c2pfam

AT2G29940.1 :

Domain Description Evalue Bits GA Start End
ABC_trans_N ABC-transporter N-terminal 6E-13 41 25.40 60 151
RsgA_GTPase RsgA GTPase 0.00011 14 30.00 173 219
ABC_ATPase Predicted ATPase of the ABC class 0.0045 7 19.30 175 207
ABC_tran ABC transporter 2E-20 65 23.10 176 359
TsaE Threonylcarbamoyl adenosine biosynthesis protein TsaE 0.082 5 26.60 176 211
T2SSE Type II/IV secretion system protein 0.0015 9 24.90 177 213
AAA_25 AAA domain 1.4E-05 16 27.00 179 207
AAA_11 AAA domain 0.00062 11 27.00 180 212
AAA_7 P-loop containing dynein motor region 0.0033 9 25.80 182 221
AAA_30 AAA domain 0.0012 10 27.00 185 210
Rad17 Rad17 cell cycle checkpoint protein 0.00067 11 19.70 185 222
AAA_29 P-loop containing region of AAA domain 8.6E-06 17 27.00 185 206
ATPase_2 ATPase domain predominantly from Archaea 0.0027 9 33.20 185 235
TIP49 TIP49 C-terminus 0.00046 11 23.80 185 242
AAA_19 AAA domain 0.0073 8 25.10 185 214
AAA_22 AAA domain 0.00012 14 27.00 186 215
AAA_16 AAA ATPase domain 2.2E-05 17 32.60 186 213
AAA_15 AAA ATPase domain 0.012 7 32.10 186 244
NACHT NACHT domain 0.0012 11 20.40 187 213
Ploopntkinase3 P-loop Nucleotide Kinase3 0.00018 13 27.00 187 216
SMC_N RecF/RecN/SMC N terminal domain 0.00047 11 40.00 187 377
VirE Virulence-associated protein E 0.25 2 21.50 187 209
AAA_14 AAA domain 0.0053 9 27.00 187 232
AAA_24 AAA domain 0.011 7 27.00 188 206
SRP54 SRP54-type protein, GTPase domain 0.062 5 20.50 188 217
AAA_23 AAA domain 0.00032 13 27.00 188 241
AAA_21 AAA domain, putative AbiEii toxin, Type IV TA system 0.0021 10 27.00 188 208
Zeta_toxin Zeta toxin 0.0019 9 20.10 188 254
cobW CobW/HypB/UreG, nucleotide-binding domain 0.0028 9 20.70 188 209
RuvB_N Holliday junction DNA helicase ruvB N-terminus 0.0016 10 20.00 189 218
AAA_33 AAA domain 0.00063 12 27.00 189 211
DUF2075 Uncharacterized conserved protein (DUF2075) 0.0009 10 20.30 189 229
Mg_chelatase Magnesium chelatase, subunit ChlI 0.012 7 20.30 189 209
PduV-EutP Ethanolamine utilisation - propanediol utilisation 0.075 5 20.50 189 222
Septin Septin 0.068 4 20.00 190 258
FeoB_N Ferrous iron transport protein B 0.11 4 21.20 190 210
AAA ATPase family associated with various cellular activities (AAA) 6.7E-05 15 20.80 190 247
AAA_18 AAA domain 0.00014 14 29.40 190 235
Roc Ras of Complex, Roc, domain of DAPkinase 0.038 6 27.00 190 228
RNA_helicase RNA helicase 0.00069 12 21.50 190 231
MMR_HSR1 GTPase of unknown function 0.00053 12 24.50 190 233
AAA_5 AAA domain (dynein-related subfamily) 0.00039 12 20.80 190 213
AAA_28 AAA domain 0.0045 9 27.00 191 208
NTPase_1 NTPase 0.0018 10 23.90 191 223
Dynamin_N Dynamin family 0.65 2 21.00 192 209
AAA_17 AAA domain 0.0015 11 27.00 192 220
Mg_chelatase Magnesium chelatase, subunit ChlI 0.84 1 20.30 333 360
ABC2_membrane_7 ABC-2 type transporter 1.7E-08 25 22.70 392 443
ABC2_membrane ABC-2 type transporter 0 145 25.50 513 725
PDR_assoc Plant PDR ABC transporter associated 7.9E-27 85 22.70 730 793
PDR_CDR CDR ABC transporter 0.54 2 20.50 758 785
VirE Virulence-associated protein E 0.0083 7 21.50 850 888
AAA_16 AAA ATPase domain 0.00058 12 32.60 852 906
ABC_tran ABC transporter 3E-24 78 23.10 854 1006
ABC_ATPase Predicted ATPase of the ABC class 0.13 3 19.30 855 884
AAA_25 AAA domain 0.00018 13 27.00 856 885
TsaE Threonylcarbamoyl adenosine biosynthesis protein TsaE 0.014 7 26.60 860 885
AAA_15 AAA ATPase domain 0.038 5 32.10 861 884
AAA_23 AAA domain 0.00015 14 27.00 861 886
AAA_30 AAA domain 0.0024 9 27.00 862 885
RsgA_GTPase RsgA GTPase 0.0001 14 30.00 865 888
AAA_29 P-loop containing region of AAA domain 7.6E-05 14 27.00 866 884
SMC_N RecF/RecN/SMC N terminal domain 0.0021 9 40.00 866 1040
AAA_21 AAA domain, putative AbiEii toxin, Type IV TA system 5.8E-05 15 27.00 866 931
Zeta_toxin Zeta toxin 0.003 9 20.10 866 935
NACHT NACHT domain 0.026 6 20.40 867 885
cobW CobW/HypB/UreG, nucleotide-binding domain 0.0087 7 20.70 867 885
AAA_22 AAA domain 0.012 8 27.00 867 886
AAA_33 AAA domain 0.0018 10 27.00 867 889
FeoB_N Ferrous iron transport protein B 0.051 5 21.20 867 888
SRP54 SRP54-type protein, GTPase domain 0.1 4 20.50 867 885
Dynamin_N Dynamin family 0.013 7 21.00 868 991
AAA_24 AAA domain 0.071 5 27.00 868 882
AAA_14 AAA domain 0.95 1 27.00 868 887
Roc Ras of Complex, Roc, domain of DAPkinase 0.016 7 27.00 868 903
AAA_7 P-loop containing dynein motor region 0.042 5 25.80 868 918
MMR_HSR1 GTPase of unknown function 0.0048 9 24.50 868 888
AAA_28 AAA domain 0.0084 8 27.00 868 889
Ploopntkinase3 P-loop Nucleotide Kinase3 0.063 5 27.00 868 885
AAA_5 AAA domain (dynein-related subfamily) 0.24 3 20.80 869 886
Rad17 Rad17 cell cycle checkpoint protein 0.35 2 19.70 869 894
RNA_helicase RNA helicase 0.027 7 21.50 869 908
NTPase_1 NTPase 0.86 1 23.90 869 883
RuvB_N Holliday junction DNA helicase ruvB N-terminus 0.44 2 20.00 869 886
AAA ATPase family associated with various cellular activities (AAA) 0.02 7 20.80 869 1004
AAA_18 AAA domain 0.0093 8 29.40 869 943
PduV-EutP Ethanolamine utilisation - propanediol utilisation 0.026 6 20.50 869 887
Septin Septin 0.045 5 20.00 869 888
AAA_17 AAA domain 1 2 27.00 870 885
AAA_21 AAA domain, putative AbiEii toxin, Type IV TA system 0.00011 14 27.00 994 1039
NTPase_1 NTPase 0.51 2 23.90 1014 1042
ABC2_membrane_7 ABC-2 type transporter 8.4E-07 20 22.70 1035 1078
ABC2_membrane ABC-2 type transporter 0 178 25.50 1152 1363
ABC2_membrane_7 ABC-2 type transporter 0.055 4 22.70 1228 1311
PDR_CDR CDR ABC transporter 0.0032 9 20.50 1382 1423
PDR_assoc Plant PDR ABC transporter associated 0.0017 10 22.70 1398 1422

1426

ABC_trans_N
RsgA_GTPase
ABC_ATPase
ABC_tran
TsaE
T2SSE
AAA_25
AAA_11
AAA_7
AAA_30
Rad17
AAA_29
ATPase_2
TIP49
AAA_19
AAA_22
AAA_16
AAA_15
NACHT
Ploopntkinase3
SMC_N
VirE
AAA_14
AAA_24
SRP54
AAA_23
AAA_21
Zeta_toxin
cobW
RuvB_N
AAA_33
DUF2075
Mg_chelatase
PduV-EutP
Septin
FeoB_N
AAA
AAA_18
Roc
RNA_helicase
MMR_HSR1
AAA_5
AAA_28
NTPase_1
Dynamin_N
AAA_17
Mg_chelatase
ABC2_membrane_7
ABC2_membrane
PDR_assoc
PDR_CDR
VirE
AAA_16
ABC_tran
ABC_ATPase
AAA_25
TsaE
AAA_15
AAA_23
AAA_30
RsgA_GTPase
AAA_29
SMC_N
AAA_21
Zeta_toxin
NACHT
cobW
AAA_22
AAA_33
FeoB_N
SRP54
Dynamin_N
AAA_24
AAA_14
Roc
AAA_7
MMR_HSR1
AAA_28
Ploopntkinase3
AAA_5
Rad17
RNA_helicase
NTPase_1
RuvB_N
AAA
AAA_18
PduV-EutP
Septin
AAA_17
AAA_21
NTPase_1
ABC2_membrane_7
ABC2_membrane
ABC2_membrane_7
PDR_CDR
PDR_assoc

References:

MMR_HSR1
8180467 Structure and evolution of a member of a new subfamily of GTP-binding proteins mapping to the human MHC class I region. Mamm Genome 1994;5:100-105.

SRP54
9002525 Crystal structure of the NG domain from the signal-recognition particle receptor FtsY. Nature 1997;385:365-368.

ABC2_membrane
1303751 A new subfamily of bacterial ABC-type transport systems catalyzing export of drugs and carbohydrates. Protein Sci 1992;1:1326-1332.

AAA
7646486 A 200-amino acid ATPase module in search of a basic function. Bioessays 1995;17:639-650.
9927482 AAA+: A class of chaperone-like ATPases associated with the assembly, operation, and disassembly of protein complexes. Genome Res 1999;9:27-43.

ABC_trans_N

ABC_tran
1864505 Homology between proteins controlling Streptomyces fradiae tylosin resistance and ATP-binding transport. Gene 1991;102:27-32.
1977073 Structure and function of haemolysin B,P-glycoprotein and other members of a novel family of membrane translocators. Mol Microbiol 1990;4:873-880.
2229036 Binding protein-dependent transport systems. J Bioenerg Biomembr 1990;22:571-592.
9872322 Crystal structure of the ATP-binding subunit of an ABC transporter. Nature 1998;396:703-707.

ABC2_membrane_7

PduV-EutP
15516577 Evidence that a B12-adenosyl transferase is encoded within the ethanolamine operon of Salmonella enterica. J Bacteriol. 2004;186:7635-7644.
10464203 The 17-gene ethanolamine (eut) operon of Salmonella typhimurium encodes five homologues of carboxysome shell proteins. J Bacteriol 1999;181:5317-5329.
10498708 The propanediol utilization (pdu) operon of Salmonella enterica serovar Typhimurium LT2 includes genes necessary for formation of polyhedral organelles involved in coenzyme B(12)-dependent 1, 2-propanediol degradation. J Bacteriol. 1999;181:5967-5975.

TsaE

DUF2075

PDR_assoc
12430018 The plant PDR family of ABC transporters. Planta 2002;216:95-106.

Septin
12665577 Molecular dissection of a yeast septin: distinct domains are required for septin interaction, localization, and function. Mol Cell Biol 2003;23:2762-2777.
14611653 The septins. Genome Biol 2003;4:236.

RNA_helicase
2546125 Two related superfamilies of putative helicases involved in replication, recombination, repair and expression of DNA and RNA genomes. Nucleic Acids Res 1989;17:4713-4730.

VirE

ATPase_2

Zeta_toxin
12571357 Crystal structure of the plasmid maintenance system epsilon/zeta: functional mechanism of toxin zeta and inactivation by epsilon 2 zeta 2 complex formation. Proc Natl Acad Sci U S A 2003;100:1661-1666.

PDR_CDR
12709320 Functional Similarities and Differences between Candida albicans Cdr1p and Cdr2p Transporters. Antimicrob Agents Chemother 2003;47:1543-1554.

FeoB_N
8407793 Characterization of the ferrous iron uptake system of Escherichia coli. J Bacteriol 1993;175:6212-6219.

RuvB_N
12423347 The RuvABC resolvasome. Eur J Biochem 2002;269:5492-5501.

AAA_7

Roc

NACHT
10782090 The NACHT family - a new group of predicted NTPases implicated in apoptosis and MHC transcription activation. Trends Biochem Sci 2000;25:223-224.

AAA_33

Ploopntkinase3

AAA_30

AAA_29

AAA_28

AAA_5
7646486 A 200-amino acid ATPase module in search of a basic function. Bioessays 1995;17:639-650.
9927482 AAA+: A class of chaperone-like ATPases associated with the assembly, operation, and disassembly of protein complexes. Genome Res 1999;9:27-43.

AAA_25

AAA_24

AAA_23

AAA_22

AAA_21

AAA_19

AAA_18

AAA_17

AAA_16

AAA_15

TIP49
12464178 Reptin and pontin antagonistically regulate heart growth in zebrafish embryos. Cell 2002;111:661-672.
10902922 Chromosome mapping and expression of human tip49 family genes. DNA Seq 2000;11:145-148.

AAA_11

T2SSE

Dynamin_N
8939066 Dynamin GTPase, a force-generating molecular switch. Bioessays 1996;18:885-893.
2144893 Molecular cloning of the microtubule-associated mechanochemical enzyme dynamin reveals homology with a new family of GTP-binding proteins. Nature 1990;347:256-261.

Mg_chelatase
9359397 Mechanism and regulation of Mg-chelatase. Biochem J 1997;327:321-333.
9457877 Reconstitution of an active magnesium chelatase enzyme complex from the bchI, -D, and -H gene products of the green sulfur bacterium Chlorobium vibrioforme expressed in Escherichia coli. J Bacteriol 1998;180:699-704.

cobW
9140970 The HypB protein from Bradyrhizobium japonicum can store nickel and is required for the nickel-dependent transcriptional regulation of hydrogenase. Mol Microbiol 1997;24:119-128.
9209019 Characterization of UreG, identification of a UreD-UreF-UreG complex, and evidence suggesting that a nucleotide-binding site in UreG is required for in vivo metallocenter assembly of Klebsiella aerogenes urease. J Bacteriol 1997;179:4081-4086.
8423137 The product of the hypB gene, which is required for nickel incorporation into hydrogenases, is a novel guanine nucleotide-binding protein. J Bacteriol 1993;175:630-635.
1624427 Klebsiella aerogenes urease gene cluster: sequence of ureD and demonstration that four accessory genes (ureD, ureE, ureF, and ureG) are involved in nickel metallocenter biosynthesis. J Bacteriol 1992;174:4324-4330.
1655697 Nucleotide sequence and genetic analysis of a 13.1-kilobase-pair Pseudomonas denitrificans DNA fragment containing five cob genes and identification of structural genes encoding Cob(I)alamin adenosyltransferase, cobyric acid synthase, and bifunctional cob J Bacteriol 1991;173:6074-6087.

ABC_ATPase

Rad17
10208430 hRAD17, a structural homolog of the Schizosaccharomyces pombe RAD17 cell cycle checkpoint gene, stimulates p53 accumulation. Oncogene 1999;18:1689-1699.

NTPase_1

RsgA_GTPase

SMC_N
10429180 Structural maintenance of chromosomes (SMC) proteins: conserved molecular properties for multiple biological functions. Eur J Biochem 1999;263:6-13.
9640531 SMC protein complexes and higher-order chromosome dynamics. Curr Opin Cell Biol 1998;10:317-322.

AAA_14

Domain	Description	Evalue	Bits	GA	Start	End
ABC_trans_N	ABC-transporter N-terminal	6E-13	41	25.40	60	151
RsgA_GTPase	RsgA GTPase	0.00011	14	30.00	173	219
ABC_ATPase	Predicted ATPase of the ABC class	0.0045	7	19.30	175	207
ABC_tran	ABC transporter	2E-20	65	23.10	176	359
TsaE	Threonylcarbamoyl adenosine biosynthesis protein TsaE	0.082	5	26.60	176	211
T2SSE	Type II/IV secretion system protein	0.0015	9	24.90	177	213
AAA_25	AAA domain	1.4E-05	16	27.00	179	207
AAA_11	AAA domain	0.00062	11	27.00	180	212
AAA_7	P-loop containing dynein motor region	0.0033	9	25.80	182	221
AAA_30	AAA domain	0.0012	10	27.00	185	210
Rad17	Rad17 cell cycle checkpoint protein	0.00067	11	19.70	185	222
AAA_29	P-loop containing region of AAA domain	8.6E-06	17	27.00	185	206
ATPase_2	ATPase domain predominantly from Archaea	0.0027	9	33.20	185	235
TIP49	TIP49 C-terminus	0.00046	11	23.80	185	242
AAA_19	AAA domain	0.0073	8	25.10	185	214
AAA_22	AAA domain	0.00012	14	27.00	186	215
AAA_16	AAA ATPase domain	2.2E-05	17	32.60	186	213
AAA_15	AAA ATPase domain	0.012	7	32.10	186	244
NACHT	NACHT domain	0.0012	11	20.40	187	213
Ploopntkinase3	P-loop Nucleotide Kinase3	0.00018	13	27.00	187	216
SMC_N	RecF/RecN/SMC N terminal domain	0.00047	11	40.00	187	377
VirE	Virulence-associated protein E	0.25	2	21.50	187	209
AAA_14	AAA domain	0.0053	9	27.00	187	232
AAA_24	AAA domain	0.011	7	27.00	188	206
SRP54	SRP54-type protein, GTPase domain	0.062	5	20.50	188	217
AAA_23	AAA domain	0.00032	13	27.00	188	241
AAA_21	AAA domain, putative AbiEii toxin, Type IV TA system	0.0021	10	27.00	188	208
Zeta_toxin	Zeta toxin	0.0019	9	20.10	188	254
cobW	CobW/HypB/UreG, nucleotide-binding domain	0.0028	9	20.70	188	209
RuvB_N	Holliday junction DNA helicase ruvB N-terminus	0.0016	10	20.00	189	218
AAA_33	AAA domain	0.00063	12	27.00	189	211
DUF2075	Uncharacterized conserved protein (DUF2075)	0.0009	10	20.30	189	229
Mg_chelatase	Magnesium chelatase, subunit ChlI	0.012	7	20.30	189	209
PduV-EutP	Ethanolamine utilisation - propanediol utilisation	0.075	5	20.50	189	222
Septin	Septin	0.068	4	20.00	190	258
FeoB_N	Ferrous iron transport protein B	0.11	4	21.20	190	210
AAA	ATPase family associated with various cellular activities (AAA)	6.7E-05	15	20.80	190	247
AAA_18	AAA domain	0.00014	14	29.40	190	235
Roc	Ras of Complex, Roc, domain of DAPkinase	0.038	6	27.00	190	228
RNA_helicase	RNA helicase	0.00069	12	21.50	190	231
MMR_HSR1	GTPase of unknown function	0.00053	12	24.50	190	233
AAA_5	AAA domain (dynein-related subfamily)	0.00039	12	20.80	190	213
AAA_28	AAA domain	0.0045	9	27.00	191	208
NTPase_1	NTPase	0.0018	10	23.90	191	223
Dynamin_N	Dynamin family	0.65	2	21.00	192	209
AAA_17	AAA domain	0.0015	11	27.00	192	220
Mg_chelatase	Magnesium chelatase, subunit ChlI	0.84	1	20.30	333	360
ABC2_membrane_7	ABC-2 type transporter	1.7E-08	25	22.70	392	443
ABC2_membrane	ABC-2 type transporter	0	145	25.50	513	725
PDR_assoc	Plant PDR ABC transporter associated	7.9E-27	85	22.70	730	793
PDR_CDR	CDR ABC transporter	0.54	2	20.50	758	785
VirE	Virulence-associated protein E	0.0083	7	21.50	850	888
AAA_16	AAA ATPase domain	0.00058	12	32.60	852	906
ABC_tran	ABC transporter	3E-24	78	23.10	854	1006
ABC_ATPase	Predicted ATPase of the ABC class	0.13	3	19.30	855	884
AAA_25	AAA domain	0.00018	13	27.00	856	885
TsaE	Threonylcarbamoyl adenosine biosynthesis protein TsaE	0.014	7	26.60	860	885
AAA_15	AAA ATPase domain	0.038	5	32.10	861	884
AAA_23	AAA domain	0.00015	14	27.00	861	886
AAA_30	AAA domain	0.0024	9	27.00	862	885
RsgA_GTPase	RsgA GTPase	0.0001	14	30.00	865	888
AAA_29	P-loop containing region of AAA domain	7.6E-05	14	27.00	866	884
SMC_N	RecF/RecN/SMC N terminal domain	0.0021	9	40.00	866	1040
AAA_21	AAA domain, putative AbiEii toxin, Type IV TA system	5.8E-05	15	27.00	866	931
Zeta_toxin	Zeta toxin	0.003	9	20.10	866	935
NACHT	NACHT domain	0.026	6	20.40	867	885
cobW	CobW/HypB/UreG, nucleotide-binding domain	0.0087	7	20.70	867	885
AAA_22	AAA domain	0.012	8	27.00	867	886
AAA_33	AAA domain	0.0018	10	27.00	867	889
FeoB_N	Ferrous iron transport protein B	0.051	5	21.20	867	888
SRP54	SRP54-type protein, GTPase domain	0.1	4	20.50	867	885
Dynamin_N	Dynamin family	0.013	7	21.00	868	991
AAA_24	AAA domain	0.071	5	27.00	868	882
AAA_14	AAA domain	0.95	1	27.00	868	887
Roc	Ras of Complex, Roc, domain of DAPkinase	0.016	7	27.00	868	903
AAA_7	P-loop containing dynein motor region	0.042	5	25.80	868	918
MMR_HSR1	GTPase of unknown function	0.0048	9	24.50	868	888
AAA_28	AAA domain	0.0084	8	27.00	868	889
Ploopntkinase3	P-loop Nucleotide Kinase3	0.063	5	27.00	868	885
AAA_5	AAA domain (dynein-related subfamily)	0.24	3	20.80	869	886
Rad17	Rad17 cell cycle checkpoint protein	0.35	2	19.70	869	894
RNA_helicase	RNA helicase	0.027	7	21.50	869	908
NTPase_1	NTPase	0.86	1	23.90	869	883
RuvB_N	Holliday junction DNA helicase ruvB N-terminus	0.44	2	20.00	869	886
AAA	ATPase family associated with various cellular activities (AAA)	0.02	7	20.80	869	1004
AAA_18	AAA domain	0.0093	8	29.40	869	943
PduV-EutP	Ethanolamine utilisation - propanediol utilisation	0.026	6	20.50	869	887
Septin	Septin	0.045	5	20.00	869	888
AAA_17	AAA domain	1	2	27.00	870	885
AAA_21	AAA domain, putative AbiEii toxin, Type IV TA system	0.00011	14	27.00	994	1039
NTPase_1	NTPase	0.51	2	23.90	1014	1042
ABC2_membrane_7	ABC-2 type transporter	8.4E-07	20	22.70	1035	1078
ABC2_membrane	ABC-2 type transporter	0	178	25.50	1152	1363
ABC2_membrane_7	ABC-2 type transporter	0.055	4	22.70	1228	1311
PDR_CDR	CDR ABC transporter	0.0032	9	20.50	1382	1423
PDR_assoc	Plant PDR ABC transporter associated	0.0017	10	22.70	1398	1422