c2pfam

AT1G56510.1 :

Domain Description Evalue Bits GA Start End
TIR TIR domain 0 162 21.20 13 186
TIR_2 TIR domain 2E-11 35 28.00 15 110
AAA_16 AAA ATPase domain 6.4E-08 24 32.60 187 302
ATPase_2 ATPase domain predominantly from Archaea 5.6E-06 17 33.20 190 304
Sigma54_activat Sigma-54 interaction domain 0.00034 11 20.20 191 233
NB-ARC NB-ARC domain 9.1E-24 74 23.50 193 411
Rad17 Rad17 cell cycle checkpoint protein 1.4E-06 19 19.70 201 301
RsgA_GTPase RsgA GTPase 0.00075 10 30.00 206 232
PhoH PhoH-like protein 0.012 5 20.10 206 227
AAA_14 AAA domain 2.7E-05 15 27.00 208 330
ABC_tran ABC transporter 7.4E-05 14 23.10 208 232
AAA_22 AAA domain 1.2E-06 19 27.00 209 311
AAA_18 AAA domain 5.9E-07 20 29.40 210 328
NACHT NACHT domain 8.2E-05 13 20.40 210 304
Cytidylate_kin Cytidylate kinase 0.00023 11 20.40 211 235
AAA ATPase family associated with various cellular activities (AAA) 4E-05 14 20.80 212 305
PhoH PhoH-like protein 0.0011 9 20.10 261 329
LRR_8 Leucine rich repeat 0.001 9 27.00 602 656
LRR_3 Leucine Rich Repeat 2.3E-10 30 20.20 602 621
LRR_4 Leucine Rich repeats (2 copies) 3.2E-05 15 27.00 625 657
LRR_8 Leucine rich repeat 0.011 6 27.00 648 703
LRR_4 Leucine Rich repeats (2 copies) 0.00044 11 27.00 683 713
LRR_4 Leucine Rich repeats (2 copies) 0.74 1 27.00 725 751
LRR_8 Leucine rich repeat 0.78 0 27.00 731 752
LRR_8 Leucine rich repeat 0.0019 8 27.00 762 794
LRR_4 Leucine Rich repeats (2 copies) 0.012 7 27.00 778 804
LRR_4 Leucine Rich repeats (2 copies) 0.072 4 27.00 785 822

1007

TIR
TIR_2
AAA_16
ATPase_2
Sigma54_activat
NB-ARC
Rad17
RsgA_GTPase
PhoH
AAA_14
ABC_tran
AAA_22
AAA_18
NACHT
Cytidylate_kin
AAA
PhoH
LRR_8
LRR_3
LRR_4
LRR_8
LRR_4
LRR_4
LRR_8
LRR_8
LRR_4
LRR_4

References:

AAA_16

AAA_14

ABC_tran
1864505 Homology between proteins controlling Streptomyces fradiae tylosin resistance and ATP-binding transport. Gene 1991;102:27-32.
1977073 Structure and function of haemolysin B,P-glycoprotein and other members of a novel family of membrane translocators. Mol Microbiol 1990;4:873-880.
2229036 Binding protein-dependent transport systems. J Bioenerg Biomembr 1990;22:571-592.
9872322 Crystal structure of the ATP-binding subunit of an ABC transporter. Nature 1998;396:703-707.

PhoH
8444794 Molecular analysis of the phoH gene, belonging to the phosphate regulon in Escherichia coli. J Bacteriol 1993;175:1316-1324.

RsgA_GTPase

Cytidylate_kin
9862805 Structures of escherichia coli CMP kinase alone and in complex with CDP: a new fold of the nucleoside monophosphate binding domain and insights into cytosine nucleotide specificity. Structure 1998;6:1517-1527.

NB-ARC
9545207 The NB-ARC domain: a novel signalling motif shared by plant resistance gene products and regulators of cell death in animals. Curr Biol 1998;8:226-227.

LRR_8

Sigma54_activat
11544185 Binding of transcriptional activators to sigma 54 in the presence of the transition state analog ADP-aluminum fluoride: insights into activator mechanochemical action. Genes Dev 2001;15:2282-2294.
12618438 Domain Architectures of sigma(54)-Dependent Transcriptional Activators. J Bacteriol 2003;185:1757-1767.

LRR_4

ATPase_2

NACHT
10782090 The NACHT family - a new group of predicted NTPases implicated in apoptosis and MHC transcription activation. Trends Biochem Sci 2000;25:223-224.

LRR_3
7817399 The leucine-rich repeat: a versatile binding motif. Trends Biochem Sci 1994;19:415-421.
8264799 Crystal structure of porcine ribonuclease inhibitor, a protein with leucine-rich repeats. Nature 1993;366:751-756.

Rad17
10208430 hRAD17, a structural homolog of the Schizosaccharomyces pombe RAD17 cell cycle checkpoint gene, stimulates p53 accumulation. Oncogene 1999;18:1689-1699.

TIR_2

AAA
7646486 A 200-amino acid ATPase module in search of a basic function. Bioessays 1995;17:639-650.
9927482 AAA+: A class of chaperone-like ATPases associated with the assembly, operation, and disassembly of protein complexes. Genome Res 1999;9:27-43.

TIR
9013863 The cloning and characterization of human MyD88: a member of an IL-1 receptor related family. FEBS Lett 1997;402:81-84.
9237759 A human homologue of the Drosophila Toll protein signals activation of adaptive immunity [see comments] Nature 1997;388:394-397.
12186654 Toll-like receptors: a family of pattern-recognition receptors in mammals. Genome Biol 2002;3:REVIEWS3011.

AAA_22

AAA_18

Domain	Description	Evalue	Bits	GA	Start	End
TIR	TIR domain	0	162	21.20	13	186
TIR_2	TIR domain	2E-11	35	28.00	15	110
AAA_16	AAA ATPase domain	6.4E-08	24	32.60	187	302
ATPase_2	ATPase domain predominantly from Archaea	5.6E-06	17	33.20	190	304
Sigma54_activat	Sigma-54 interaction domain	0.00034	11	20.20	191	233
NB-ARC	NB-ARC domain	9.1E-24	74	23.50	193	411
Rad17	Rad17 cell cycle checkpoint protein	1.4E-06	19	19.70	201	301
RsgA_GTPase	RsgA GTPase	0.00075	10	30.00	206	232
PhoH	PhoH-like protein	0.012	5	20.10	206	227
AAA_14	AAA domain	2.7E-05	15	27.00	208	330
ABC_tran	ABC transporter	7.4E-05	14	23.10	208	232
AAA_22	AAA domain	1.2E-06	19	27.00	209	311
AAA_18	AAA domain	5.9E-07	20	29.40	210	328
NACHT	NACHT domain	8.2E-05	13	20.40	210	304
Cytidylate_kin	Cytidylate kinase	0.00023	11	20.40	211	235
AAA	ATPase family associated with various cellular activities (AAA)	4E-05	14	20.80	212	305
PhoH	PhoH-like protein	0.0011	9	20.10	261	329
LRR_8	Leucine rich repeat	0.001	9	27.00	602	656
LRR_3	Leucine Rich Repeat	2.3E-10	30	20.20	602	621
LRR_4	Leucine Rich repeats (2 copies)	3.2E-05	15	27.00	625	657
LRR_8	Leucine rich repeat	0.011	6	27.00	648	703
LRR_4	Leucine Rich repeats (2 copies)	0.00044	11	27.00	683	713
LRR_4	Leucine Rich repeats (2 copies)	0.74	1	27.00	725	751
LRR_8	Leucine rich repeat	0.78	0	27.00	731	752
LRR_8	Leucine rich repeat	0.0019	8	27.00	762	794
LRR_4	Leucine Rich repeats (2 copies)	0.012	7	27.00	778	804
LRR_4	Leucine Rich repeats (2 copies)	0.072	4	27.00	785	822