c2pfam

AT1G59870.1 :

Domain Description Evalue Bits GA Start End
ABC_trans_N ABC-transporter N-terminal 2.2E-13 42 25.40 49 162
RsgA_GTPase RsgA GTPase 0.0057 8 30.00 146 224
TIP49 TIP49 C-terminus 2.1E-06 18 23.80 168 225
AAA_16 AAA ATPase domain 7.4E-05 14 32.60 183 224
DnaB_C DnaB-like helicase C terminal domain 0.0065 7 20.60 185 222
TsaE Threonylcarbamoyl adenosine biosynthesis protein TsaE 0.034 5 26.60 186 223
ABC_tran ABC transporter 2.5E-16 52 23.10 187 369
T2SSE Type II/IV secretion system protein 0.0011 9 24.90 188 224
AAA_25 AAA domain 5.3E-05 14 27.00 190 218
AAA_29 P-loop containing region of AAA domain 0.00035 12 27.00 195 217
AAA_30 AAA domain 0.03 5 27.00 195 221
Rad17 Rad17 cell cycle checkpoint protein 0.071 4 19.70 196 226
SMC_N RecF/RecN/SMC N terminal domain 0.07 4 40.00 197 387
AAA_22 AAA domain 0.0054 8 27.00 197 223
NACHT NACHT domain 0.042 5 20.40 198 224
Ploopntkinase3 P-loop Nucleotide Kinase3 0.007 7 27.00 198 227
AAA_14 AAA domain 0.015 7 27.00 198 222
AAA_24 AAA domain 0.017 6 27.00 199 217
AAA_23 AAA domain 0.03 6 27.00 199 218
AAA_21 AAA domain, putative AbiEii toxin, Type IV TA system 0.0072 7 27.00 199 218
cobW CobW/HypB/UreG, nucleotide-binding domain 0.015 6 20.70 199 221
AAA_33 AAA domain 0.0028 9 27.00 200 231
PduV-EutP Ethanolamine utilisation - propanediol utilisation 0.07 4 20.50 200 220
RuvB_N Holliday junction DNA helicase ruvB N-terminus 0.0057 8 20.00 200 228
MMR_HSR1 GTPase of unknown function 0.011 7 24.50 201 223
AAA ATPase family associated with various cellular activities (AAA) 0.00081 11 20.80 201 223
AAA_18 AAA domain 0.00079 11 29.40 201 256
AAA_28 AAA domain 0.00072 11 27.00 202 219
NTPase_1 NTPase 0.0033 9 23.90 202 233
AAA_17 AAA domain 0.018 7 27.00 203 233
ABC2_membrane_7 ABC-2 type transporter 3.1E-09 27 22.70 402 457
ABC2_membrane ABC-2 type transporter 0 150 25.50 523 734
ABC2_membrane_3 ABC-2 family transporter protein 0.017 5 31.60 564 789
PDR_assoc Plant PDR ABC transporter associated 8.3E-27 84 22.70 740 801
PDR_CDR CDR ABC transporter 0.027 6 20.50 766 797
DnaB_C DnaB-like helicase C terminal domain 0.11 3 20.60 890 927
ABC_tran ABC transporter 9.5E-22 69 23.10 895 1047
AAA_25 AAA domain 0.0022 9 27.00 900 926
SMC_N RecF/RecN/SMC N terminal domain 0.21 2 40.00 900 925
TsaE Threonylcarbamoyl adenosine biosynthesis protein TsaE 0.026 6 26.60 901 926
AAA_16 AAA ATPase domain 0.0037 9 32.60 903 927
AAA_29 P-loop containing region of AAA domain 0.00014 13 27.00 905 925
RsgA_GTPase RsgA GTPase 0.00029 12 30.00 906 928
AAA_30 AAA domain 0.0061 8 27.00 906 926
AAA_23 AAA domain 0.0043 9 27.00 907 925
AAA_21 AAA domain, putative AbiEii toxin, Type IV TA system 0.0093 7 27.00 907 927
AAA_22 AAA domain 0.014 7 27.00 908 926
AAA_33 AAA domain 0.0016 10 27.00 908 937
NACHT NACHT domain 0.015 6 20.40 908 931
cobW CobW/HypB/UreG, nucleotide-binding domain 0.02 6 20.70 908 926
AAA_24 AAA domain 0.04 5 27.00 909 924
MMR_HSR1 GTPase of unknown function 0.023 6 24.50 909 929
AAA_14 AAA domain 0.22 3 27.00 909 929
Rad17 Rad17 cell cycle checkpoint protein 0.048 5 19.70 909 997
Ploopntkinase3 P-loop Nucleotide Kinase3 0.26 2 27.00 909 926
AAA_28 AAA domain 0.015 7 27.00 909 932
AAA ATPase family associated with various cellular activities (AAA) 0.026 6 20.80 910 1015
AAA_18 AAA domain 0.0049 9 29.40 910 928
PduV-EutP Ethanolamine utilisation - propanediol utilisation 0.03 5 20.50 910 928
RuvB_N Holliday junction DNA helicase ruvB N-terminus 0.44 2 20.00 910 927
NTPase_1 NTPase 0.9 1 23.90 910 925
AAA_17 AAA domain 0.15 4 27.00 911 926
SMC_N RecF/RecN/SMC N terminal domain 0.016 6 40.00 1027 1083
AAA_21 AAA domain, putative AbiEii toxin, Type IV TA system 5.9E-05 14 27.00 1035 1080
NTPase_1 NTPase 0.16 3 23.90 1055 1084
ABC2_membrane_7 ABC-2 type transporter 7.7E-11 33 22.70 1076 1136
ABC2_membrane ABC-2 type transporter 0 198 25.50 1193 1406
ABC2_membrane_3 ABC-2 family transporter protein 3.6E-05 14 31.60 1240 1458
ABC2_membrane_7 ABC-2 type transporter 0.0061 7 22.70 1268 1315
PDR_CDR CDR ABC transporter 6.3E-05 14 20.50 1422 1465
PDR_assoc Plant PDR ABC transporter associated 0.17 3 22.70 1444 1465

1469

ABC_trans_N
RsgA_GTPase
TIP49
AAA_16
DnaB_C
TsaE
ABC_tran
T2SSE
AAA_25
AAA_29
AAA_30
Rad17
SMC_N
AAA_22
NACHT
Ploopntkinase3
AAA_14
AAA_24
AAA_23
AAA_21
cobW
AAA_33
PduV-EutP
RuvB_N
MMR_HSR1
AAA
AAA_18
AAA_28
NTPase_1
AAA_17
ABC2_membrane_7
ABC2_membrane
ABC2_membrane_3
PDR_assoc
PDR_CDR
DnaB_C
ABC_tran
AAA_25
SMC_N
TsaE
AAA_16
AAA_29
RsgA_GTPase
AAA_30
AAA_23
AAA_21
AAA_22
AAA_33
NACHT
cobW
AAA_24
MMR_HSR1
AAA_14
Rad17
Ploopntkinase3
AAA_28
AAA
AAA_18
PduV-EutP
RuvB_N
NTPase_1
AAA_17
SMC_N
AAA_21
NTPase_1
ABC2_membrane_7
ABC2_membrane
ABC2_membrane_3
ABC2_membrane_7
PDR_CDR
PDR_assoc

References:

MMR_HSR1
8180467 Structure and evolution of a member of a new subfamily of GTP-binding proteins mapping to the human MHC class I region. Mamm Genome 1994;5:100-105.

RsgA_GTPase

ABC2_membrane
1303751 A new subfamily of bacterial ABC-type transport systems catalyzing export of drugs and carbohydrates. Protein Sci 1992;1:1326-1332.

AAA
7646486 A 200-amino acid ATPase module in search of a basic function. Bioessays 1995;17:639-650.
9927482 AAA+: A class of chaperone-like ATPases associated with the assembly, operation, and disassembly of protein complexes. Genome Res 1999;9:27-43.

ABC_trans_N

ABC_tran
1864505 Homology between proteins controlling Streptomyces fradiae tylosin resistance and ATP-binding transport. Gene 1991;102:27-32.
1977073 Structure and function of haemolysin B,P-glycoprotein and other members of a novel family of membrane translocators. Mol Microbiol 1990;4:873-880.
2229036 Binding protein-dependent transport systems. J Bioenerg Biomembr 1990;22:571-592.
9872322 Crystal structure of the ATP-binding subunit of an ABC transporter. Nature 1998;396:703-707.

ABC2_membrane_7

PduV-EutP
15516577 Evidence that a B12-adenosyl transferase is encoded within the ethanolamine operon of Salmonella enterica. J Bacteriol. 2004;186:7635-7644.
10464203 The 17-gene ethanolamine (eut) operon of Salmonella typhimurium encodes five homologues of carboxysome shell proteins. J Bacteriol 1999;181:5317-5329.
10498708 The propanediol utilization (pdu) operon of Salmonella enterica serovar Typhimurium LT2 includes genes necessary for formation of polyhedral organelles involved in coenzyme B(12)-dependent 1, 2-propanediol degradation. J Bacteriol. 1999;181:5967-5975.

TsaE

PDR_CDR
12709320 Functional Similarities and Differences between Candida albicans Cdr1p and Cdr2p Transporters. Antimicrob Agents Chemother 2003;47:1543-1554.

PDR_assoc
12430018 The plant PDR family of ABC transporters. Planta 2002;216:95-106.

ABC2_membrane_3

NTPase_1

RuvB_N
12423347 The RuvABC resolvasome. Eur J Biochem 2002;269:5492-5501.

AAA_16

NACHT
10782090 The NACHT family - a new group of predicted NTPases implicated in apoptosis and MHC transcription activation. Trends Biochem Sci 2000;25:223-224.

AAA_33

Ploopntkinase3

AAA_30

AAA_29

AAA_28

AAA_25

AAA_24

AAA_23

AAA_22

AAA_21

AAA_18

AAA_17

DnaB_C

TIP49
12464178 Reptin and pontin antagonistically regulate heart growth in zebrafish embryos. Cell 2002;111:661-672.
10902922 Chromosome mapping and expression of human tip49 family genes. DNA Seq 2000;11:145-148.

T2SSE

cobW
9140970 The HypB protein from Bradyrhizobium japonicum can store nickel and is required for the nickel-dependent transcriptional regulation of hydrogenase. Mol Microbiol 1997;24:119-128.
9209019 Characterization of UreG, identification of a UreD-UreF-UreG complex, and evidence suggesting that a nucleotide-binding site in UreG is required for in vivo metallocenter assembly of Klebsiella aerogenes urease. J Bacteriol 1997;179:4081-4086.
8423137 The product of the hypB gene, which is required for nickel incorporation into hydrogenases, is a novel guanine nucleotide-binding protein. J Bacteriol 1993;175:630-635.
1624427 Klebsiella aerogenes urease gene cluster: sequence of ureD and demonstration that four accessory genes (ureD, ureE, ureF, and ureG) are involved in nickel metallocenter biosynthesis. J Bacteriol 1992;174:4324-4330.
1655697 Nucleotide sequence and genetic analysis of a 13.1-kilobase-pair Pseudomonas denitrificans DNA fragment containing five cob genes and identification of structural genes encoding Cob(I)alamin adenosyltransferase, cobyric acid synthase, and bifunctional cob J Bacteriol 1991;173:6074-6087.

AAA_14

Rad17
10208430 hRAD17, a structural homolog of the Schizosaccharomyces pombe RAD17 cell cycle checkpoint gene, stimulates p53 accumulation. Oncogene 1999;18:1689-1699.

SMC_N
10429180 Structural maintenance of chromosomes (SMC) proteins: conserved molecular properties for multiple biological functions. Eur J Biochem 1999;263:6-13.
9640531 SMC protein complexes and higher-order chromosome dynamics. Curr Opin Cell Biol 1998;10:317-322.

Domain	Description	Evalue	Bits	GA	Start	End
ABC_trans_N	ABC-transporter N-terminal	2.2E-13	42	25.40	49	162
RsgA_GTPase	RsgA GTPase	0.0057	8	30.00	146	224
TIP49	TIP49 C-terminus	2.1E-06	18	23.80	168	225
AAA_16	AAA ATPase domain	7.4E-05	14	32.60	183	224
DnaB_C	DnaB-like helicase C terminal domain	0.0065	7	20.60	185	222
TsaE	Threonylcarbamoyl adenosine biosynthesis protein TsaE	0.034	5	26.60	186	223
ABC_tran	ABC transporter	2.5E-16	52	23.10	187	369
T2SSE	Type II/IV secretion system protein	0.0011	9	24.90	188	224
AAA_25	AAA domain	5.3E-05	14	27.00	190	218
AAA_29	P-loop containing region of AAA domain	0.00035	12	27.00	195	217
AAA_30	AAA domain	0.03	5	27.00	195	221
Rad17	Rad17 cell cycle checkpoint protein	0.071	4	19.70	196	226
SMC_N	RecF/RecN/SMC N terminal domain	0.07	4	40.00	197	387
AAA_22	AAA domain	0.0054	8	27.00	197	223
NACHT	NACHT domain	0.042	5	20.40	198	224
Ploopntkinase3	P-loop Nucleotide Kinase3	0.007	7	27.00	198	227
AAA_14	AAA domain	0.015	7	27.00	198	222
AAA_24	AAA domain	0.017	6	27.00	199	217
AAA_23	AAA domain	0.03	6	27.00	199	218
AAA_21	AAA domain, putative AbiEii toxin, Type IV TA system	0.0072	7	27.00	199	218
cobW	CobW/HypB/UreG, nucleotide-binding domain	0.015	6	20.70	199	221
AAA_33	AAA domain	0.0028	9	27.00	200	231
PduV-EutP	Ethanolamine utilisation - propanediol utilisation	0.07	4	20.50	200	220
RuvB_N	Holliday junction DNA helicase ruvB N-terminus	0.0057	8	20.00	200	228
MMR_HSR1	GTPase of unknown function	0.011	7	24.50	201	223
AAA	ATPase family associated with various cellular activities (AAA)	0.00081	11	20.80	201	223
AAA_18	AAA domain	0.00079	11	29.40	201	256
AAA_28	AAA domain	0.00072	11	27.00	202	219
NTPase_1	NTPase	0.0033	9	23.90	202	233
AAA_17	AAA domain	0.018	7	27.00	203	233
ABC2_membrane_7	ABC-2 type transporter	3.1E-09	27	22.70	402	457
ABC2_membrane	ABC-2 type transporter	0	150	25.50	523	734
ABC2_membrane_3	ABC-2 family transporter protein	0.017	5	31.60	564	789
PDR_assoc	Plant PDR ABC transporter associated	8.3E-27	84	22.70	740	801
PDR_CDR	CDR ABC transporter	0.027	6	20.50	766	797
DnaB_C	DnaB-like helicase C terminal domain	0.11	3	20.60	890	927
ABC_tran	ABC transporter	9.5E-22	69	23.10	895	1047
AAA_25	AAA domain	0.0022	9	27.00	900	926
SMC_N	RecF/RecN/SMC N terminal domain	0.21	2	40.00	900	925
TsaE	Threonylcarbamoyl adenosine biosynthesis protein TsaE	0.026	6	26.60	901	926
AAA_16	AAA ATPase domain	0.0037	9	32.60	903	927
AAA_29	P-loop containing region of AAA domain	0.00014	13	27.00	905	925
RsgA_GTPase	RsgA GTPase	0.00029	12	30.00	906	928
AAA_30	AAA domain	0.0061	8	27.00	906	926
AAA_23	AAA domain	0.0043	9	27.00	907	925
AAA_21	AAA domain, putative AbiEii toxin, Type IV TA system	0.0093	7	27.00	907	927
AAA_22	AAA domain	0.014	7	27.00	908	926
AAA_33	AAA domain	0.0016	10	27.00	908	937
NACHT	NACHT domain	0.015	6	20.40	908	931
cobW	CobW/HypB/UreG, nucleotide-binding domain	0.02	6	20.70	908	926
AAA_24	AAA domain	0.04	5	27.00	909	924
MMR_HSR1	GTPase of unknown function	0.023	6	24.50	909	929
AAA_14	AAA domain	0.22	3	27.00	909	929
Rad17	Rad17 cell cycle checkpoint protein	0.048	5	19.70	909	997
Ploopntkinase3	P-loop Nucleotide Kinase3	0.26	2	27.00	909	926
AAA_28	AAA domain	0.015	7	27.00	909	932
AAA	ATPase family associated with various cellular activities (AAA)	0.026	6	20.80	910	1015
AAA_18	AAA domain	0.0049	9	29.40	910	928
PduV-EutP	Ethanolamine utilisation - propanediol utilisation	0.03	5	20.50	910	928
RuvB_N	Holliday junction DNA helicase ruvB N-terminus	0.44	2	20.00	910	927
NTPase_1	NTPase	0.9	1	23.90	910	925
AAA_17	AAA domain	0.15	4	27.00	911	926
SMC_N	RecF/RecN/SMC N terminal domain	0.016	6	40.00	1027	1083
AAA_21	AAA domain, putative AbiEii toxin, Type IV TA system	5.9E-05	14	27.00	1035	1080
NTPase_1	NTPase	0.16	3	23.90	1055	1084
ABC2_membrane_7	ABC-2 type transporter	7.7E-11	33	22.70	1076	1136
ABC2_membrane	ABC-2 type transporter	0	198	25.50	1193	1406
ABC2_membrane_3	ABC-2 family transporter protein	3.6E-05	14	31.60	1240	1458
ABC2_membrane_7	ABC-2 type transporter	0.0061	7	22.70	1268	1315
PDR_CDR	CDR ABC transporter	6.3E-05	14	20.50	1422	1465
PDR_assoc	Plant PDR ABC transporter associated	0.17	3	22.70	1444	1465