c2pfam

AT1G50700.1 :

Domain Description Evalue Bits GA Start End
Pkinase Protein kinase domain 0 254 20.40 73 331
PK_Tyr_Ser-Thr Protein tyrosine and serine/threonine kinase 3.7E-34 109 23.10 74 326
Kinase-like Kinase-like 0.5 0 25.00 79 130
APH Phosphotransferase enzyme family 0.022 5 22.40 87 161
Kdo Lipopolysaccharide kinase (Kdo/WaaP) family 2.6E-07 21 20.90 104 213
DUF4590 Domain of unknown function (DUF4590) 0.0022 8 27.00 114 149
DUF4590 Domain of unknown function (DUF4590) 0.23 2 27.00 170 226
Kinase-like Kinase-like 1.2E-06 18 25.00 171 319
APH Phosphotransferase enzyme family 0.0036 7 22.40 192 211
EF-hand_14 EF-hand domain 0.81 1 23.70 305 357
DUF2922 Protein of unknown function (DUF2922) 0.24 2 22.50 356 378
AbiJ_NTD4 AbiJ N-terminal domain 4 0.0001 13 34.00 361 481
SPARC_Ca_bdg Secreted protein acidic and rich in cysteine Ca binding region 0.00011 13 21.40 368 436
EF-hand_4 Cytoskeletal-regulatory complex EF hand 1.7E-05 15 21.30 371 438
EF-hand_7 EF-hand domain pair 8.2E-14 42 30.00 379 439
EF-hand_1 EF hand 3.5E-10 29 25.40 379 406
EF-hand_6 EF-hand domain 6.8E-08 23 25.00 379 407
EF-hand_5 EF hand 1.1E-07 22 25.90 379 401
EF-hand_8 EF-hand domain pair 1.9E-05 15 28.00 381 404
EF-hand_9 EF-hand domain 0.00044 11 37.00 381 438
EF-hand_11 EF-hand domain 0.0037 9 21.70 381 437
EF-hand_14 EF-hand domain 0.1 3 23.70 382 422
DUF2922 Protein of unknown function (DUF2922) 0.0023 8 22.50 390 420
EF-hand_8 EF-hand domain pair 6.2E-11 32 28.00 391 438
EFhand_Ca_insen Ca2+ insensitive EF hand 0.011 6 20.80 394 440
EF-hand_1 EF hand 5.9E-07 19 25.40 414 438
EF-hand_6 EF-hand domain 0.00076 10 25.00 416 438
EF-hand_5 EF hand 5.8E-05 13 25.90 416 437
EFhand_Ca_insen Ca2+ insensitive EF hand 4.1E-05 14 20.80 446 476
EF-hand_8 EF-hand domain pair 9.9E-05 13 28.00 447 471
EF-hand_11 EF-hand domain 0.07 5 21.70 448 512
SPARC_Ca_bdg Secreted protein acidic and rich in cysteine Ca binding region 5.1E-06 17 21.40 448 508
EF-hand_7 EF-hand domain pair 5E-17 53 30.00 450 511
EF-hand_4 Cytoskeletal-regulatory complex EF hand 6.8E-07 20 21.30 451 511
EF-hand_6 EF-hand domain 1.3E-10 31 25.00 451 478
EF-hand_1 EF hand 2.4E-10 30 25.40 452 477
EF-hand_5 EF hand 3.7E-07 20 25.90 453 473
EF-hand_9 EF-hand domain 1.1E-05 16 37.00 454 511
EF-hand_14 EF-hand domain 0.022 6 23.70 455 495
EF-hand_8 EF-hand domain pair 1.9E-11 34 28.00 463 511
EF-hand_1 EF hand 6.6E-11 32 25.40 486 512
EF-hand_6 EF-hand domain 1.3E-05 15 25.00 486 512
EF-hand_5 EF hand 3.3E-05 14 25.90 487 506

521

Pkinase
PK_Tyr_Ser-Thr
Kinase-like
APH
Kdo
DUF4590
DUF4590
Kinase-like
APH
EF-hand_14
DUF2922
AbiJ_NTD4
SPARC_Ca_bdg
EF-hand_4
EF-hand_7
EF-hand_1
EF-hand_6
EF-hand_5
EF-hand_8
EF-hand_9
EF-hand_11
EF-hand_14
DUF2922
EF-hand_8
EFhand_Ca_insen
EF-hand_1
EF-hand_6
EF-hand_5
EFhand_Ca_insen
EF-hand_8
EF-hand_11
SPARC_Ca_bdg
EF-hand_7
EF-hand_4
EF-hand_6
EF-hand_1
EF-hand_5
EF-hand_9
EF-hand_14
EF-hand_8
EF-hand_1
EF-hand_6
EF-hand_5

References:

APH
2163618 Cloning of aminoglycoside phosphotransferase (APH) gene from antibiotic- producing strain of Bacillus circulans into a high-expression vector, pKK223-3. Purification, properties and location of the enzyme [published erratum appears in Biochem J 1991 Feb 1 Biochem J 1990;268:671-677.
2167474 PCR cloning of a streptomycin phosphotransferase (aphE) gene from Streptomyces griseus ATCC 12475. Nucleic Acids Res 1990;18:4615-4615.

EFhand_Ca_insen
11573089 Ca2+-independent binding of an EF-hand domain to a novel motif in the alpha-actinin-titin complex. Nat Struct Biol. 2001;8:853-857.

EF-hand_9

SPARC_Ca_bdg
16121393 The C-terminal Ca2+-binding domain of SPARC confers anti-spreading activity to human urothelial cells. J Cell Physiol. 2006;206:211-220.

EF-hand_7

EF-hand_6

Kdo
11069912 Purification and characterization of WaaP from Escherichia coli, a lipopolysaccharide kinase essential for outer membrane stability. J Biol Chem 2001;276:5498-5504.
12021457 Lipopolysaccharide phosphorylating enzymes encoded in the genomes of Gram-negative bacteria are related to the eukaryotic protein kinases. Protein Sci 2002;11:1580-1584.
10531340 A Haemophilus influenzae gene that encodes a membrane bound 3-deoxy-D-manno-octulosonic acid (Kdo) kinase. Possible involvement of kdo phosphorylation in bacterial virulence. J Biol Chem 1999;274:31391-31400.

EF-hand_4

DUF2922

EF-hand_14

Kinase-like

DUF4590

EF-hand_1

Pkinase
1956325 Protein kinase catalytic domain sequence database: identification of conserved features of primary structure and classification of family members. Methods Enzymol 1991;200:38-62.
7768349 Protein kinases 6. The eukaryotic protein kinase superfamily: kinase (catalytic) domain structure and classification. FASEB J 1995;9:576-596.
9020587 The protein kinases of budding yeast: six score and more. Trends Biochem Sci 1997;22:18-22.

EF-hand_5

EF-hand_11

EF-hand_8

PK_Tyr_Ser-Thr

AbiJ_NTD4

Domain	Description	Evalue	Bits	GA	Start	End
Pkinase	Protein kinase domain	0	254	20.40	73	331
PK_Tyr_Ser-Thr	Protein tyrosine and serine/threonine kinase	3.7E-34	109	23.10	74	326
Kinase-like	Kinase-like	0.5	0	25.00	79	130
APH	Phosphotransferase enzyme family	0.022	5	22.40	87	161
Kdo	Lipopolysaccharide kinase (Kdo/WaaP) family	2.6E-07	21	20.90	104	213
DUF4590	Domain of unknown function (DUF4590)	0.0022	8	27.00	114	149
DUF4590	Domain of unknown function (DUF4590)	0.23	2	27.00	170	226
Kinase-like	Kinase-like	1.2E-06	18	25.00	171	319
APH	Phosphotransferase enzyme family	0.0036	7	22.40	192	211
EF-hand_14	EF-hand domain	0.81	1	23.70	305	357
DUF2922	Protein of unknown function (DUF2922)	0.24	2	22.50	356	378
AbiJ_NTD4	AbiJ N-terminal domain 4	0.0001	13	34.00	361	481
SPARC_Ca_bdg	Secreted protein acidic and rich in cysteine Ca binding region	0.00011	13	21.40	368	436
EF-hand_4	Cytoskeletal-regulatory complex EF hand	1.7E-05	15	21.30	371	438
EF-hand_7	EF-hand domain pair	8.2E-14	42	30.00	379	439
EF-hand_1	EF hand	3.5E-10	29	25.40	379	406
EF-hand_6	EF-hand domain	6.8E-08	23	25.00	379	407
EF-hand_5	EF hand	1.1E-07	22	25.90	379	401
EF-hand_8	EF-hand domain pair	1.9E-05	15	28.00	381	404
EF-hand_9	EF-hand domain	0.00044	11	37.00	381	438
EF-hand_11	EF-hand domain	0.0037	9	21.70	381	437
EF-hand_14	EF-hand domain	0.1	3	23.70	382	422
DUF2922	Protein of unknown function (DUF2922)	0.0023	8	22.50	390	420
EF-hand_8	EF-hand domain pair	6.2E-11	32	28.00	391	438
EFhand_Ca_insen	Ca2+ insensitive EF hand	0.011	6	20.80	394	440
EF-hand_1	EF hand	5.9E-07	19	25.40	414	438
EF-hand_6	EF-hand domain	0.00076	10	25.00	416	438
EF-hand_5	EF hand	5.8E-05	13	25.90	416	437
EFhand_Ca_insen	Ca2+ insensitive EF hand	4.1E-05	14	20.80	446	476
EF-hand_8	EF-hand domain pair	9.9E-05	13	28.00	447	471
EF-hand_11	EF-hand domain	0.07	5	21.70	448	512
SPARC_Ca_bdg	Secreted protein acidic and rich in cysteine Ca binding region	5.1E-06	17	21.40	448	508
EF-hand_7	EF-hand domain pair	5E-17	53	30.00	450	511
EF-hand_4	Cytoskeletal-regulatory complex EF hand	6.8E-07	20	21.30	451	511
EF-hand_6	EF-hand domain	1.3E-10	31	25.00	451	478
EF-hand_1	EF hand	2.4E-10	30	25.40	452	477
EF-hand_5	EF hand	3.7E-07	20	25.90	453	473
EF-hand_9	EF-hand domain	1.1E-05	16	37.00	454	511
EF-hand_14	EF-hand domain	0.022	6	23.70	455	495
EF-hand_8	EF-hand domain pair	1.9E-11	34	28.00	463	511
EF-hand_1	EF hand	6.6E-11	32	25.40	486	512
EF-hand_6	EF-hand domain	1.3E-05	15	25.00	486	512
EF-hand_5	EF hand	3.3E-05	14	25.90	487	506