AT1G58290.1 :

DomainDescriptionEvalueBitsGAStartEnd
GlutR_NGlutamyl-tRNAGlu reductase, N-terminal domain014221.50100250
Glu_dehyd_CGlucose dehydrogenase C-terminus3.4E-051434.90257351
Shikimate_DHShikimate / quinate 5-dehydrogenase014924.30266407
2-Hacid_dh_CD-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain2.1E-061825.10277347
OCD_Mu_crystallOrnithine cyclodeaminase/mu-crystallin family1.9E-082419.90277362
ThiFThiF family0.000231120.70277308
NAD_binding_7Putative NAD(P)-binding5.4E-051422.10279349
UDPG_MGDP_dh_NUDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain6.9E-082320.50280352
DapB_NDihydrodipicolinate reductase, N-terminus1.8E-051520.80280347
GFO_IDH_MocAOxidoreductase family, NAD-binding Rossmann fold0.000111423.60280353
F420_oxidoredNADP oxidoreductase coenzyme F420-dependent1.1E-092921.60281349
NAD_binding_2NAD binding domain of 6-phosphogluconate dehydrogenase1.8E-082521.00281351
Gp_dh_NGlyceraldehyde 3-phosphate dehydrogenase, NAD binding domain0.000211220.80281311
TrkA_NTrkA-N domain8.5E-082321.70282328
3HCDH_N3-hydroxyacyl-CoA dehydrogenase, NAD binding domain0.000121220.90282321
ApbAKetopantoate reductase PanE/ApbA3.7E-061721.70282321
Sacchrp_dh_NADPSaccharopine dehydrogenase NADP binding domain2E-061925.10283334
KRKR domain7.3E-051322.60285319
NAD_binding_10NAD(P)H-binding 1E-072227.20286383
UDPG_MGDP_dh_NUDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain0.93-120.50403432
GlutR_dimerGlutamyl-tRNAGlu reductase, dimerisation domain1.8E-299322.90421525

 543

GlutR_N
Glu_dehyd_C
Shikimate_DH
2-Hacid_dh_C
OCD_Mu_crystall
ThiF
NAD_binding_7
UDPG_MGDP_dh_N
DapB_N
GFO_IDH_MocA
F420_oxidored
NAD_binding_2
Gp_dh_N
TrkA_N
3HCDH_N
ApbA
Sacchrp_dh_NADP
KR
NAD_binding_10
UDPG_MGDP_dh_N
GlutR_dimer


References:

TrkA_N
9478130 A novel family of predicted phosphoesterases includes Drosophila prune protein and bacterial RecJ exonuclease. Trends Biochem Sci 1998;23:17-19.
8412700 NAD+ binding to the Escherichia coli K(+)-uptake protein TrkA and sequence similarity between TrkA and domains of a family of dehydrogenases suggest a role for NAD+ in bacterial transport. Mol Microbiol 1993;9:533-543.
11292341 Regulatory potential, phyletic distribution and evolution of ancient, intracellular small-molecule-binding domains. J Mol Biol 2001;307:1271-1292.

Shikimate_DH
7556173 The molecular biology of multidomain proteins. Selected examples. Eur J Biochem 1995;232:7-18.

NAD_binding_10

KR

NAD_binding_2

Glu_dehyd_C

ThiF

OCD_Mu_crystall
2644238 Ornithine cyclodeaminase from octopine Ti plasmid Ach5: identification, DNA sequence, enzyme properties, and comparison with gene and enzyme from nopaline Ti plasmid C58. J Bacteriol 1989;171:847-854.
1384048 mu-crystallin is a mammalian homologue of Agrobacterium ornithine cyclodeaminase and is expressed in human retina. Proc Natl Acad Sci U S A 1992;89:9292-9296.

Sacchrp_dh_NADP

DapB_N
8873595 Interaction of pyridine nucleotide substrates with Escherichia coli dihydrodipicolinate reductase: thermodynamic and structural analysis of binary complexes. Biochemistry 1996;35:13294-13302.
9398235 Three-dimensional structure of Escherichia coli dihydrodipicolinate reductase in complex with NADH and the inhibitor 2,6-pyridinedicarboxylate. Biochemistry 1997;36:15081-15088.
7893645 Three-dimensional structure of Escherichia coli dihydrodipicolinate reductase. Biochemistry 1995;34:3502-3512.

GlutR_N
3075378 tRNA(Glu) as a cofactor in delta-aminolevulinate biosynthesis: steps that regulate chlorophyll synthesis. Trends Biochem Sci 1988;13:139-143.

GlutR_dimer
3075378 tRNA(Glu) as a cofactor in delta-aminolevulinate biosynthesis: steps that regulate chlorophyll synthesis. Trends Biochem Sci 1988;13:139-143.

ApbA
9488683 ApbA, the ketopantoate reductase enzyme of Salmonella typhimurium is required for the synthesis of thiamine via the alternative pyrimidine biosynthetic pathway. J Biol Chem 1998;273:5572-5576.
9721324 The panE gene, encoding ketopantoate reductase, maps at 10 minutes and is allelic to apbA in Salmonella typhimurium. J Bacteriol 1998;180:4757-4759.

UDPG_MGDP_dh_N
2470755 Purification and characterization of guanosine diphospho-D-mannose dehydrogenase. A key enzyme in the biosynthesis of alginate by Pseudomonas aeruginosa. J Biol Chem 1989;264:9380-9385.
9013585 Properties and kinetic analysis of UDP-glucose dehydrogenase from group A streptococci. Irreversible inhibition by UDP-chloroacetol. J Biol Chem 1997;272:3416-3422.

Gp_dh_N
7578111 Crystal structure of glycosomal glyceraldehyde-3-phosphate dehydrogenase from Leishmania mexicana: implications for structure-based drug design and a new position for the inorganic phosphate binding site. Biochemistry 1995;34:14975-14986.

F420_oxidored

GFO_IDH_MocA
8994968 The structure of glucose-fructose oxidoreductase from Zymomonas mobilis: an osmoprotective periplasmic enzyme containing non-dissociable NADP. Structure 1996;4:1413-1428.

2-Hacid_dh_C
9126843 Crystal structure of a ternary complex of D-2-hydroxyisocaproate dehydrogenase from Lactobacillus casei, NAD+ and 2-oxoisocaproate at 1.9 A resolution. J Mol Biol 1997;267:640-660.

NAD_binding_7

3HCDH_N
3479790 Structure of L-3-hydroxyacyl-coenzyme A dehydrogenase: preliminary chain tracing at 2.8-A resolution. Proc Natl Acad Sci U S A 1987;84:8262-8266.