAD_binding_4 Male sterility protein 2E-05 13 20.10 89 206
NAD_binding_10 NAD(P)H-binding 8.2E-25 77 27.20 90 293
NAD_binding_4 Male sterility protein 0.91 -2 20.10 221 246

417

DapB_N
RmlD_sub_bind
NmrA
Epimerase
adh_short
KR
Polysacc_synt_2
GDP_Man_Dehyd
3Beta_HSD
NAD_binding_4
NAD_binding_10
NAD_binding_4

References:

KR

DapB_N
8873595 Interaction of pyridine nucleotide substrates with Escherichia coli dihydrodipicolinate reductase: thermodynamic and structural analysis of binary complexes. Biochemistry 1996;35:13294-13302.
9398235 Three-dimensional structure of Escherichia coli dihydrodipicolinate reductase in complex with NADH and the inhibitor 2,6-pyridinedicarboxylate. Biochemistry 1997;36:15081-15088.
7893645 Three-dimensional structure of Escherichia coli dihydrodipicolinate reductase. Biochemistry 1995;34:3502-3512.

adh_short
9735295 The refined crystal structure of Drosophila lebanonensis alcohol dehydrogenase at 1.9 A resolution. J Mol Biol 1998;282:383-399.
10387002 Structure of tropinone reductase-II complexed with NADP+ and pseudotropine at 1.9 A resolution: implication for stereospecific substrate binding and catalysis. Biochemistry 1999;38:7630-7637.

GDP_Man_Dehyd

NAD_binding_4
9351246 The Arabidopsis MALE STERILITY 2 protein shares similarity with reductases in elongation/condensation complexes. Plant J 1997;12:615-623.

Polysacc_synt_2
7961465 Sequence analysis and molecular characterization of genes required for the biosynthesis of type 1 capsular polysaccharide in Staphylococcus aureus. J Bacteriol 1994;176:7005-7016.
9079898 Identification of additional genes required for O-antigen biosynthesis in Vibrio cholerae O1. J Bacteriol 1997;179:2147-2153.

Epimerase
9174344 Structural analysis of UDP-sugar binding to UDP-galactose 4-epimerase from Escherichia coli. Biochemistry 1997;36:6294-6304.

3Beta_HSD
1562516 Structure and tissue-specific expression of 3 beta-hydroxysteroid dehydrogenase/5-ene-4-ene isomerase genes in human and rat classical and peripheral steroidogenic tissues. J Steroid Biochem Mol Biol 1992;41:421-435.

NmrA
11726498 The structure of the negative transcriptional regulator NmrA reveals a structural superfamily which includes the short-chain dehydrogenase/reductases. EMBO J 2001;20:6619-6626.

NAD_binding_10

RmlD_sub_bind
12057193 Variation on a Theme of SDR. dTDP-6-Deoxy-L- lyxo-4-Hexulose Reductase (RmlD) Shows a New Mg(2+)-Dependent Dimerization Mode. Structure (Camb) 2002;10:773-786.
10802738 RmlC, the third enzyme of dTDP-L-rhamnose pathway, is a new class of epimerase. Nat Struct Biol 2000;7:398-402.

Domain	Description	Evalue	Bits	GA	Start	End
DapB_N	Dihydrodipicolinate reductase, N-terminus	6E-05	13	20.80	84	138
RmlD_sub_bind	RmlD substrate binding domain	3.7E-05	12	19.80	85	138
NmrA	NmrA-like family	2.7E-18	56	20.60	86	326
Epimerase	NAD dependent epimerase/dehydratase family	2.6E-12	36	20.60	86	207
adh_short	short chain dehydrogenase	1.8E-07	20	20.50	86	164
KR	KR domain	8E-07	19	22.60	86	155
Polysacc_synt_2	Polysaccharide biosynthesis protein	1.7E-06	17	20.20	86	246
GDP_Man_Dehyd	GDP-mannose 4,6 dehydratase	4.6E-06	16	27.00	87	125
3Beta_HSD	3-beta hydroxysteroid dehydrogenase/isomerase family	1.1E-09	27	20.00	87	208
NAD_binding_4	Male sterility protein	2E-05	13	20.10	89	206
NAD_binding_10	NAD(P)H-binding	8.2E-25	77	27.20	90	293
NAD_binding_4	Male sterility protein	0.91	-2	20.10	221	246