c2pfam

AT5G44870.1 :

Domain Description Evalue Bits GA Start End
TIR TIR domain 3E-34 109 21.20 12 180
TIR_2 TIR domain 3.5E-15 47 28.00 14 108
AAA_23 AAA domain 0.12 3 27.00 79 174
NB-ARC NB-ARC domain 4.1E-23 72 23.50 262 491
AAA_23 AAA domain 0.013 6 27.00 267 294
MeaB Methylmalonyl Co-A mutase-associated GTPase MeaB 0.00013 12 23.10 267 300
ABC_tran ABC transporter 1.7E-05 16 23.10 270 303
AAA_14 AAA domain 6.3E-06 17 27.00 277 401
AAA_16 AAA ATPase domain 1.9E-05 16 32.60 277 306
NACHT NACHT domain 2.3E-06 18 20.40 278 367
AAA_24 AAA domain 0.00011 12 27.00 278 307
AAA_18 AAA domain 2.1E-05 16 29.40 279 329
MMR_HSR1 GTPase of unknown function 0.0006 10 24.50 279 299
NTPase_1 NTPase 0.00087 10 23.90 279 300
AAA ATPase family associated with various cellular activities (AAA) 0.00014 13 20.80 281 319
AAA_3 ATPase family associated with various cellular activities (AAA) 0.00016 12 21.10 281 312
AAA_33 AAA domain 0.00016 12 27.00 281 299
AAA_22 AAA domain 0.00037 11 27.00 281 343
LRR_5 BspA type Leucine rich repeat region (6 copies) 0.13 3 27.70 616 653
LRR_8 Leucine rich repeat 0.9 0 27.00 616 632
LRR_8 Leucine rich repeat 0.021 5 27.00 679 734
LRR_3 Leucine Rich Repeat 2.5E-09 27 20.20 679 698
LRR_4 Leucine Rich repeats (2 copies) 0.11 4 27.00 708 737
LRR_5 BspA type Leucine rich repeat region (6 copies) 0.00048 11 27.70 713 795
LRR_8 Leucine rich repeat 0.012 6 27.00 722 757
LRR_4 Leucine Rich repeats (2 copies) 0.035 5 27.00 749 788
LRR_3 Leucine Rich Repeat 0.38 1 20.20 750 756
LRR_8 Leucine rich repeat 0.0018 9 27.00 791 824
LRR_4 Leucine Rich repeats (2 copies) 1.1E-06 20 27.00 792 830
LRR_8 Leucine rich repeat 0.00097 10 27.00 825 874
LRR_4 Leucine Rich repeats (2 copies) 0.019 6 27.00 827 854
LRR_4 Leucine Rich repeats (2 copies) 0.00072 11 27.00 839 881
LRR_4 Leucine Rich repeats (2 copies) 0.011 7 27.00 862 893
LRR_4 Leucine Rich repeats (2 copies) 0.019 6 27.00 906 938

1170

TIR
TIR_2
AAA_23
NB-ARC
AAA_23
MeaB
ABC_tran
AAA_14
AAA_16
NACHT
AAA_24
AAA_18
MMR_HSR1
NTPase_1
AAA
AAA_3
AAA_33
AAA_22
LRR_5
LRR_8
LRR_8
LRR_3
LRR_4
LRR_5
LRR_8
LRR_4
LRR_3
LRR_8
LRR_4
LRR_8
LRR_4
LRR_4
LRR_4
LRR_4

References:

AAA_16

AAA_14

NB-ARC
9545207 The NB-ARC domain: a novel signalling motif shared by plant resistance gene products and regulators of cell death in animals. Curr Biol 1998;8:226-227.

AAA
7646486 A 200-amino acid ATPase module in search of a basic function. Bioessays 1995;17:639-650.
9927482 AAA+: A class of chaperone-like ATPases associated with the assembly, operation, and disassembly of protein complexes. Genome Res 1999;9:27-43.

LRR_3
7817399 The leucine-rich repeat: a versatile binding motif. Trends Biochem Sci 1994;19:415-421.
8264799 Crystal structure of porcine ribonuclease inhibitor, a protein with leucine-rich repeats. Nature 1993;366:751-756.

LRR_5

LRR_8

MeaB

NTPase_1

MMR_HSR1
8180467 Structure and evolution of a member of a new subfamily of GTP-binding proteins mapping to the human MHC class I region. Mamm Genome 1994;5:100-105.

AAA_33

NACHT
10782090 The NACHT family - a new group of predicted NTPases implicated in apoptosis and MHC transcription activation. Trends Biochem Sci 2000;25:223-224.

ABC_tran
1864505 Homology between proteins controlling Streptomyces fradiae tylosin resistance and ATP-binding transport. Gene 1991;102:27-32.
1977073 Structure and function of haemolysin B,P-glycoprotein and other members of a novel family of membrane translocators. Mol Microbiol 1990;4:873-880.
2229036 Binding protein-dependent transport systems. J Bioenerg Biomembr 1990;22:571-592.
9872322 Crystal structure of the ATP-binding subunit of an ABC transporter. Nature 1998;396:703-707.

TIR_2

AAA_3
7646486 A 200-amino acid ATPase module in search of a basic function. Bioessays 1995;17:639-650.
9927482 AAA+: A class of chaperone-like ATPases associated with the assembly, operation, and disassembly of protein complexes. Genome Res 1999;9:27-43.

TIR
9013863 The cloning and characterization of human MyD88: a member of an IL-1 receptor related family. FEBS Lett 1997;402:81-84.
9237759 A human homologue of the Drosophila Toll protein signals activation of adaptive immunity [see comments] Nature 1997;388:394-397.
12186654 Toll-like receptors: a family of pattern-recognition receptors in mammals. Genome Biol 2002;3:REVIEWS3011.

AAA_24

AAA_23

AAA_22

LRR_4

AAA_18

Domain	Description	Evalue	Bits	GA	Start	End
TIR	TIR domain	3E-34	109	21.20	12	180
TIR_2	TIR domain	3.5E-15	47	28.00	14	108
AAA_23	AAA domain	0.12	3	27.00	79	174
NB-ARC	NB-ARC domain	4.1E-23	72	23.50	262	491
AAA_23	AAA domain	0.013	6	27.00	267	294
MeaB	Methylmalonyl Co-A mutase-associated GTPase MeaB	0.00013	12	23.10	267	300
ABC_tran	ABC transporter	1.7E-05	16	23.10	270	303
AAA_14	AAA domain	6.3E-06	17	27.00	277	401
AAA_16	AAA ATPase domain	1.9E-05	16	32.60	277	306
NACHT	NACHT domain	2.3E-06	18	20.40	278	367
AAA_24	AAA domain	0.00011	12	27.00	278	307
AAA_18	AAA domain	2.1E-05	16	29.40	279	329
MMR_HSR1	GTPase of unknown function	0.0006	10	24.50	279	299
NTPase_1	NTPase	0.00087	10	23.90	279	300
AAA	ATPase family associated with various cellular activities (AAA)	0.00014	13	20.80	281	319
AAA_3	ATPase family associated with various cellular activities (AAA)	0.00016	12	21.10	281	312
AAA_33	AAA domain	0.00016	12	27.00	281	299
AAA_22	AAA domain	0.00037	11	27.00	281	343
LRR_5	BspA type Leucine rich repeat region (6 copies)	0.13	3	27.70	616	653
LRR_8	Leucine rich repeat	0.9	0	27.00	616	632
LRR_8	Leucine rich repeat	0.021	5	27.00	679	734
LRR_3	Leucine Rich Repeat	2.5E-09	27	20.20	679	698
LRR_4	Leucine Rich repeats (2 copies)	0.11	4	27.00	708	737
LRR_5	BspA type Leucine rich repeat region (6 copies)	0.00048	11	27.70	713	795
LRR_8	Leucine rich repeat	0.012	6	27.00	722	757
LRR_4	Leucine Rich repeats (2 copies)	0.035	5	27.00	749	788
LRR_3	Leucine Rich Repeat	0.38	1	20.20	750	756
LRR_8	Leucine rich repeat	0.0018	9	27.00	791	824
LRR_4	Leucine Rich repeats (2 copies)	1.1E-06	20	27.00	792	830
LRR_8	Leucine rich repeat	0.00097	10	27.00	825	874
LRR_4	Leucine Rich repeats (2 copies)	0.019	6	27.00	827	854
LRR_4	Leucine Rich repeats (2 copies)	0.00072	11	27.00	839	881
LRR_4	Leucine Rich repeats (2 copies)	0.011	7	27.00	862	893
LRR_4	Leucine Rich repeats (2 copies)	0.019	6	27.00	906	938