c2pfam

AT1G63370.1 :

Domain Description Evalue Bits GA Start End
AlaDh_PNT_C Alanine dehydrogenase/PNT, C-terminal domain 3.3E-05 14 20.30 9 44
Glu_dehyd_C Glucose dehydrogenase C-terminus 0.0018 8 34.90 9 44
NAD_binding_7 Putative NAD(P)-binding 0.0012 10 22.10 9 43
Shikimate_DH Shikimate / quinate 5-dehydrogenase 0.0066 7 24.30 9 39
IlvN Acetohydroxy acid isomeroreductase, catalytic domain 0.00029 11 20.60 10 44
K_oxygenase L-lysine 6-monooxygenase (NADPH-requiring) 0.017 5 21.00 11 45
Pyr_redox_2 Pyridine nucleotide-disulphide oxidoreductase 5.5E-17 53 22.80 12 300
DAO FAD dependent oxidoreductase 9.6E-10 29 24.70 12 48
FAD_binding_3 FAD binding domain 5.1E-09 27 20.10 12 43
FMO-like Flavin-binding monooxygenase-like 0 131 19.60 12 240
HI0933_like HI0933-like protein 3E-10 30 20.30 12 46
Thi4 Thi4 family 1.2E-07 22 20.00 12 49
Pyr_redox Pyridine nucleotide-disulphide oxidoreductase 2E-06 19 22.00 12 46
GIDA Glucose inhibited division protein A 4.2E-06 17 20.00 13 42
Lycopene_cycl Lycopene cyclase protein 2E-05 14 23.40 13 45
TrkA_N TrkA-N domain 4.3E-05 15 21.70 13 44
Trp_halogenase Tryptophan halogenase 0.0014 8 19.60 13 42
FAD_binding_2 FAD binding domain 3.2E-10 30 20.40 13 48
FAD_oxidored FAD dependent oxidoreductase 1.4E-08 25 27.00 13 49
NAD_binding_9 FAD-NAD(P)-binding 4.9E-08 24 21.80 14 175
Pyr_redox_3 Pyridine nucleotide-disulphide oxidoreductase 4.5E-07 20 30.00 15 46
NAD_binding_8 NAD(P)-binding Rossmann-like domain 2.2E-13 41 21.90 15 49
YjeF_N YjeF-related protein N-terminus 0.00031 11 22.60 18 41
Amino_oxidase Flavin containing amine oxidoreductase 4.8E-09 27 19.80 21 69
Pyr_redox_3 Pyridine nucleotide-disulphide oxidoreductase 2.7E-15 47 30.00 84 306
K_oxygenase L-lysine 6-monooxygenase (NADPH-requiring) 3E-06 17 21.00 105 241
Trp_halogenase Tryptophan halogenase 0.66 -1 19.60 111 153
DAO FAD dependent oxidoreductase 2.5E-05 15 24.70 112 202
Shikimate_DH Shikimate / quinate 5-dehydrogenase 0.28 2 24.30 205 250
FMO-like Flavin-binding monooxygenase-like 5.3E-19 59 19.60 259 369
NAD_binding_9 FAD-NAD(P)-binding 0.78 0 21.80 265 289
Trp_halogenase Tryptophan halogenase 0.44 0 19.60 269 290
K_oxygenase L-lysine 6-monooxygenase (NADPH-requiring) 0.4 0 21.00 273 290
Glu_dehyd_C Glucose dehydrogenase C-terminus 0.47 1 34.90 275 292
CEP1-DNA_bind CEP-1, DNA binding 0.00043 11 19.80 387 433

450

AlaDh_PNT_C
Glu_dehyd_C
NAD_binding_7
Shikimate_DH
IlvN
K_oxygenase
Pyr_redox_2
DAO
FAD_binding_3
FMO-like
HI0933_like
Thi4
Pyr_redox
GIDA
Lycopene_cycl
TrkA_N
Trp_halogenase
FAD_binding_2
FAD_oxidored
NAD_binding_9
Pyr_redox_3
NAD_binding_8
YjeF_N
Amino_oxidase
Pyr_redox_3
K_oxygenase
Trp_halogenase
DAO
Shikimate_DH
FMO-like
NAD_binding_9
Trp_halogenase
K_oxygenase
Glu_dehyd_C
CEP1-DNA_bind

References:

TrkA_N
9478130 A novel family of predicted phosphoesterases includes Drosophila prune protein and bacterial RecJ exonuclease. Trends Biochem Sci 1998;23:17-19.
8412700 NAD+ binding to the Escherichia coli K(+)-uptake protein TrkA and sequence similarity between TrkA and domains of a family of dehydrogenases suggest a role for NAD+ in bacterial transport. Mol Microbiol 1993;9:533-543.
11292341 Regulatory potential, phyletic distribution and evolution of ancient, intracellular small-molecule-binding domains. J Mol Biol 2001;307:1271-1292.

Shikimate_DH
7556173 The molecular biology of multidomain proteins. Selected examples. Eur J Biochem 1995;232:7-18.

FAD_binding_2
8061609 Structure of glutathione reductase from Escherichia coli at 1.86 A resolution: comparison with the enzyme from human erythrocytes. Protein Sci 1994;3:799-809.

Glu_dehyd_C

NAD_binding_8

Lycopene_cycl
8837512 Functional analysis of the beta and epsilon lycopene cyclase enzymes of Arabidopsis reveals a mechanism for control of cyclic carotenoid formation. Plant Cell 1996;8:1613-1626.
11226339 One ring or two? Determination of ring number in carotenoids by lycopene epsilon-cyclases. Proc Natl Acad Sci U S A 2001;98:2905-2910.

Amino_oxidase
9598979 Maize polyamine oxidase: primary structure from protein and cDNA sequencing. FEBS Lett 1998;426:62-66.
9162023 A key amino acid responsible for substrate selectivity of monoamine oxidase A and B. J Biol Chem 1997;272:14033-14036.
7770050 Cloning, sequencing and heterologous expression of the monoamine oxidase gene from Aspergillus niger. Mol Gen Genet 1995;247:430-438.

Thi4
7961415 Cloning, nucleotide sequence, and regulation of Schizosaccharomyces pombe thi4, a thiamine biosynthetic gene. J Bacteriol 1994;176:6631-6635.

YjeF_N

FAD_binding_3
1409567 Crystal structure of the reduced form of p-hydroxybenzoate hydroxylase refined at 2.3A resolution. Proteins 1992;14:178-190.

Pyr_redox_2
8805537 Protein-protein interactions in the pyruvate dehydrogenase multienzyme complex: dihydrolipoamide dehydrogenase complexed with the binding domain of dihydrolipoamide acetyltransferase. Structure 1996;4:277-286.

DAO
9153426 Active site plasticity in D-amino acid oxidase: a crystallographic analysis. Biochemistry 1997;36:5853-5860.

IlvN
9218783 The crystal structure of plant acetohydroxy acid isomeroreductase complexed with NADPH, two magnesium ions and a herbicidal transition state analog determined at 1.65 A resolution. EMBO J 1997;16:3405-3415.

HI0933_like

Pyr_redox
8805537 Protein-protein interactions in the pyruvate dehydrogenase multienzyme complex: dihydrolipoamide dehydrogenase complexed with the binding domain of dihydrolipoamide acetyltransferase. Structure 1996;4:277-286.

FAD_oxidored

AlaDh_PNT_C
11354603 Lysine metabolism in higher plants. Amino Acids 2001;20:261-279.

CEP1-DNA_bind
15242600 Structural differences in the DNA binding domains of human p53 and its C. elegans ortholog Cep-1. Structure. 2004;12:1237-1243.

K_oxygenase

GIDA

Trp_halogenase
10547442 Conservation of the pyrrolnitrin biosynthetic gene cluster among six pyrrolnitrin-producing strains. FEMS Microbiol Lett 1999;180:39-44.

NAD_binding_9

Pyr_redox_3

NAD_binding_7

FMO-like
9538688 A hydrophobic sequence motif common to N-hydroxylating enzymes. Trends Biochem Sci 1998;23:56-57.

Domain	Description	Evalue	Bits	GA	Start	End
AlaDh_PNT_C	Alanine dehydrogenase/PNT, C-terminal domain	3.3E-05	14	20.30	9	44
Glu_dehyd_C	Glucose dehydrogenase C-terminus	0.0018	8	34.90	9	44
NAD_binding_7	Putative NAD(P)-binding	0.0012	10	22.10	9	43
Shikimate_DH	Shikimate / quinate 5-dehydrogenase	0.0066	7	24.30	9	39
IlvN	Acetohydroxy acid isomeroreductase, catalytic domain	0.00029	11	20.60	10	44
K_oxygenase	L-lysine 6-monooxygenase (NADPH-requiring)	0.017	5	21.00	11	45
Pyr_redox_2	Pyridine nucleotide-disulphide oxidoreductase	5.5E-17	53	22.80	12	300
DAO	FAD dependent oxidoreductase	9.6E-10	29	24.70	12	48
FAD_binding_3	FAD binding domain	5.1E-09	27	20.10	12	43
FMO-like	Flavin-binding monooxygenase-like	0	131	19.60	12	240
HI0933_like	HI0933-like protein	3E-10	30	20.30	12	46
Thi4	Thi4 family	1.2E-07	22	20.00	12	49
Pyr_redox	Pyridine nucleotide-disulphide oxidoreductase	2E-06	19	22.00	12	46
GIDA	Glucose inhibited division protein A	4.2E-06	17	20.00	13	42
Lycopene_cycl	Lycopene cyclase protein	2E-05	14	23.40	13	45
TrkA_N	TrkA-N domain	4.3E-05	15	21.70	13	44
Trp_halogenase	Tryptophan halogenase	0.0014	8	19.60	13	42
FAD_binding_2	FAD binding domain	3.2E-10	30	20.40	13	48
FAD_oxidored	FAD dependent oxidoreductase	1.4E-08	25	27.00	13	49
NAD_binding_9	FAD-NAD(P)-binding	4.9E-08	24	21.80	14	175
Pyr_redox_3	Pyridine nucleotide-disulphide oxidoreductase	4.5E-07	20	30.00	15	46
NAD_binding_8	NAD(P)-binding Rossmann-like domain	2.2E-13	41	21.90	15	49
YjeF_N	YjeF-related protein N-terminus	0.00031	11	22.60	18	41
Amino_oxidase	Flavin containing amine oxidoreductase	4.8E-09	27	19.80	21	69
Pyr_redox_3	Pyridine nucleotide-disulphide oxidoreductase	2.7E-15	47	30.00	84	306
K_oxygenase	L-lysine 6-monooxygenase (NADPH-requiring)	3E-06	17	21.00	105	241
Trp_halogenase	Tryptophan halogenase	0.66	-1	19.60	111	153
DAO	FAD dependent oxidoreductase	2.5E-05	15	24.70	112	202
Shikimate_DH	Shikimate / quinate 5-dehydrogenase	0.28	2	24.30	205	250
FMO-like	Flavin-binding monooxygenase-like	5.3E-19	59	19.60	259	369
NAD_binding_9	FAD-NAD(P)-binding	0.78	0	21.80	265	289
Trp_halogenase	Tryptophan halogenase	0.44	0	19.60	269	290
K_oxygenase	L-lysine 6-monooxygenase (NADPH-requiring)	0.4	0	21.00	273	290
Glu_dehyd_C	Glucose dehydrogenase C-terminus	0.47	1	34.90	275	292
CEP1-DNA_bind	CEP-1, DNA binding	0.00043	11	19.80	387	433