c2pfam

AT5G24760.1 :

Domain Description Evalue Bits GA Start End
ADH_N Alcohol dehydrogenase GroES-like domain 1.4E-25 78 21.00 42 164
AlaDh_PNT_C Alanine dehydrogenase/PNT, C-terminal domain 7.5E-07 18 20.30 192 243
2-Hacid_dh_C D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 4.4E-06 15 25.10 196 242
AdoHcyase_NAD S-adenosyl-L-homocysteine hydrolase, NAD binding domain 8.5E-05 12 21.00 196 241
UDPG_MGDP_dh_N UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 9.4E-06 14 20.50 200 238
TrkA_N TrkA-N domain 4.4E-07 19 21.70 200 246
ADH_zinc_N Zinc-binding dehydrogenase 3.5E-26 81 30.00 208 333

381

ADH_N
AlaDh_PNT_C
2-Hacid_dh_C
AdoHcyase_NAD
UDPG_MGDP_dh_N
TrkA_N
ADH_zinc_N

References:

UDPG_MGDP_dh_N
2470755 Purification and characterization of guanosine diphospho-D-mannose dehydrogenase. A key enzyme in the biosynthesis of alginate by Pseudomonas aeruginosa. J Biol Chem 1989;264:9380-9385.
9013585 Properties and kinetic analysis of UDP-glucose dehydrogenase from group A streptococci. Irreversible inhibition by UDP-chloroacetol. J Biol Chem 1997;272:3416-3422.

ADH_zinc_N

ADH_N
8804825 Structural classification of proteins: new superfamilies. Curr Opin Struct Biol 1996;6:386-394.
10556240 Conserved structural features and sequence patterns in the GroES fold family. Protein Eng 1999;12:815-818.

AlaDh_PNT_C
11354603 Lysine metabolism in higher plants. Amino Acids 2001;20:261-279.

2-Hacid_dh_C
9126843 Crystal structure of a ternary complex of D-2-hydroxyisocaproate dehydrogenase from Lactobacillus casei, NAD+ and 2-oxoisocaproate at 1.9 A resolution. J Mol Biol 1997;267:640-660.

AdoHcyase_NAD

TrkA_N
9478130 A novel family of predicted phosphoesterases includes Drosophila prune protein and bacterial RecJ exonuclease. Trends Biochem Sci 1998;23:17-19.
8412700 NAD+ binding to the Escherichia coli K(+)-uptake protein TrkA and sequence similarity between TrkA and domains of a family of dehydrogenases suggest a role for NAD+ in bacterial transport. Mol Microbiol 1993;9:533-543.
11292341 Regulatory potential, phyletic distribution and evolution of ancient, intracellular small-molecule-binding domains. J Mol Biol 2001;307:1271-1292.

Domain	Description	Evalue	Bits	GA	Start	End
ADH_N	Alcohol dehydrogenase GroES-like domain	1.4E-25	78	21.00	42	164
AlaDh_PNT_C	Alanine dehydrogenase/PNT, C-terminal domain	7.5E-07	18	20.30	192	243
2-Hacid_dh_C	D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain	4.4E-06	15	25.10	196	242
AdoHcyase_NAD	S-adenosyl-L-homocysteine hydrolase, NAD binding domain	8.5E-05	12	21.00	196	241
UDPG_MGDP_dh_N	UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain	9.4E-06	14	20.50	200	238
TrkA_N	TrkA-N domain	4.4E-07	19	21.70	200	246
ADH_zinc_N	Zinc-binding dehydrogenase	3.5E-26	81	30.00	208	333