c2pfam

AT5G45060.1 :

Domain Description Evalue Bits GA Start End
TIR TIR domain 6.5E-37 117 21.20 14 180
TIR_2 TIR domain 2.9E-15 47 28.00 16 111
ATP_bind_1 Conserved hypothetical ATP binding protein 0.9 -1 20.20 131 199
ATPase_2 ATPase domain predominantly from Archaea 0.82 0 33.20 142 195
NB-ARC NB-ARC domain 4.6E-21 65 23.50 212 435
AAA_16 AAA ATPase domain 1.3E-08 26 32.60 213 298
ATPase_2 ATPase domain predominantly from Archaea 0.00063 10 33.20 213 259
AAA_30 AAA domain 0.00039 11 27.00 227 255
AAA_22 AAA domain 1.4E-05 16 27.00 228 321
MeaB Methylmalonyl Co-A mutase-associated GTPase MeaB 2.9E-05 13 23.10 229 261
ABC_tran ABC transporter 0.00066 11 23.10 229 253
AAA_14 AAA domain 2.3E-06 18 27.00 230 357
NACHT NACHT domain 2.8E-06 18 20.40 230 325
AAA_33 AAA domain 9E-05 13 27.00 231 252
AAA_24 AAA domain 0.00026 11 27.00 231 252
AAA_18 AAA domain 0.0001 13 29.40 232 253
ATP_bind_1 Conserved hypothetical ATP binding protein 0.00056 10 20.20 234 254
AAA ATPase family associated with various cellular activities (AAA) 0.0001 13 20.80 234 261
LRR_4 Leucine Rich repeats (2 copies) 0.05 5 27.00 561 591
LRR_8 Leucine rich repeat 0.00021 11 27.00 571 592
LRR_8 Leucine rich repeat 0.013 6 27.00 638 693
LRR_3 Leucine Rich Repeat 5E-11 33 20.20 638 657
LRR_8 Leucine rich repeat 0.13 3 27.00 683 714
LRR_4 Leucine Rich repeats (2 copies) 3E-05 15 27.00 683 719
LRR_4 Leucine Rich repeats (2 copies) 0.0068 7 27.00 727 764
LRR_8 Leucine rich repeat 5.7E-06 17 27.00 727 783
LRR_4 Leucine Rich repeats (2 copies) 0.01 7 27.00 747 793
LRR_4 Leucine Rich repeats (2 copies) 0.0066 7 27.00 796 824
LRR_8 Leucine rich repeat 0.0021 8 27.00 806 847
LRR_4 Leucine Rich repeats (2 copies) 0.0018 9 27.00 814 858
ATP_bind_1 Conserved hypothetical ATP binding protein 0.43 1 20.20 824 915
LRR_4 Leucine Rich repeats (2 copies) 0.085 4 27.00 839 871

1165

TIR
TIR_2
ATP_bind_1
ATPase_2
NB-ARC
AAA_16
ATPase_2
AAA_30
AAA_22
MeaB
ABC_tran
AAA_14
NACHT
AAA_33
AAA_24
AAA_18
ATP_bind_1
AAA
LRR_4
LRR_8
LRR_8
LRR_3
LRR_8
LRR_4
LRR_4
LRR_8
LRR_4
LRR_4
LRR_8
LRR_4
ATP_bind_1
LRR_4

References:

AAA_16

AAA_14

ABC_tran
1864505 Homology between proteins controlling Streptomyces fradiae tylosin resistance and ATP-binding transport. Gene 1991;102:27-32.
1977073 Structure and function of haemolysin B,P-glycoprotein and other members of a novel family of membrane translocators. Mol Microbiol 1990;4:873-880.
2229036 Binding protein-dependent transport systems. J Bioenerg Biomembr 1990;22:571-592.
9872322 Crystal structure of the ATP-binding subunit of an ABC transporter. Nature 1998;396:703-707.

AAA_33

AAA
7646486 A 200-amino acid ATPase module in search of a basic function. Bioessays 1995;17:639-650.
9927482 AAA+: A class of chaperone-like ATPases associated with the assembly, operation, and disassembly of protein complexes. Genome Res 1999;9:27-43.

LRR_3
7817399 The leucine-rich repeat: a versatile binding motif. Trends Biochem Sci 1994;19:415-421.
8264799 Crystal structure of porcine ribonuclease inhibitor, a protein with leucine-rich repeats. Nature 1993;366:751-756.

NB-ARC
9545207 The NB-ARC domain: a novel signalling motif shared by plant resistance gene products and regulators of cell death in animals. Curr Biol 1998;8:226-227.

LRR_8

MeaB

LRR_4

ATP_bind_1

ATPase_2

NACHT
10782090 The NACHT family - a new group of predicted NTPases implicated in apoptosis and MHC transcription activation. Trends Biochem Sci 2000;25:223-224.

AAA_30

TIR_2

AAA_24

TIR
9013863 The cloning and characterization of human MyD88: a member of an IL-1 receptor related family. FEBS Lett 1997;402:81-84.
9237759 A human homologue of the Drosophila Toll protein signals activation of adaptive immunity [see comments] Nature 1997;388:394-397.
12186654 Toll-like receptors: a family of pattern-recognition receptors in mammals. Genome Biol 2002;3:REVIEWS3011.

AAA_22

AAA_18

Domain	Description	Evalue	Bits	GA	Start	End
TIR	TIR domain	6.5E-37	117	21.20	14	180
TIR_2	TIR domain	2.9E-15	47	28.00	16	111
ATP_bind_1	Conserved hypothetical ATP binding protein	0.9	-1	20.20	131	199
ATPase_2	ATPase domain predominantly from Archaea	0.82	0	33.20	142	195
NB-ARC	NB-ARC domain	4.6E-21	65	23.50	212	435
AAA_16	AAA ATPase domain	1.3E-08	26	32.60	213	298
ATPase_2	ATPase domain predominantly from Archaea	0.00063	10	33.20	213	259
AAA_30	AAA domain	0.00039	11	27.00	227	255
AAA_22	AAA domain	1.4E-05	16	27.00	228	321
MeaB	Methylmalonyl Co-A mutase-associated GTPase MeaB	2.9E-05	13	23.10	229	261
ABC_tran	ABC transporter	0.00066	11	23.10	229	253
AAA_14	AAA domain	2.3E-06	18	27.00	230	357
NACHT	NACHT domain	2.8E-06	18	20.40	230	325
AAA_33	AAA domain	9E-05	13	27.00	231	252
AAA_24	AAA domain	0.00026	11	27.00	231	252
AAA_18	AAA domain	0.0001	13	29.40	232	253
ATP_bind_1	Conserved hypothetical ATP binding protein	0.00056	10	20.20	234	254
AAA	ATPase family associated with various cellular activities (AAA)	0.0001	13	20.80	234	261
LRR_4	Leucine Rich repeats (2 copies)	0.05	5	27.00	561	591
LRR_8	Leucine rich repeat	0.00021	11	27.00	571	592
LRR_8	Leucine rich repeat	0.013	6	27.00	638	693
LRR_3	Leucine Rich Repeat	5E-11	33	20.20	638	657
LRR_8	Leucine rich repeat	0.13	3	27.00	683	714
LRR_4	Leucine Rich repeats (2 copies)	3E-05	15	27.00	683	719
LRR_4	Leucine Rich repeats (2 copies)	0.0068	7	27.00	727	764
LRR_8	Leucine rich repeat	5.7E-06	17	27.00	727	783
LRR_4	Leucine Rich repeats (2 copies)	0.01	7	27.00	747	793
LRR_4	Leucine Rich repeats (2 copies)	0.0066	7	27.00	796	824
LRR_8	Leucine rich repeat	0.0021	8	27.00	806	847
LRR_4	Leucine Rich repeats (2 copies)	0.0018	9	27.00	814	858
ATP_bind_1	Conserved hypothetical ATP binding protein	0.43	1	20.20	824	915
LRR_4	Leucine Rich repeats (2 copies)	0.085	4	27.00	839	871