AT2G22830.1 :

DomainDescriptionEvalueBitsGAStartEnd
Holin_BhlABhlA holin family0.000481122.6079104
DUF1188Protein of unknown function (DUF1188)0.000461026.50107152
Shikimate_DHShikimate / quinate 5-dehydrogenase6.8E-051424.30121174
AlaDh_PNT_CAlanine dehydrogenase/PNT, C-terminal domain0.000561020.30123157
Thi4Thi4 family2.4E-061820.00123156
FAD_binding_3FAD binding domain7E-216520.10123451
DAOFAD dependent oxidoreductase2.9E-082424.70124156
FAD_binding_2FAD binding domain4.9E-082320.40124155
GIDAGlucose inhibited division protein A5E-072020.00124286
Pyr_redox_2Pyridine nucleotide-disulphide oxidoreductase3.1E-072022.80124156
Lycopene_cyclLycopene cyclase protein2.6E-061723.40124153
FAD_oxidoredFAD dependent oxidoreductase1.1E-051527.00124278
HI0933_likeHI0933-like protein7.9E-061520.30124154
Trp_halogenaseTryptophan halogenase0.0027719.60124153
ApbAKetopantoate reductase PanE/ApbA4.7E-051421.70125155
Pyr_redoxPyridine nucleotide-disulphide oxidoreductase1.6E-051622.00125153
TrkA_NTrkA-N domain7.5E-051421.70125154
NAD_Gly3P_dh_NNAD-dependent glycerol-3-phosphate dehydrogenase N-terminus9.2E-051323.10125161
Pyr_redox_3Pyridine nucleotide-disulphide oxidoreductase0.000311130.00126154
EpimeraseNAD dependent epimerase/dehydratase family0.000361120.60126181
NAD_binding_8NAD(P)-binding Rossmann-like domain2.8E-082521.90127153
DAOFAD dependent oxidoreductase1.6E-061824.70220308
Trp_halogenaseTryptophan halogenase0.25119.60221286
FAD_binding_2FAD binding domain0.011520.40226296
SESqualene epoxidase041420.10273543

 585

Holin_BhlA
DUF1188
Shikimate_DH
AlaDh_PNT_C
Thi4
FAD_binding_3
DAO
FAD_binding_2
GIDA
Pyr_redox_2
Lycopene_cycl
FAD_oxidored
HI0933_like
Trp_halogenase
ApbA
Pyr_redox
TrkA_N
NAD_Gly3P_dh_N
Pyr_redox_3
Epimerase
NAD_binding_8
DAO
Trp_halogenase
FAD_binding_2
SE


References:

TrkA_N
9478130 A novel family of predicted phosphoesterases includes Drosophila prune protein and bacterial RecJ exonuclease. Trends Biochem Sci 1998;23:17-19.
8412700 NAD+ binding to the Escherichia coli K(+)-uptake protein TrkA and sequence similarity between TrkA and domains of a family of dehydrogenases suggest a role for NAD+ in bacterial transport. Mol Microbiol 1993;9:533-543.
11292341 Regulatory potential, phyletic distribution and evolution of ancient, intracellular small-molecule-binding domains. J Mol Biol 2001;307:1271-1292.

Shikimate_DH
7556173 The molecular biology of multidomain proteins. Selected examples. Eur J Biochem 1995;232:7-18.

FAD_binding_2
8061609 Structure of glutathione reductase from Escherichia coli at 1.86 A resolution: comparison with the enzyme from human erythrocytes. Protein Sci 1994;3:799-809.

Epimerase
9174344 Structural analysis of UDP-sugar binding to UDP-galactose 4-epimerase from Escherichia coli. Biochemistry 1997;36:6294-6304.

NAD_binding_8

Lycopene_cycl
8837512 Functional analysis of the beta and epsilon lycopene cyclase enzymes of Arabidopsis reveals a mechanism for control of cyclic carotenoid formation. Plant Cell 1996;8:1613-1626.
11226339 One ring or two? Determination of ring number in carotenoids by lycopene epsilon-cyclases. Proc Natl Acad Sci U S A 2001;98:2905-2910.

ApbA
9488683 ApbA, the ketopantoate reductase enzyme of Salmonella typhimurium is required for the synthesis of thiamine via the alternative pyrimidine biosynthetic pathway. J Biol Chem 1998;273:5572-5576.
9721324 The panE gene, encoding ketopantoate reductase, maps at 10 minutes and is allelic to apbA in Salmonella typhimurium. J Bacteriol 1998;180:4757-4759.

Thi4
7961415 Cloning, nucleotide sequence, and regulation of Schizosaccharomyces pombe thi4, a thiamine biosynthetic gene. J Bacteriol 1994;176:6631-6635.

FAD_binding_3
1409567 Crystal structure of the reduced form of p-hydroxybenzoate hydroxylase refined at 2.3A resolution. Proteins 1992;14:178-190.

Pyr_redox_2
8805537 Protein-protein interactions in the pyruvate dehydrogenase multienzyme complex: dihydrolipoamide dehydrogenase complexed with the binding domain of dihydrolipoamide acetyltransferase. Structure 1996;4:277-286.

DAO
9153426 Active site plasticity in D-amino acid oxidase: a crystallographic analysis. Biochemistry 1997;36:5853-5860.

HI0933_like

Holin_BhlA

DUF1188

GIDA

Pyr_redox
8805537 Protein-protein interactions in the pyruvate dehydrogenase multienzyme complex: dihydrolipoamide dehydrogenase complexed with the binding domain of dihydrolipoamide acetyltransferase. Structure 1996;4:277-286.

FAD_oxidored

AlaDh_PNT_C
11354603 Lysine metabolism in higher plants. Amino Acids 2001;20:261-279.

SE
9161422 Cloning and expression of squalene epoxidase from the pathogenic yeast Candida albicans. Gene 1997;189:119-126.

Trp_halogenase
10547442 Conservation of the pyrrolnitrin biosynthetic gene cluster among six pyrrolnitrin-producing strains. FEMS Microbiol Lett 1999;180:39-44.

Pyr_redox_3

NAD_Gly3P_dh_N
12032156 Kinetic regulation of the mitochondrial glycerol-3-phosphate dehydrogenase by the external NADH dehydrogenase in Saccharomyces cerevisiae. J Biol Chem 2002;277:27991-27995.
10801498 A potential target enzyme for trypanocidal drugs revealed by the crystal structure of NAD-dependent glycerol-3-phosphate dehydrogenase from Leishmania mexicana. Structure Fold Des 2000;8:541-552.