c2pfam

AT1G66090.1 :

Domain Description Evalue Bits GA Start End
TIR TIR domain 0 169 21.20 26 202
TIR_2 TIR domain 1E-13 43 28.00 31 121
NTPase_1 NTPase 0.41 1 23.90 38 94
NAD_binding_6 Ferric reductase NAD binding domain 0.00017 13 21.60 41 120
DUF4062 Domain of unknown function (DUF4062) 0.00057 11 24.70 46 92
DUF1863 MTH538 TIR-like domain (DUF1863) 0.00075 11 21.20 58 101
NB-ARC NB-ARC domain 0.91 -1 23.50 165 203
IstB_IS21 IstB-like ATP binding protein 0.00024 12 24.10 191 240
Adeno_IVa2 Adenovirus IVa2 protein 8.5E-06 16 20.10 192 241
NB-ARC NB-ARC domain 7.3E-21 65 23.50 205 411
ATPase_2 ATPase domain predominantly from Archaea 3.7E-05 15 33.20 206 318
AAA_16 AAA ATPase domain 1.6E-07 23 32.60 207 289
ABC_tran ABC transporter 3.7E-06 18 23.10 213 246
Rad17 Rad17 cell cycle checkpoint protein 1.7E-06 19 19.70 214 314
PhoH PhoH-like protein 0.003 8 20.10 219 239
AAA_14 AAA domain 1.4E-05 16 27.00 221 320
AAA_23 AAA domain 0.0002 13 27.00 221 244
Sigma54_activat Sigma-54 interaction domain 0.0004 11 20.20 221 244
AAA_29 P-loop containing region of AAA domain 0.00017 12 27.00 223 246
AAA_18 AAA domain 4.7E-06 18 29.40 223 315
NTPase_1 NTPase 2.7E-05 15 23.90 223 295
NACHT NACHT domain 1.9E-07 22 20.40 223 318
AAA_22 AAA domain 4.5E-08 24 27.00 223 325
Cytidylate_kin Cytidylate kinase 7.4E-05 13 20.40 224 252
KTI12 Chromatin associated protein KTI12 0.00014 12 21.60 225 313
RNA_helicase RNA helicase 0.00057 11 21.50 225 248
Mg_chelatase Magnesium chelatase, subunit ChlI 0.00048 10 20.30 225 247
AAA ATPase family associated with various cellular activities (AAA) 1.3E-05 16 20.80 225 316
Sigma54_activat Sigma-54 interaction domain 0.63 1 20.20 273 307
PhoH PhoH-like protein 0.029 5 20.10 276 338

429

TIR
TIR_2
NTPase_1
NAD_binding_6
DUF4062
DUF1863
NB-ARC
IstB_IS21
Adeno_IVa2
NB-ARC
ATPase_2
AAA_16
ABC_tran
Rad17
PhoH
AAA_14
AAA_23
Sigma54_activat
AAA_29
AAA_18
NTPase_1
NACHT
AAA_22
Cytidylate_kin
KTI12
RNA_helicase
Mg_chelatase
AAA
Sigma54_activat
PhoH

References:

DUF4062

AAA
7646486 A 200-amino acid ATPase module in search of a basic function. Bioessays 1995;17:639-650.
9927482 AAA+: A class of chaperone-like ATPases associated with the assembly, operation, and disassembly of protein complexes. Genome Res 1999;9:27-43.

ABC_tran
1864505 Homology between proteins controlling Streptomyces fradiae tylosin resistance and ATP-binding transport. Gene 1991;102:27-32.
1977073 Structure and function of haemolysin B,P-glycoprotein and other members of a novel family of membrane translocators. Mol Microbiol 1990;4:873-880.
2229036 Binding protein-dependent transport systems. J Bioenerg Biomembr 1990;22:571-592.
9872322 Crystal structure of the ATP-binding subunit of an ABC transporter. Nature 1998;396:703-707.

NAD_binding_6

PhoH
8444794 Molecular analysis of the phoH gene, belonging to the phosphate regulon in Escherichia coli. J Bacteriol 1993;175:1316-1324.

IstB_IS21

RNA_helicase
2546125 Two related superfamilies of putative helicases involved in replication, recombination, repair and expression of DNA and RNA genomes. Nucleic Acids Res 1989;17:4713-4730.

Adeno_IVa2
10684284 Interaction of the adenovirus IVa2 protein with viral packaging sequences. J Virol 2000;74:2687-2693.
8207818 The product of the adenovirus intermediate gene IVa2 is a transcriptional activator of the major late promoter. J Virol 1994;68:4450-4457.

ATPase_2

Cytidylate_kin
9862805 Structures of escherichia coli CMP kinase alone and in complex with CDP: a new fold of the nucleoside monophosphate binding domain and insights into cytosine nucleotide specificity. Structure 1998;6:1517-1527.

NTPase_1

NACHT
10782090 The NACHT family - a new group of predicted NTPases implicated in apoptosis and MHC transcription activation. Trends Biochem Sci 2000;25:223-224.

AAA_29

Sigma54_activat
11544185 Binding of transcriptional activators to sigma 54 in the presence of the transition state analog ADP-aluminum fluoride: insights into activator mechanochemical action. Genes Dev 2001;15:2282-2294.
12618438 Domain Architectures of sigma(54)-Dependent Transcriptional Activators. J Bacteriol 2003;185:1757-1767.

AAA_23

AAA_22

AAA_18

TIR
9013863 The cloning and characterization of human MyD88: a member of an IL-1 receptor related family. FEBS Lett 1997;402:81-84.
9237759 A human homologue of the Drosophila Toll protein signals activation of adaptive immunity [see comments] Nature 1997;388:394-397.
12186654 Toll-like receptors: a family of pattern-recognition receptors in mammals. Genome Biol 2002;3:REVIEWS3011.

AAA_16

DUF1863
10964569 Structure-based functional classification of hypothetical protein MTH538 from Methanobacterium thermoautotrophicum. J Mol Biol. 2000;302:189-203.

KTI12
15772087 Physical and functional interaction between Elongator and the chromatin-associated Kti12 protein. J Biol Chem 2005;280:19454-19460.

Mg_chelatase
9359397 Mechanism and regulation of Mg-chelatase. Biochem J 1997;327:321-333.
9457877 Reconstitution of an active magnesium chelatase enzyme complex from the bchI, -D, and -H gene products of the green sulfur bacterium Chlorobium vibrioforme expressed in Escherichia coli. J Bacteriol 1998;180:699-704.

AAA_14

Rad17
10208430 hRAD17, a structural homolog of the Schizosaccharomyces pombe RAD17 cell cycle checkpoint gene, stimulates p53 accumulation. Oncogene 1999;18:1689-1699.

NB-ARC
9545207 The NB-ARC domain: a novel signalling motif shared by plant resistance gene products and regulators of cell death in animals. Curr Biol 1998;8:226-227.

TIR_2

Domain	Description	Evalue	Bits	GA	Start	End
TIR	TIR domain	0	169	21.20	26	202
TIR_2	TIR domain	1E-13	43	28.00	31	121
NTPase_1	NTPase	0.41	1	23.90	38	94
NAD_binding_6	Ferric reductase NAD binding domain	0.00017	13	21.60	41	120
DUF4062	Domain of unknown function (DUF4062)	0.00057	11	24.70	46	92
DUF1863	MTH538 TIR-like domain (DUF1863)	0.00075	11	21.20	58	101
NB-ARC	NB-ARC domain	0.91	-1	23.50	165	203
IstB_IS21	IstB-like ATP binding protein	0.00024	12	24.10	191	240
Adeno_IVa2	Adenovirus IVa2 protein	8.5E-06	16	20.10	192	241
NB-ARC	NB-ARC domain	7.3E-21	65	23.50	205	411
ATPase_2	ATPase domain predominantly from Archaea	3.7E-05	15	33.20	206	318
AAA_16	AAA ATPase domain	1.6E-07	23	32.60	207	289
ABC_tran	ABC transporter	3.7E-06	18	23.10	213	246
Rad17	Rad17 cell cycle checkpoint protein	1.7E-06	19	19.70	214	314
PhoH	PhoH-like protein	0.003	8	20.10	219	239
AAA_14	AAA domain	1.4E-05	16	27.00	221	320
AAA_23	AAA domain	0.0002	13	27.00	221	244
Sigma54_activat	Sigma-54 interaction domain	0.0004	11	20.20	221	244
AAA_29	P-loop containing region of AAA domain	0.00017	12	27.00	223	246
AAA_18	AAA domain	4.7E-06	18	29.40	223	315
NTPase_1	NTPase	2.7E-05	15	23.90	223	295
NACHT	NACHT domain	1.9E-07	22	20.40	223	318
AAA_22	AAA domain	4.5E-08	24	27.00	223	325
Cytidylate_kin	Cytidylate kinase	7.4E-05	13	20.40	224	252
KTI12	Chromatin associated protein KTI12	0.00014	12	21.60	225	313
RNA_helicase	RNA helicase	0.00057	11	21.50	225	248
Mg_chelatase	Magnesium chelatase, subunit ChlI	0.00048	10	20.30	225	247
AAA	ATPase family associated with various cellular activities (AAA)	1.3E-05	16	20.80	225	316
Sigma54_activat	Sigma-54 interaction domain	0.63	1	20.20	273	307
PhoH	PhoH-like protein	0.029	5	20.10	276	338