c2pfam

AT1G75290.1 :

Domain Description Evalue Bits GA Start End
AlaDh_PNT_C Alanine dehydrogenase/PNT, C-terminal domain 0.00014 12 20.30 5 85
Shikimate_DH Shikimate / quinate 5-dehydrogenase 0.00076 10 24.30 5 102
F420_oxidored NADP oxidoreductase coenzyme F420-dependent 6.8E-05 14 21.60 7 86
RmlD_sub_bind RmlD substrate binding domain 0.00024 11 19.80 7 82
adh_short short chain dehydrogenase 1.2E-05 15 20.50 7 82
DapB_N Dihydrodipicolinate reductase, N-terminus 1.6E-05 15 20.80 7 82
Polysacc_synt_2 Polysaccharide biosynthesis protein 3E-05 14 20.20 8 82
Sacchrp_dh_NADP Saccharopine dehydrogenase NADP binding domain 8.2E-08 23 25.10 8 96
KR KR domain 2.4E-07 21 22.60 8 79
NmrA NmrA-like family 0 295 20.60 8 242
Epimerase NAD dependent epimerase/dehydratase family 3.7E-10 30 20.60 8 86
3Beta_HSD 3-beta hydroxysteroid dehydrogenase/isomerase family 4.5E-10 29 20.00 9 92
GDP_Man_Dehyd GDP-mannose 4,6 dehydratase 1.6E-08 25 27.00 9 79
XdhC_C XdhC Rossmann domain 0.0003 12 29.70 9 89
TrkA_N TrkA-N domain 1.8E-06 19 21.70 10 88
NAD_binding_10 NAD(P)H-binding 1.5E-19 61 27.20 12 171
CCAP Arthropod cardioacceleratory peptide 2a 0.0015 9 20.20 38 104
THF_DHG_CYH_C Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 0.00023 11 20.50 55 96
CCAP Arthropod cardioacceleratory peptide 2a 0.085 3 20.20 227 258

318

AlaDh_PNT_C
Shikimate_DH
F420_oxidored
RmlD_sub_bind
adh_short
DapB_N
Polysacc_synt_2
Sacchrp_dh_NADP
KR
NmrA
Epimerase
3Beta_HSD
GDP_Man_Dehyd
XdhC_C
TrkA_N
NAD_binding_10
CCAP
THF_DHG_CYH_C
CCAP

References:

NAD_binding_10

Sacchrp_dh_NADP

KR

adh_short
9735295 The refined crystal structure of Drosophila lebanonensis alcohol dehydrogenase at 1.9 A resolution. J Mol Biol 1998;282:383-399.
10387002 Structure of tropinone reductase-II complexed with NADP+ and pseudotropine at 1.9 A resolution: implication for stereospecific substrate binding and catalysis. Biochemistry 1999;38:7630-7637.

Polysacc_synt_2
7961465 Sequence analysis and molecular characterization of genes required for the biosynthesis of type 1 capsular polysaccharide in Staphylococcus aureus. J Bacteriol 1994;176:7005-7016.
9079898 Identification of additional genes required for O-antigen biosynthesis in Vibrio cholerae O1. J Bacteriol 1997;179:2147-2153.

3Beta_HSD
1562516 Structure and tissue-specific expression of 3 beta-hydroxysteroid dehydrogenase/5-ene-4-ene isomerase genes in human and rat classical and peripheral steroidogenic tissues. J Steroid Biochem Mol Biol 1992;41:421-435.

CCAP
18521612 Pleiotropic effects of the neuropeptides CCAP and myosuppressin in the beetle, Tenebrio molitor L. J Comp Physiol [B]. 2008; [Epub ahead of print]

DapB_N
8873595 Interaction of pyridine nucleotide substrates with Escherichia coli dihydrodipicolinate reductase: thermodynamic and structural analysis of binary complexes. Biochemistry 1996;35:13294-13302.
9398235 Three-dimensional structure of Escherichia coli dihydrodipicolinate reductase in complex with NADH and the inhibitor 2,6-pyridinedicarboxylate. Biochemistry 1997;36:15081-15088.
7893645 Three-dimensional structure of Escherichia coli dihydrodipicolinate reductase. Biochemistry 1995;34:3502-3512.

RmlD_sub_bind
12057193 Variation on a Theme of SDR. dTDP-6-Deoxy-L- lyxo-4-Hexulose Reductase (RmlD) Shows a New Mg(2+)-Dependent Dimerization Mode. Structure (Camb) 2002;10:773-786.
10802738 RmlC, the third enzyme of dTDP-L-rhamnose pathway, is a new class of epimerase. Nat Struct Biol 2000;7:398-402.

AlaDh_PNT_C
11354603 Lysine metabolism in higher plants. Amino Acids 2001;20:261-279.

Shikimate_DH
7556173 The molecular biology of multidomain proteins. Selected examples. Eur J Biochem 1995;232:7-18.

GDP_Man_Dehyd

TrkA_N
9478130 A novel family of predicted phosphoesterases includes Drosophila prune protein and bacterial RecJ exonuclease. Trends Biochem Sci 1998;23:17-19.
8412700 NAD+ binding to the Escherichia coli K(+)-uptake protein TrkA and sequence similarity between TrkA and domains of a family of dehydrogenases suggest a role for NAD+ in bacterial transport. Mol Microbiol 1993;9:533-543.
11292341 Regulatory potential, phyletic distribution and evolution of ancient, intracellular small-molecule-binding domains. J Mol Biol 2001;307:1271-1292.

THF_DHG_CYH_C
9519408 The 3-D structure of a folate-dependent dehydrogenase/cyclohydrolase bifunctional enzyme at 1.5 A resolution. Structure 1998;6:173-182.

Epimerase
9174344 Structural analysis of UDP-sugar binding to UDP-galactose 4-epimerase from Escherichia coli. Biochemistry 1997;36:6294-6304.

F420_oxidored

NmrA
11726498 The structure of the negative transcriptional regulator NmrA reveals a structural superfamily which includes the short-chain dehydrogenase/reductases. EMBO J 2001;20:6619-6626.

XdhC_C

Domain	Description	Evalue	Bits	GA	Start	End
AlaDh_PNT_C	Alanine dehydrogenase/PNT, C-terminal domain	0.00014	12	20.30	5	85
Shikimate_DH	Shikimate / quinate 5-dehydrogenase	0.00076	10	24.30	5	102
F420_oxidored	NADP oxidoreductase coenzyme F420-dependent	6.8E-05	14	21.60	7	86
RmlD_sub_bind	RmlD substrate binding domain	0.00024	11	19.80	7	82
adh_short	short chain dehydrogenase	1.2E-05	15	20.50	7	82
DapB_N	Dihydrodipicolinate reductase, N-terminus	1.6E-05	15	20.80	7	82
Polysacc_synt_2	Polysaccharide biosynthesis protein	3E-05	14	20.20	8	82
Sacchrp_dh_NADP	Saccharopine dehydrogenase NADP binding domain	8.2E-08	23	25.10	8	96
KR	KR domain	2.4E-07	21	22.60	8	79
NmrA	NmrA-like family	0	295	20.60	8	242
Epimerase	NAD dependent epimerase/dehydratase family	3.7E-10	30	20.60	8	86
3Beta_HSD	3-beta hydroxysteroid dehydrogenase/isomerase family	4.5E-10	29	20.00	9	92
GDP_Man_Dehyd	GDP-mannose 4,6 dehydratase	1.6E-08	25	27.00	9	79
XdhC_C	XdhC Rossmann domain	0.0003	12	29.70	9	89
TrkA_N	TrkA-N domain	1.8E-06	19	21.70	10	88
NAD_binding_10	NAD(P)H-binding	1.5E-19	61	27.20	12	171
CCAP	Arthropod cardioacceleratory peptide 2a	0.0015	9	20.20	38	104
THF_DHG_CYH_C	Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain	0.00023	11	20.50	55	96
CCAP	Arthropod cardioacceleratory peptide 2a	0.085	3	20.20	227	258