c2pfam

AT1G25490.1 :

Domain Description Evalue Bits GA Start End
Ecm29 Proteasome stabiliser 0.2 0 20.70 5 60
HEAT_2 HEAT repeats 6.2E-07 20 27.70 12 110
RTP1_C1 Required for nuclear transport of RNA pol II C-terminus 1 0.006 7 25.90 12 75
HEAT HEAT repeat 0.064 4 23.50 49 76
HEAT_2 HEAT repeats 9.9E-05 13 27.70 58 120
CLASP_N CLASP N terminal 0.58 -1 27.00 83 120
Vac14_Fab1_bd Vacuolar 14 Fab1-binding region 0.54 1 22.10 84 122
Adaptin_N Adaptin N terminal region 8.8E-05 11 20.30 86 299
HEAT HEAT repeat 0.00016 12 23.50 87 115
HEAT_PBS PBS lyase HEAT-like repeat 0.19 3 20.90 102 115
HEAT_2 HEAT repeats 0.00061 10 27.70 163 192
HEAT HEAT repeat 6.8E-06 16 23.50 170 192
RTP1_C1 Required for nuclear transport of RNA pol II C-terminus 1 0.00048 10 25.90 170 273
Cnd1 non-SMC mitotic condensation complex subunit 1 0.0015 8 26.40 171 223
HEAT_EZ HEAT-like repeat 2.1E-05 15 27.00 177 223
Ecm29 Proteasome stabiliser 0.045 2 20.70 178 224
HEAT_PBS PBS lyase HEAT-like repeat 0.014 6 20.90 179 192
TAF6_C TAF6 C-terminal HEAT repeat domain 0.17 2 20.40 179 207
Vac14_Fab1_bd Vacuolar 14 Fab1-binding region 0.72 1 22.10 192 219
CLASP_N CLASP N terminal 3.4E-05 13 27.00 203 307
HEAT HEAT repeat 0.0052 7 23.50 203 231
HEAT_2 HEAT repeats 3.7E-08 24 27.70 209 301
HEAT_PBS PBS lyase HEAT-like repeat 0.37 2 20.90 218 249
HEAT_EZ HEAT-like repeat 0.24 2 27.00 226 262
Vac14_Fab1_bd Vacuolar 14 Fab1-binding region 2.8E-07 21 22.10 235 300
HEAT HEAT repeat 1.2E-07 22 23.50 242 270
IFRD Interferon-related developmental regulator (IFRD) 0.0046 6 25.00 243 301
HEAT_2 HEAT repeats 0.0008 10 27.70 268 301
Vac14_Fab1_bd Vacuolar 14 Fab1-binding region 0.0034 8 22.10 279 339
HEAT_EZ HEAT-like repeat 0.00011 13 27.00 279 302
HEAT HEAT repeat 2.3E-05 15 23.50 281 309
IFRD Interferon-related developmental regulator (IFRD) 0.02 4 25.00 281 301
Arm Armadillo/beta-catenin-like repeat 0.0061 7 20.60 282 302
HEAT_2 HEAT repeats 5.2E-06 17 27.70 286 360
Ecm29 Proteasome stabiliser 0.73 -2 20.70 294 343
Adaptin_N Adaptin N terminal region 9.2E-05 11 20.30 307 506
HEAT_EZ HEAT-like repeat 0.19 2 27.00 315 338
CLASP_N CLASP N terminal 0.49 0 27.00 316 341
Cnd1 non-SMC mitotic condensation complex subunit 1 0.0002 11 26.40 317 387
HEAT HEAT repeat 4.2E-05 14 23.50 320 349
Vac14_Fab1_bd Vacuolar 14 Fab1-binding region 0.23 2 22.10 339 414
HEAT_EZ HEAT-like repeat 0.16 3 27.00 342 376
RTP1_C1 Required for nuclear transport of RNA pol II C-terminus 1 0.029 4 25.90 352 407
Ecm29 Proteasome stabiliser 0.021 3 20.70 354 390
Arm Armadillo/beta-catenin-like repeat 0.035 4 20.60 359 377
HEAT HEAT repeat 1.9E-05 15 23.50 359 384
HEAT_2 HEAT repeats 2.9E-15 46 27.70 361 461
Vac14_Fab1_bd Vacuolar 14 Fab1-binding region 0.13 3 22.10 394 455
HEAT HEAT repeat 4E-05 14 23.50 398 426
CLASP_N CLASP N terminal 0.14 1 27.00 435 468
HEAT HEAT repeat 1.3E-06 18 23.50 440 465
IFRD Interferon-related developmental regulator (IFRD) 0.55 -1 25.00 441 507
RTP1_C1 Required for nuclear transport of RNA pol II C-terminus 1 0.045 4 25.90 442 555
TAF6_C TAF6 C-terminal HEAT repeat domain 0.00071 10 20.40 445 482
HEAT_EZ HEAT-like repeat 0.0088 7 27.00 452 482
HEAT HEAT repeat 0.002 8 23.50 476 505
HEAT_2 HEAT repeats 0.0035 8 27.70 478 539
Vac14_Fab1_bd Vacuolar 14 Fab1-binding region 0.001 10 22.10 508 574
CLASP_N CLASP N terminal 0.023 4 27.00 513 573
HEAT HEAT repeat 0.0037 8 23.50 515 544
Cnd1 non-SMC mitotic condensation complex subunit 1 0.015 5 26.40 519 581
HEAT_2 HEAT repeats 0.00011 12 27.70 528 587
HEAT HEAT repeat 0.0031 8 23.50 556 580
HEAT_EZ HEAT-like repeat 0.12 3 27.00 557 579

588

Ecm29
HEAT_2
RTP1_C1
HEAT
HEAT_2
CLASP_N
Vac14_Fab1_bd
Adaptin_N
HEAT
HEAT_PBS
HEAT_2
HEAT
RTP1_C1
Cnd1
HEAT_EZ
Ecm29
HEAT_PBS
TAF6_C
Vac14_Fab1_bd
CLASP_N
HEAT
HEAT_2
HEAT_PBS
HEAT_EZ
Vac14_Fab1_bd
HEAT
IFRD
HEAT_2
Vac14_Fab1_bd
HEAT_EZ
HEAT
IFRD
Arm
HEAT_2
Ecm29
Adaptin_N
HEAT_EZ
CLASP_N
Cnd1
HEAT
Vac14_Fab1_bd
HEAT_EZ
RTP1_C1
Ecm29
Arm
HEAT
HEAT_2
Vac14_Fab1_bd
HEAT
CLASP_N
HEAT
IFRD
RTP1_C1
TAF6_C
HEAT_EZ
HEAT
HEAT_2
Vac14_Fab1_bd
CLASP_N
HEAT
Cnd1
HEAT_2
HEAT
HEAT_EZ

References:

HEAT_PBS
8132596 Oligomeric structure, enzyme kinetics, and substrate specificity of the phycocyanin alpha subunit phycocyanobilin lyase. J Biol Chem 1994;269:8686-8694.
9023176 A role for cpeYZ in cyanobacterial phycoerythrin biosynthesis. J Bacteriol 1997;179:998-1006.
10708746 Novel activity of a phycobiliprotein lyase: both the attachment of phycocyanobilin and the isomerization to phycoviolobilin are catalyzed by the proteins PecE and PecF encoded by the phycoerythrocyanin operon. FEBS Lett 2000;469:9-13.
9882677 A polypeptide with similarity to phycocyanin alpha-subunit phycocyanobilin lyase involved in degradation of phycobilisomes. J Bacteriol 1999;181:610-617.

CLASP_N
16951255 S. pombe CLASP needs dynein, not EB1 or CLIP170, to induce microtubule instability and slows polymerization rates at cell tips in a dynein-dependent manner. Genes Dev. 2006;20:2421-2436.
16914514 Mammalian CLASP1 and CLASP2 cooperate to ensure mitotic fidelity by regulating spindle and kinetochore function. Mol Biol Cell. 2006;17:4526-4542.

Arm
9298899 Three-dimensional structure of the armadillo repeat region of beta-catenin. Cell 1997;90:871-882.
8573337 Signal transduction of beta-catenin. Curr Opin Cell Biol 1995;7:634-640.
9309175 Armadillo and dTCF: a marriage made in the nucleus. Curr Opin Genet Dev 1997;7:459-466.
8259519 Association of the APC tumor suppressor protein with catenins. Science 1993;262:1734-1737.
8259518 Association of the APC gene product with beta-catenin. Science 1993;262:1731-1734.
2261639 The segment polarity gene armadillo encodes a functionally modular protein that is the Drosophila homolog of human plakoglobin. Cell 1990;63:1167-1176.

Adaptin_N
9261055 Linking cargo to vesicle formation: receptor tail interactions with coat proteins. Curr Opin Cell Biol 1997;9:488-495.
2495531 Structural and functional division into two domains of the large (100- to 115-kDa)chains of the clathrin-associated protein complex AP-2. Proc Natl Acad Sci U S A 1989;86:2612-2616.

Vac14_Fab1_bd

IFRD
9050919 The human homolog of the rodent immediate early response genes, PC4 and TIS7, resides in the lung cancer tumor suppressor gene region on chromosome 3p21. Hum Genet 1997;99:334-341.
9722946 Cloning of the human interferon-related developmental regulator (IFRD1) gene coding for the PC4 protein, a member of a novel family of developmentally regulated genes. Genomics 1998;51:233-242.

HEAT
7550332 HEAT repeats in the Huntington's disease protein. Nat Genet 1995;11:115-116.
9989501 The structure of the protein phosphatase 2A PR65/A subunit reveals the conformation of its 15 tandemly repeated HEAT motifs. Cell 1999;96:99-110.

HEAT_EZ

Cnd1

Ecm29

TAF6_C

RTP1_C1

HEAT_2

Domain	Description	Evalue	Bits	GA	Start	End
Ecm29	Proteasome stabiliser	0.2	0	20.70	5	60
HEAT_2	HEAT repeats	6.2E-07	20	27.70	12	110
RTP1_C1	Required for nuclear transport of RNA pol II C-terminus 1	0.006	7	25.90	12	75
HEAT	HEAT repeat	0.064	4	23.50	49	76
HEAT_2	HEAT repeats	9.9E-05	13	27.70	58	120
CLASP_N	CLASP N terminal	0.58	-1	27.00	83	120
Vac14_Fab1_bd	Vacuolar 14 Fab1-binding region	0.54	1	22.10	84	122
Adaptin_N	Adaptin N terminal region	8.8E-05	11	20.30	86	299
HEAT	HEAT repeat	0.00016	12	23.50	87	115
HEAT_PBS	PBS lyase HEAT-like repeat	0.19	3	20.90	102	115
HEAT_2	HEAT repeats	0.00061	10	27.70	163	192
HEAT	HEAT repeat	6.8E-06	16	23.50	170	192
RTP1_C1	Required for nuclear transport of RNA pol II C-terminus 1	0.00048	10	25.90	170	273
Cnd1	non-SMC mitotic condensation complex subunit 1	0.0015	8	26.40	171	223
HEAT_EZ	HEAT-like repeat	2.1E-05	15	27.00	177	223
Ecm29	Proteasome stabiliser	0.045	2	20.70	178	224
HEAT_PBS	PBS lyase HEAT-like repeat	0.014	6	20.90	179	192
TAF6_C	TAF6 C-terminal HEAT repeat domain	0.17	2	20.40	179	207
Vac14_Fab1_bd	Vacuolar 14 Fab1-binding region	0.72	1	22.10	192	219
CLASP_N	CLASP N terminal	3.4E-05	13	27.00	203	307
HEAT	HEAT repeat	0.0052	7	23.50	203	231
HEAT_2	HEAT repeats	3.7E-08	24	27.70	209	301
HEAT_PBS	PBS lyase HEAT-like repeat	0.37	2	20.90	218	249
HEAT_EZ	HEAT-like repeat	0.24	2	27.00	226	262
Vac14_Fab1_bd	Vacuolar 14 Fab1-binding region	2.8E-07	21	22.10	235	300
HEAT	HEAT repeat	1.2E-07	22	23.50	242	270
IFRD	Interferon-related developmental regulator (IFRD)	0.0046	6	25.00	243	301
HEAT_2	HEAT repeats	0.0008	10	27.70	268	301
Vac14_Fab1_bd	Vacuolar 14 Fab1-binding region	0.0034	8	22.10	279	339
HEAT_EZ	HEAT-like repeat	0.00011	13	27.00	279	302
HEAT	HEAT repeat	2.3E-05	15	23.50	281	309
IFRD	Interferon-related developmental regulator (IFRD)	0.02	4	25.00	281	301
Arm	Armadillo/beta-catenin-like repeat	0.0061	7	20.60	282	302
HEAT_2	HEAT repeats	5.2E-06	17	27.70	286	360
Ecm29	Proteasome stabiliser	0.73	-2	20.70	294	343
Adaptin_N	Adaptin N terminal region	9.2E-05	11	20.30	307	506
HEAT_EZ	HEAT-like repeat	0.19	2	27.00	315	338
CLASP_N	CLASP N terminal	0.49	0	27.00	316	341
Cnd1	non-SMC mitotic condensation complex subunit 1	0.0002	11	26.40	317	387
HEAT	HEAT repeat	4.2E-05	14	23.50	320	349
Vac14_Fab1_bd	Vacuolar 14 Fab1-binding region	0.23	2	22.10	339	414
HEAT_EZ	HEAT-like repeat	0.16	3	27.00	342	376
RTP1_C1	Required for nuclear transport of RNA pol II C-terminus 1	0.029	4	25.90	352	407
Ecm29	Proteasome stabiliser	0.021	3	20.70	354	390
Arm	Armadillo/beta-catenin-like repeat	0.035	4	20.60	359	377
HEAT	HEAT repeat	1.9E-05	15	23.50	359	384
HEAT_2	HEAT repeats	2.9E-15	46	27.70	361	461
Vac14_Fab1_bd	Vacuolar 14 Fab1-binding region	0.13	3	22.10	394	455
HEAT	HEAT repeat	4E-05	14	23.50	398	426
CLASP_N	CLASP N terminal	0.14	1	27.00	435	468
HEAT	HEAT repeat	1.3E-06	18	23.50	440	465
IFRD	Interferon-related developmental regulator (IFRD)	0.55	-1	25.00	441	507
RTP1_C1	Required for nuclear transport of RNA pol II C-terminus 1	0.045	4	25.90	442	555
TAF6_C	TAF6 C-terminal HEAT repeat domain	0.00071	10	20.40	445	482
HEAT_EZ	HEAT-like repeat	0.0088	7	27.00	452	482
HEAT	HEAT repeat	0.002	8	23.50	476	505
HEAT_2	HEAT repeats	0.0035	8	27.70	478	539
Vac14_Fab1_bd	Vacuolar 14 Fab1-binding region	0.001	10	22.10	508	574
CLASP_N	CLASP N terminal	0.023	4	27.00	513	573
HEAT	HEAT repeat	0.0037	8	23.50	515	544
Cnd1	non-SMC mitotic condensation complex subunit 1	0.015	5	26.40	519	581
HEAT_2	HEAT repeats	0.00011	12	27.70	528	587
HEAT	HEAT repeat	0.0031	8	23.50	556	580
HEAT_EZ	HEAT-like repeat	0.12	3	27.00	557	579