c2pfam

AT1G64440.1 :

Domain Description Evalue Bits GA Start End
KR KR domain 1E-07 22 22.60 3 88
RmlD_sub_bind RmlD substrate binding domain 8.9E-14 41 19.80 4 166
Epimerase NAD dependent epimerase/dehydratase family 0 183 20.60 5 267
Polysacc_synt_2 Polysaccharide biosynthesis protein 2.7E-16 49 20.20 5 185
adh_short short chain dehydrogenase 2.2E-07 20 20.50 5 82
NmrA NmrA-like family 7.9E-05 12 20.60 5 78
GDP_Man_Dehyd GDP-mannose 4,6 dehydratase 0 232 27.00 6 329
3Beta_HSD 3-beta hydroxysteroid dehydrogenase/isomerase family 4.6E-16 48 20.00 6 140
NAD_binding_10 NAD(P)H-binding 6.6E-10 29 27.20 9 142
Methyltransf_25 Methyltransferase domain 0.00075 10 27.00 36 93
NAD_binding_4 Male sterility protein 0.0006 9 20.10 76 138
KR KR domain 0.86 -1 22.60 114 130
3Beta_HSD 3-beta hydroxysteroid dehydrogenase/isomerase family 0.0012 7 20.00 224 258
Polysacc_synt_2 Polysaccharide biosynthesis protein 0.22 0 20.20 262 305
Methyltransf_25 Methyltransferase domain 0.41 1 27.00 263 282

348

KR
RmlD_sub_bind
Epimerase
Polysacc_synt_2
adh_short
NmrA
GDP_Man_Dehyd
3Beta_HSD
NAD_binding_10
Methyltransf_25
NAD_binding_4
KR
3Beta_HSD
Polysacc_synt_2
Methyltransf_25

References:

NmrA
11726498 The structure of the negative transcriptional regulator NmrA reveals a structural superfamily which includes the short-chain dehydrogenase/reductases. EMBO J 2001;20:6619-6626.

KR

adh_short
9735295 The refined crystal structure of Drosophila lebanonensis alcohol dehydrogenase at 1.9 A resolution. J Mol Biol 1998;282:383-399.
10387002 Structure of tropinone reductase-II complexed with NADP+ and pseudotropine at 1.9 A resolution: implication for stereospecific substrate binding and catalysis. Biochemistry 1999;38:7630-7637.

GDP_Man_Dehyd

NAD_binding_4
9351246 The Arabidopsis MALE STERILITY 2 protein shares similarity with reductases in elongation/condensation complexes. Plant J 1997;12:615-623.

Methyltransf_25

Epimerase
9174344 Structural analysis of UDP-sugar binding to UDP-galactose 4-epimerase from Escherichia coli. Biochemistry 1997;36:6294-6304.

3Beta_HSD
1562516 Structure and tissue-specific expression of 3 beta-hydroxysteroid dehydrogenase/5-ene-4-ene isomerase genes in human and rat classical and peripheral steroidogenic tissues. J Steroid Biochem Mol Biol 1992;41:421-435.

Polysacc_synt_2
7961465 Sequence analysis and molecular characterization of genes required for the biosynthesis of type 1 capsular polysaccharide in Staphylococcus aureus. J Bacteriol 1994;176:7005-7016.
9079898 Identification of additional genes required for O-antigen biosynthesis in Vibrio cholerae O1. J Bacteriol 1997;179:2147-2153.

NAD_binding_10

RmlD_sub_bind
12057193 Variation on a Theme of SDR. dTDP-6-Deoxy-L- lyxo-4-Hexulose Reductase (RmlD) Shows a New Mg(2+)-Dependent Dimerization Mode. Structure (Camb) 2002;10:773-786.
10802738 RmlC, the third enzyme of dTDP-L-rhamnose pathway, is a new class of epimerase. Nat Struct Biol 2000;7:398-402.

Domain	Description	Evalue	Bits	GA	Start	End
KR	KR domain	1E-07	22	22.60	3	88
RmlD_sub_bind	RmlD substrate binding domain	8.9E-14	41	19.80	4	166
Epimerase	NAD dependent epimerase/dehydratase family	0	183	20.60	5	267
Polysacc_synt_2	Polysaccharide biosynthesis protein	2.7E-16	49	20.20	5	185
adh_short	short chain dehydrogenase	2.2E-07	20	20.50	5	82
NmrA	NmrA-like family	7.9E-05	12	20.60	5	78
GDP_Man_Dehyd	GDP-mannose 4,6 dehydratase	0	232	27.00	6	329
3Beta_HSD	3-beta hydroxysteroid dehydrogenase/isomerase family	4.6E-16	48	20.00	6	140
NAD_binding_10	NAD(P)H-binding	6.6E-10	29	27.20	9	142
Methyltransf_25	Methyltransferase domain	0.00075	10	27.00	36	93
NAD_binding_4	Male sterility protein	0.0006	9	20.10	76	138
KR	KR domain	0.86	-1	22.60	114	130
3Beta_HSD	3-beta hydroxysteroid dehydrogenase/isomerase family	0.0012	7	20.00	224	258
Polysacc_synt_2	Polysaccharide biosynthesis protein	0.22	0	20.20	262	305
Methyltransf_25	Methyltransferase domain	0.41	1	27.00	263	282