AT1G64230.1 :
Domain
Description
Evalue
Bits
GA
Start
End
UQ_con
Ubiquitin-conjugating enzyme
0
182
20.40
5
141
Prok-E2_B
Prokaryotic E2 family B
4.2E-07
18
25.40
45
116
RWD
RWD domain
2.6E-07
19
20.80
50
111
UEV
UEV domain
4.4E-06
15
20.60
52
109
148
UQ_con
Prok-E2_B
RWD
UEV
References:
UQ_con
1321826
Three-dimensional structure of a ubiquitin-conjugating enzyme (E2).
J Biol Chem 1992;267:15116-15121.
8268156
Tertiary structures of class I ubiquitin-conjugating enzymes are highly conserved: crystal structure of yeast Ubc4.
Biochemistry 1993;32:13809-13817.
9048545
Crystal structure of a class I ubiquitin conjugating enzyme (Ubc7) from Saccharomyces cerevisiae at 2.9 angstroms resolution.
Biochemistry 1997;36:1621-1627.
9241264
TSG101 may be the prototype of a class of dominant negative ubiquitin regulators.
Nat Genet 1997;16:330-331.
9253709
The breast cancer gene product TSG101: a regulator of ubiquitination?
J Mol Med 1997;75:467-469.
18276160
Anatomy of the E2 ligase fold: implications for enzymology and evolution of ubiquitin/Ub-like protein conjugation.
J Struct Biol. 2008;162:205-218.
Prok-E2_B
RWD
11779830
Systematic identification of novel protein domain families associated with nuclear functions.
Genome Res 2002;12:47-56.
15273307
Solution structure of the RWD domain of the mouse GCN2 protein.
Protein Sci 2004;13:2089-2100.
UEV
12482969
Tsg101 is essential for cell growth, proliferation, and cell survival of embryonic and adult tissues.
Mol Cell Biol 2003;23:150-162.
15053872
Ubiquitin recognition by the human TSG101 protein.
Mol Cell 2004;13:783-789.